Doctoral Theses / Doktorsavhandlingar Institutionen för kemi och molekylärbiologi: Recent submissions
Now showing items 1-20 of 163
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Escape from the cage: Ultrafast structural dynamics of photodissociation reactions observed with X-ray solution scattering
The environment of a molecule is known to greatly impact the course of a reaction. Such an environment can, for instance, be the solvent in a solution phase reaction or the amino acid residues surrounding a chromophore in ... -
Light and X-ray scattering investigations of microtubules subjected to oscillating electric fields
(2022-12-08)I vårt dagliga liv blir vi utsatta för oscillerande elektriska fält av olika frekvenser. Dessa fält inkluderar mobiltelefoner, wifi, bluetooth, radar för navigering, radar från bilar, kommunikationssatelliter, samt GPS. ... -
Strong exciton-photon and exciton-exciton coupling and its effects on molecular photophysics
(2022-12-05)The energy of molecular states and their transition dynamics form the key properties to understand the photophysics of organic molecules. Strong exciton-photon and exciton-exciton couplings enable the possibility to ... -
Functional details of human HtrA2 protease studied by NMR spectroscopy
(2022-11-24)Cells rely on an array of cellular machineries in the protein quality control system (PQC) to maintain the health of the collective proteome. The HtrA family of serine proteases are found in all kingdoms of life and function ... -
Formation and Transformation of Atmospheric Brown Carbon (BrC)
(2022-11-23)Atmospheric brown carbon (BrC) aerosol absorbs light in the UV-Vis spectrum and has poorly constrained but potentially large climate forcing impacts. Most current climate models lack detailed chemistry and interlinked ... -
Functional roles of protein phase separated assemblies in cellular stress response and proteinopathies
(2022-11-09)For a long time, pertinent biological conundrums, such as the organization and compartmentalization of the cytoplasm and nucleoplasm, perplexed the scientific community. The organization of the complex biochemistry in an ... -
Microtubule structure and function as perturbed by electromagnetic fields
(2022-11-08)Frontlinjen för strukturbiologisk forskning ligger idag i att avbilda proteiner i rörelse. För att förstå hur proteiner fungerar rent strukturellt krävs avbildningsmetoder med en tid- och rums-upplösning anpassad för den ... -
Photocatalysis beyond conventional precious metal complexes
(2022-11-08)Precious metals, e.g. Ru and Ir, are expensive, scarce and non-renewable resources. As oppose to many renewable resources, these cannot be deliberately produced wherever one wishes. The mining of these metal ores is ... -
Proteostasis during arsenite stress in Saccharomyces cerevisiae
(2022-11-02)Around 200 million people are exposed to high levels of arsenic through contaminated soil and, consequently, contaminated food and drinking water. Arsenic exposure is associated with several malignancies, from different ... -
Antibiotic sensitivity and horizontal gene transfer in Escherichia coli - A genome-wide perspective
(2022-11-01)Since their discovery in the early 20th century, antibiotics have truly revolutionized human medicine. They have allowed us to treat diseases that were previously untreatable and have become a staple of modern medicine. ... -
Structural and dynamical basis of NusA´s role in transcription-coupled DNA repair
(2022-10-28)DNA repair processes involves a host of repair machineries that are able to recognize and repair the damaged DNA. Nucleotide excision repair (NER) pathway is one of these processes exploited by cells to remove bulky DNA ... -
Structural characterization of electron transfer in D.m (6-4) photolyase by time-resolved X-ray crystallography
(2022-10-18)Photolyases are flavoproteins widely spread in bacteria, archea, fungi, plants and animals. These enzymes absorb blue light and use it as an energy source for repairing damages that are induced on DNA after a prolonged ... -
The Genetics of Adaptation and Evolvability in Yeast
(2022-10-18)Evolution is the hereditary change in life forms that has shaped the divergence of all organisms that inhabit planet Earth. I used the yeast Saccharomyces cerevisiae to study how adaptive evolution increases the fitness ... -
Unravelling Mechanistic Insights of Eukaryotic Transcriptional Control
(2022-10-13)DNA transcription involves the association of multiple proteins with DNA to convert the genetic information into messenger-RNA transcripts, which later will be translated into proteins. Con-trolled regulation of transcription ... -
Alkali Release and Effects on Biomass Thermal Conversion Processes
(2022-09-19)High alkali content is an important feature of biomass, and it has a series of implications for thermal conversion processes. This thesis focuses on the release of alkali during various biomass thermal conversion processes, ... -
Arsenic-induced protein aggregation and toxicity in Saccharomyces cerevisiae
(2022-08-29)Arsenic is prevalent in the environment and this toxic metalloid poses a substantial threat to human health with 100-200 million people worldwide estimated to be at risk. Chronic exposure to arsenic is associated with ... -
On the interactions of ions and odor molecules with nanomaterials in water and synthetic urine
(2022-08-25)Towards the quest of finding materials to be used as adsorbents in real systems, it is crucial to understand the underlying adsorption processesfully. In many applications, adsorption occurs in biological fluids containing ... -
Time-resolved X-ray diffraction and solution scattering studies of Sensory Rhodopsin II in isolation and in complex with its transducer
(2022-05-30)Light is an important source of energy for many living organisms. Many life forms have therefore evolved cellular receptors that are able to sense light and thereby optimise conditions for photosynthesis and pho- totrophy. ... -
Structural Dynamics of Rhodopsins using Time-Resolved X-ray Solution Scattering
(2022-05-11)Light is one of the most important sources of energy and environmental signals, and many organisms adapt in response to the presence of light. This is made possible through specialised proteins called photoreceptors. ... -
Experimental Protein Dynamics and its Role in Predicting Protein Function
(2022-05-04)By studying proteins we learn about the processes that control life, such as important procedures in the body, diseases and eventually find more targeted cures for many diseases. Proteins are constantly being built up ...