Doctoral Theses / Doktorsavhandlingar Institutionen för kemi och molekylärbiologi: Recent submissions
Now showing items 121-140 of 163
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Integrative analysis of osmoregulation in yeast Saccharomyces cerevisiae
(2014-05-06)Similar to other unicellular organisms, yeasts frequently encounter environmental stress such as heat shock, osmotic stress, and nutrition limitations, which challenge their growth potential. To survive, all living cells ... -
Transport by Benthic Macrofauna: Functional Classification and Biogeochemical Response
(2014-04-30)Burrowing and reworking activities by benthic macrofauna regulate rates and pathways during organic matter mineralisation in bioturbated sediments. In so doing, they also affect the overall cycling of elements crucial in ... -
Biogenic Halocarbons in Polar Sea Ice
(2014-04-28)Sea ice is to date a rather poorly investigated part of the cycling of volatile halogenated organic compounds, halocarbons. These compounds are natural sources of reactive iodine and bromine to the atmosphere, and are ... -
Determine the developmental dynamics of primordial follicles in the mouse ovary
(2014-04-15)Ovarian follicles are the basic functional units of the mammalian ovary. Progressive activation of primordial follicles serves as the source of fertilizable ova. In this thesis, by generating the Foxl2-CreERT2 and ... -
Quantum Force in Wigner Space
(2014-04-08)In this thesis, I will present effective methods to study quantum dynamics using trajec- tories. Our methods are based on a method named the Classical Wigner model which starts with a quantum initial condition and generates ... -
Exploring nanosystems for biomedical applications focusing on photodynamic therapy and drug delivery
(2014-03-18)The increasing incidences of cancer and related deaths call for the development of new and improved treatment modalities. Photodynamic therapy (PDT) today is an alternative to conventional treatments, but has limitations. ... -
Links between Aging and Proteostasis Decline in Saccharomyces cerevisiae
(2014-03-07)Proteins are continuously synthesized and degraded to meet the demands of the cell. Hence, a proper balance between synthesis, folding, disaggregation and degradation is of essence to ensure cell survival. Disruption of ... -
Electrocatalytic properties of Ni hydroxides with Zn or Co in the Ni matrix
(2014-01-17)The majority of the work in this thesis has been made with the improvement of the systems for electrochemical co-generation of chemicals and electricity in mind. This is an appealing but challenging way of producing chemicals ... -
On the exposure assessment of engineered nanoparticles in aquatic environments
(2013-12-10)The socio-economic benefits anticipated with the use and production of nanomaterial and nanoparticles in consumer products are linked to the fulfillment of the requirement for sustainability during the whole material life ... -
New single particle methods for detection and characterization of nanoparticles in environmental samples
(2013-11-28)Nanoparticles (NP) are being used in rapidly increasing quantities which has resulted in concerns about possible harmful effects for health and environment. NP are already undergoing similar risk assessment programs as ... -
Production and Characterisation of Aquaporins and Proton-Translocating Transhydrogenase
(2013-11-15)Dissertation Abstract Water transport in eukaryotic cells is a highly regulated and fine-tuned process. Water channel protein known as aquaporins (AQPs), constitute the main cellular water transport system, preserving ... -
Epoxides as Contact Allergens - Formation, Sensitising Potency and Structure-Activity Relationships
(2013-10-31)Chemicals in our environment with which we have repeated skin contact can cause skin sensitisation (contact allergy). To trigger an immune response a compound (hapten) must be able to penetrate the skin, where it needs to ... -
On Biogenic Halocarbons in Antarctic Waters
(2013-10-17)Little is known regarding the distribution of naturally produced volatile halogenated organic compounds, halocarbons, in Antarctic waters and the contribution of these waters to the global atmospheric load of halogens. In ... -
Development and use of an optical pCO2 sensor in marine studies
(2013-10-04)Partial pressure of CO2 (pCO2) is one of the most important parameters, which are measured in the global ocean in conjunction with ocean acidification studies. It is also a parameter of great interest to aquaculture and ... -
Character and Function of Anammox Bacteria under Environmental Stress
(2013-09-16)During the last few decades observations of novel processes involved in nitrogen transformations have fundamentally challenged the view of pathways and controlling mechanisms during local and global nitrogen cycling. ... -
Allergenic Oxidation Products from Fragrance Terpenes. Chemical Analysis and Determination of Sensitizing Potency
(2013-09-05)The ubiquitous presence of fragrance compounds in consumer products has resulted in a high frequency of contact allergy to fragrances in the population. For prevention purposes and according to EU regulations, cosmetics ... -
Development of novel serotonin 5-HT6 and dopamine D2 receptor ligands and MAO A inhibitors - Synthesis, structure-activity relationships and pharmacological characterization
(2013-09-05)It is known since the 1950s that enhancement of the levels of the monoamines dopamine (DA), serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE) in the brain will relieve the symptoms of major depression, and ... -
Low biocide emission antifouling based on a novel route of barnacle intoxication
(2013-05-17)Marine biofouling can be defined as the colonization of man-made surfaces in seawater by microscopic and macroscopic organisms. This phenomenon can result in great loss of function and effectiveness both for cruising ships ... -
The Mechanisms of Exocytosis Studied in Cells and Models with Amperometry
(2013-05-15)Exocytosis is the universal basis for neuronal communication, allowing the controlled release of neurotransmitter molecules from the presynaptic cell. Exocytosis has been widely studied in many systems. However, the details ... -
Iron catalyzed C-C coupling reactions - mechanistic investigations
(2013-05-14)The mechanism of the iron catalyzed cross coupling of aryl electrophiles with alkyl Grignard reagents was studied. The reaction proceeds via a rate-limiting oxidative addition of the aryl halide to an Fe(I) complex generated ...