Institute of Medicine / Institutionen för medicin: Recent submissions
Now showing items 261-280 of 1073
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Potential biomarkers for acute and chronic rejection after lung transplantation
(2016-10-26)Abstract Chronic rejection in the form of bronchiolitis obliterans syndrome (BOS) is the main hindrance for long-term survival after lung transplantation. Repeated acute rejections (AR) constitute a major risk factor for ... -
Antimicrobial peptides in the treatment of infectious and inflammatory conditions - Preclinical studies of mechanism of action, efficacy, and safety
(2016-10-20)The rapid emergence of antibiotic-resistant microbes worldwide and the urgent need of new antimicrobial agents have stimulated interest in antimicrobial peptides (AMPs) as new therapeutics for treatment of infectious ... -
Work ability in young adults
(2016-09-29)Young adults may need special attention in their shift from student life to working life, to guarantee work ability. Being new at the workplace, they may encounter high expectations, resulting in high job demands. Also, ... -
Infectious immunity and pneumococcal vaccine responses in multiple myeloma and related disorders
(2016-09-15)Multiple myeloma (MM), Waldenstrom’s macroglobulinemia (WM), and monoclonal gammopathy of undetermined significance (MGUS) are B cell conditions associated with suppressed immune functions and susceptibility to infection. ... -
Platelet Inhibition and Bleeding Complications in Cardiac Surgery Patients - Clinical and experimental studies
(2016-09-02)BACKGROUND AND OBJECTIVE Dual antiplatelet therapy (DAPT) with acetylsalicylic acid and a P2Y12 inhibitor (clopidogrel, ticagrelor, or prasugrel) reduces thrombotic events in patients with acute coronary syndrome (ACS), ... -
Anti-vibration Gloves - in Theory and Practice
(Arbets- och miljömedicin, Göteborgs universitet, 2016-06-06)Vibrations from hand-held machinery are a major problem in the Swedish labour force. In 2009, 14% of men and 3% of women of employed in Sweden reported exposure to hand-arm vibration at least a quarter of their working ... -
Aspects of Plasminiogen Activator Inhibitor 1 in Metabolic Syndrome
(2016-05-31)Plasminogen activator inhibitor 1 (PAI-1) is the main inhibitor of the fibrinolytic system and binds irreversibly to tissue-type plasminogen activator (t-PA), and thereby inhibits the protective action of t-PA against ... -
149. Diesel Engine Exhaust
(Arbets- och miljömedicin vid Göteborgs universitet & Arbetsmiljöverket, 2016-06-08)Diesel engine exhaust is a complex mixture of gaseous and particulate compounds produced during the combustion of diesel fuels. The gas phase includes carbon dioxide, nitrogen oxides (NOX), carbon monoxide and small amounts ... -
Physical activity and well-being among adolescents: A public health perspective
(2016-05-26)Background: Physical activity among adolescents is diminishing and worldwide about 80% of 13–15-year-old adolescents do not meet the public health guidelines of minimum 60 minutes of daily physical activity of at least ... -
Insulin resistance and cardiovascular function - Observational, translational and interventional studies
(2016-05-26)Background: Microvascular disease is now recognized as an important driver for cardiovascular mortality and morbidity. Diabetic patients are known to suffer from this condition, leading to e.g. coronary ischemia as well ... -
Protein kinase STK25 is a regulator of hepatic lipid partitioning and whole body metabolism
(2016-05-24)In past decade, type 2 diabetes (T2D) and associated metabolic complications have become a major global threat for human health with epidemic increase in incidence. Currently available treatments for T2D have several ... -
Microbial regulation of Insulin-like peptide 5 and its implication on metabolism and bariatric surgery
(2016-05-23)The microbial community in our gastrointestinal tract, the gut microbiota, has great impact on our physiology. Particularly, the role for gut microbiota in host health and disease has been associated with modulation of gut ... -
Extracellular Vesicles and RNA interference in tumors
(2016-05-18)Extracellular vesicles (EVs) including apoptotic bodies (ABs), microvesicles (MVs), exosomes (EXOs) and cell derived artificial nanovesicles (NVs) are important mediators of cell-to-cell communication, in part by transferring ... -
Epigenetic regulation of gene expression in the vascular endothelium
(2016-05-12)Epigenetic mechanisms, such as DNA methylation and histone modifications, constitute one way for a cell or an organism to respond to changes in the surrounding environment. While histone modifications are recognized to ... -
Graft-versus-Host Disease: Eosinophils, Chimerism and Clinical Features in Patients Undergoing Allogeneic Hematopoietic Stem Cell or Multivisceral Transplantation
(2016-05-12)Abstract Graft-versus-host disease (GVHD) is a potentially severe complication that may develop after allogeneic hematopoietic stem cell transplantation (HSCT). It can also occur after transplantation with isolated ... -
Traumatic episodes related to the genocide period, mental health effects and perceived barriers to care facing young adults in Rwanda
(2016-05-09)Aims: To investigate mental health status in a Rwandan population aged 20-35 years, their associations with traumatic episodes experienced during the 1994 genocide and life time, and barriers to care as perceived by health ... -
Pharmacological stimulation of endothelial function and long-term impact of hypertension in man
(2016-05-06)Background: Ischemic heart disease is a major cause of death globally. Rupture of a coronary atherosclerotic plaque with occluding thrombus formation is the main cause of myocardial ischemia and infarction. A healthy ... -
Epidemiological Aspects of Renal Impairment in Patients with Type 2 Diabetes
(2016-05-04)Diabetes is a leading cause of renal impairment (RI) and indication of the need for renal replacement therapy in many parts of the world. Albuminuria and RI are the two main forms of diabetic kidney disease. The overall ... -
Bleeding tendency and health-related quality of life in carriers of haemophilia
(2016-05-02)Haemophilia A and B are X-linked disorders caused by impaired synthesis of coagulation factors VIII and IX, respectively. Women who carry the haemophilia trait have about 50 % of normal factor levels. Due to skewed ... -
The association between eczema, asthma and rhinitis -population studies of prevalence and risk factors among adults
(2016-04-28)Background: Allergic diseases such as asthma, rhinitis and eczema have increased significantly since the middle of the past century and are now common conditions among both children and adults. The increase was observed ...