Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet: Recent submissions
Visas titlar 481-500 av 10942
-
The physiological processing of Alzheimer-associated amyloid beta precursor protein in human and animal-derived neuronal models
(2020-02-27)Alzheimer’s disease (AD) is characterized by cognitive impairment due to the loss of structure and/or function of neurons, and amyloid plaques composed of aggregated-amyloid beta (Aβ) peptides, primarily species ending at ... -
Ghrelin in feeding: new insights into its role and the neurocircuits involved
(2020-02-27)Appetite, originally evolved to ensure we consume enough of diverse nutrients to survive famines, has lost its survival advantage in our modern society, where food is plentiful. The hedonic aspect of appetite can indeed ... -
Cardiovascular outcomes and extra-articular manifestations in patients with spondyloarthritis
(2020-02-27)Background: Spondyloarthritis (SpA) is a cluster of rheumatic diseases with similar clinical features, including association with extra-articular manifestations such as anterior uveitis (AU), inflammatory bowel disease ... -
Standardiseringsarbetets kollektiva praktik. En studie om att kvalitetssäkra integrationssatsningen Samhällsorientering för nyanlända.
(2020-02-27)Societal efforts to support the integration of newly arrived immigrants have been repeatedly highlighted in the political debate in Sweden and they are described as inadequate and ineffective. Demands have been made for ... -
Management regimes for lawns and hedges in historic gardens
(2020-02-26)Management regimes for lawns and hedges in historic gardens This research investigates and compares eighteenth-century and contemporary garden management methods with a focus on the structural elements of lawns and hedges ... -
Att urskilja grafiska aspekter av derivata – hur elevernas möjligheter påverkas av innehållets behandling i undervisningen
(2020-02-19)The aim of this thesis is to investigate in what ways students’ opportunities to discern graphical aspects of the concept of derivative can be related to the design of instruction. The thesis is based on two empirical ... -
Periprosthetic femoral fracture after total hip replacement. Incidence, risk factors, and treatment
(2020-02-18)This thesis investigates the incidence of surgically treated periprosthetic femoral fractures (PPFF) in Sweden between 2001 and 2011, the demography of this population, risk factors that may contribute to its occurrence ... -
Bipolar disorders: Subtypes, treatments, and health inequalities
(2020-02-18)This thesis comprises five studies based on prospective, longitudinal data from the Swedish national quality register BipoläR. Study I examined the differences between bipolar subtype I and II with respect to clinical ... -
Tumor cell heterogeneity profiling using single-cell analysis
(2020-02-13)Cancer is a diverse disease with large variations between tumor types and patients regarding tumor progression and prognosis. Additionally, most individual tumors are heterogeneous, containing subpopulations of cells with ... -
Sex steroids, IGF-I, and vascular morphology from birth to adulthood in individuals born small for gestational age
(2020-02-11)Abstract Aim: To study whether there is an association between size at birth, sex steroids, IGF-I, and retinal vascular morphology. Patients and methods: Two different cohorts were studied. In paper I, 25 young adult men ... -
Protein Structural Dynamics Revealed by Time-Resolved X-ray Solution Scattering
(2020-02-11)Proteins fold in very specific three-dimensional structures within a few seconds. Highly complex and organized, their three-dimensional structure is closely related and often essential for their function. They perform a ... -
Understanding and Supporting Software Design in Model-Based Software Engineering
(2020-02-10)Model-Based Software Engineering (MBSE) is a software development approach in which models can serve a multitude of purposes. On the one hand, models can be used for ideation, to stimulate creative thinking, and facilitate ... -
The professional preschool teacher under conditions of change – Competence and intentions in pedagogical practices.
(2020-02-07)This thesis explores the relationship between preschool teachers’ professional competence and their pedagogical practices. Specifically, preschool teachers’ considerations on two pedagogical practices are studied: (i) ... -
Teachers meeting the challenges of the Swedish school system. Agents within boundaries
(2020-02-06)There are many factors that may contribute to explaining variation in teacher quality, which is the key to the schools’ success. These factors include not only teacher characteristics, but also conditions of the teachers’ ... -
Settler-Colonial Assemblages and the Making of the Israeli Frontier: Palestinian experiences of (in)security, surveillance and carceral geographies
(2020-02-06)This dissertation examines the operations of contemporary Israeli security machinery as it unfolds in the course of expanding the Israeli colonial frontier over Palestinian rural areas of the occupied West Bank. Since the ... -
Outcome of Graves disease
(2020-02-05)Graves' disease (GD) is an autoimmune condition with elevated thyroid hormone levels and symptoms suggesting an affected brain. These symptoms often resolve with treatment but, for some patients, GD results in a long period ... -
Translational studies of metastatic melanoma in the era of immunotherapy - from humanized mouse models to clinical trials
(2020-01-30)Immunotherapy with PD-1 inhibitors has transformed the treatment of met-astatic cutaneous mela- noma, and can lead to complete and durable responses in a proportion of patients. However, in around half of the patients, the ... -
Health-economic evaluations of person-centred care
(2020-01-28)Person-centred care aims at making the individual partake in the healthcare decisionmaking and at supporting individual health management. This stands in contrast to usual care, which typically has more focus on the ... -
Febrile Seizures and associated neurodevelopmental disorder
(2020-01-22)Background: Febrile seizures (FS) are common in young children. There is a lack of knowledge about possible associations between FS and the child’s cognitive and behavioural development. Aim: Gain further insight into the ... -
The balancing act of living with symptoms. Patient-reported data and quality of care during and after treatment with proton beam therapy in patients with brain tumors
(2020-01-21)is thesis focuses on patients with primary brain tumors undergoing proton beam therapy (PBT) and the consequences of the treatment. Quality of care (QoC) in a recently established clinic in Sweden was also evaluated. ...