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Browsing by Author "Gustafsson, Andreas"

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    Anpassning av .NET-funktionalitet för Microsoft Excel
    (2010-03-04T15:22:27Z) Gustafsson, Andreas; Göteborgs universitet/Institutionen för data- och informationsteknik; University of Gothenburg/Department of Computer Science and Engineering
    The .NET Framework is a widely used system component for Microsoft Windows. This thesis describes how the functionality of the framework can be adapted to Microsoft Excel. Specific operations, such as integration of user interfaces, database connections and the ability to divide programs into smaller components, are discussed. A number of architectural - and design patterns to facilitate development are analysed. Several techniques have been made up in consultation with experienced programmers. These techniques were further developed by implementing a number of test programs. The results of the study are a number of standard classes for future usage and a larger pilot project containing most of the analysed functionality.
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    Hur hittar man och undervisar elever som är särbegåvade? - En intervjustudie om matematiklärares tankar kring särbegåvade elever
    (2019) Gustafsson, Andreas; Institutionen för matematiska vetenskaper
    The purpose of this final degree project is to investigate how gifted students, in math class, differ from other students and how gifted students can be identified in a school environment. The study further investigates what, if any, accommodations math teachers make to help gifted students develop their full potential. Accommodations are investigated both on an individual level and on a group level. Giftedness in this study is not limited to students who are particularly talented in math. The study instead tries to view gifted students in a broader way regardless of their interest or success in mathematics. As context an overview of previous research on the topics of intelligence, giftedness and accommodations for gifted students are given. To answer the research questions five math teachers, with knowledge of gifted students, are interviewed.
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    De leker ju självmant och leken är fantastisk!
    (2015) Gustafsson, Andreas; Göteborgs Universitet/Institutionen för pedagogik, kommunikation och lärande
    Anledningen till att vi valde att bedriva vår studie var för att vi ansåg att det finns mycket forskning om den fysiska aktiviteten men inte i relation till fritidshemmet. Vårt syfte var att beskriva fritidspedagogers uppfattningar om den fysiska aktiviteten på fritidshemmet. Våra frågeställningar delades upp i tre olika teman och utgick ifrån olika teorier. Första temat handlar om fritidspedagogers attityder till den fysiska aktiviteten och utgick ifrån habitusbegreppet. Andra frågan fokuserar på hur fritidspedagoger upplever sin roll i arbetet med fysisk aktivitet och utgick ifrån ett rollteoretiskt perspektiv. Sista temat inriktades på fritidspedagogernas beskrivning av det didaktiska tillvägagångssättet och grundades i didaktikens vad och varför. Som metod använde vi oss utav en kvalitativ forskningsansats med semistrukturerade intervjuer. För att analysera intervjuerna så utgick vi från en kvalitativ innehållsanalys för att få fram resultatet som vi sedan förde diskussion om relaterat till tidigare forskning och teori. Studiens resultat visade att användningen av den fysiska aktiviteten påverkas av fritidspedagogernas tidigare upplevelser. Fritidspedagogerna upplever sin roll som viktig i arbetet med fysisk aktivitet och påverkas av barns och föräldrars förväntningar men känner otydliga förväntningar från varandra inom arbetslaget. De använder även den fysiska aktiviteten i form av lek och utomhuspedagogik i det didaktiska tillvägagångssättet för att det medför positiva aspekter för barnen.
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    Proteomic analysis of human bile reveals potential biomarkers for cholangiocarcinoma
    (2016-02-11) Gustafsson, Andreas; University of Gothenburg / Institute of Medicine; Göteborgs universitet / Institutionen för medicin
    Degree Project Thesis, Programme in Medicine. TITLE: Proteomic analysis of human bile reveals potential biomarkers for cholangiocarcinoma. Background: Cholangiocarcinoma (CC), is the second most common primary liver cancer in most parts of the world. In western countries, primary sclerosing cholangitis (PSC) is one of the most common causes of CC. CC has a low survival rate, between 2-30% depending on type and spread, and diagnosis often comes late in the development of the tumor, due to a late clinical presentation and unsatisfactory diagnostic methods. It is particularly difficult to determine if biliary strictures in patients with PSC are benign or malignant in nature. In recent years, there has been an increased interest in the use of proteomic analysis of bile for the discovery of potential biomarkers to aid in the diagnosis of CC. Objective: The aim was to determine the existence of proteins whose relative abundance in bile differs depending on the underlying disease, in patients with biliary strictures. The main ambition was to discover one or more proteins with the ability to distinguish a benign biliary stricture from a malignant stricture in patients with PSC. Methods: Bile samples from 37 patients were analyzed in this prospective exploratory study, including 5 patients with de novo CC, 4 with CC and PSC, 7 with PSC only, 6 with pancreatic cancer, and 15 controls. The bile was aspirated from patients undergoing endoscopic retrograde cholangiopancreatography. For one sample, bile was aspirated by percutaneous transhepatic cholangiography. Nano liquid chromatography tandem mass spectrometry was used for mass analysis. Proteins were identified by searches against a public database of human peptide sequences. Lastly, SPSS Statistical Package was used to calculate if there was a statistically significant difference in abundance of proteins between patient groups. Results: A total of 6 proteins were identified where the relative abundance differed significantly between patient groups (p < 0.05). The most promising finding was that the known tumor suppressor Receptor-type tyrosine-protein phosphatase eta (R-PTP-eta) was less abundant in patients with CC than in the control population and patients with PSC only. Conclusions: The differential abundance of certain proteins present in human bile, such as RPTP- eta, can be used to differentiate CC from other diseases of the bile ducts. None of the proteins described in this study were alone able to distinguish a benign biliary stricture from a malignant stricture in patients with PSC. Further studies are warranted to examine the usefulness of these proteins as clinical tumor markers for CC

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