Browsing by Author "Johansson, Bengt W"

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    Kyla, hälsa och läkemedel
    (Arbetslivsinstitutet, 2002) Lundgren, Hans; Gyllerup, Staffan; Holmér, Ingvar; Johansson, Bengt W
    With the purpose of compiling knowledge and experiences about function and use of drugs and medication under cold conditions the National Institute for Working Life (Arbetslivsinstitutet) in collaboration with Societas pro Scientia Frigoris, an independent and non-profit organisation for promotion of knowledge of man and cold, arranged an interdisciplinary symposium on the theme Drugs and Cold . The symposium was held during two days in Februari 2000 at the castle of Snogeholm in the southern part of Sweden. Ten leading scientists with different background were invited to talk about their specific subject. One of the possible explanations to the increased mortality during the winter season could be the increased activity of the sympathetic nervous system leading to a rise in heart rate and in blood pressure. Inhalation of great amounts of cold and dry air, could not only worsen the symptoms of bronchial asthma, but probably even initiate a hypersensitive reaction in the respiratory tract. Some studies of cross country skiers point in that direction. For the asthmatics and their doctors the findings that freone based inhalators may not function properly in cold air, should be of the greatest interest. Studies of the hedgehog s heart, a hibernator, yield new knowledge of mechanisms giving rise to arrhythmia during hypothermia. Of great interest is the study of prescribing patterns by doctors in different climate areas of our country. Furthermore, the knowledge of the effects of drugs and their kinetics during hypothermia is little considered in clinical practise. Drug effects and dependence of body temperature was discussed. This dependence is not well known, but important, because hypothermia becomes more and more accepted as a therapeutic aid in the treatment of several diseases. But cold can also be a friend. Two lectures dealt with this aspect. One concerned the beneficial effects of cold during surgery and another cold treatment of acute tissue injuries. We hope that the Proceedings of this symposium will advance the knowledge of interaction effects of cold and drugs among clinicians, health care personnel as well as outdoor people and at the same time being a well of inspiration for future research. The symposium was supported by grants from the National Institute for Working Life, National Social Board, Astra Zeneca AB, Novartis, Knoll, and Item Development.