Faculty of Science / Naturvetenskapliga fakulteten: Recent submissions
Visas titlar 461-480 av 836
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Purine and Pyrazolopyrimidine Derivatives: Design and Synthesis of Chemical Tools for Biological Applications
(2014-12-04)Purines can be found in a multitude of naturally occurring compounds with a range of functions. This thesis describes the design and synthesis of purines and structurally related pyrazolopyrimidine derivatives intended for ... -
Modulating Sirtuin Activity - Design, Synthesis and Evaluation of Sirtuin 2 Inhibitors
(2014-11-21)Sirtuins (SIRTs) are NAD+-dependent lysine deacetylating enzymes targeting histones and a multitude of non-histone proteins. The SIRTs have been related to important cellular processes such as gene expression, cell ... -
Formalizing Refinements and Constructive Algebra in Type Theory
(2014-11-21)The extensive use of computers in mathematics and engineering has led to an increased demand for reliability in the implementation of algorithms in computer algebra systems. One way to increase the reliability is to formally ... -
Model-Based Engineering for Embedded Systems in Practice
(2014-11-18)Model-Based Engineering (MBE) aims at increasing the e↵ectiveness of engineering by using models as key artifacts in the development process. While empirical studies on the use and the e↵ects of MBE in industry generally ... -
X-ray free-electron laser based methods for structural and ultrafast dynamics studies of a photosynthetic reaction centre
(2014-11-14)Life on earth is fuelled by the energy of sunlight, which must first be captured and converted into a chemical energy form useful to the cell. This process is known as photosynthesis and the major pathway of this energy ... -
Non-Linear Canonical Methods in Strongly Correlated Electron Systems
(2014-11-14)In this thesis some new ideas to perform the analysis of Strongly Correlated Electronic Systems (SCES) are developed. In particular the use of non-linear canonical transformations is considered thoroughly. Using such ... -
Climate Change and the Norway lobster -Effects of Multiple Stressors on Early Development
(2014-11-07)Climate change together with anthropogenic eutrophication have led to, and will lead to, shifts in a number of abiotic factors in the oceans, such as temperature, carbon dioxide [CO2], pH, oxygen saturation and salinity. ... -
Blue Oceans with Blue Mussels - Management and planning of mussel farming in coastal ecosystems
(2014-11-03)Eutrophication is one of the largest and most serious global threats to the marine environment. The effect of eutrophication has become increasingly clear during recent time, and major economic and political efforts are ... -
Genetic variation in natural populations: a modeller's perspective
(2014-10-29)Thanks to advances in genome sequencing, empirical patterns of within- and between-species genetic variation are readily available. By studying these patterns much has been learned about the evolutionary histories of ... -
Plastidial phosphate transport in plants
(2014-10-24)Phosphorus is an essential element for all living organisms and is central to the genetics and energetics of life. Inorganic phosphate (Pi) is recurrently involved in protein regulation and signal transduction but also in ... -
Intrinsically Disordered Domains of the B Cell Receptor Cell-Free Expression and Characterization by NMR
(2014-10-23)After the last twenty years of research, the occurrence of flexible proteins without a fixed three-dimensional structure are no longer considered to be rare exceptions from the structure-function paradigm. Instead, ... -
Biologisk mångfald i läroböcker i biologi
(2014-10-17)The aim of this thesis is to analyse offered meaning, that is, what and how subject content is communicated to the recipients. In this case the subject content is biological diversity and the communicative artefacts are ... -
Biochemical studies of the essential Clp protease in cyanobacteria and its associated adaptor proteins
(2014-10-03)Proteins are an essential part of all organisms and are involved in many cellular processes. To regulate the function of proteins and facilitate their removal when damaged or otherwise compromised, sophisticated control ... -
Probabilistic modeling in sports, finance and weather
(2014-10-02)In this thesis, we build mathematical and statistical models for a wide variety of real world applications. The mathematical models include applications in team sport tactics and optimal portfolio selection, while the ... -
Light-regulated Development in Arabidopsis
(2014-09-30)Many external and internal factors affect multiple developmental processes in plants. Light is one of the essential factors that regulates various aspects of plant growth and development throughout their life cycle. Through ... -
Hazard assessment of ciprofloxacin, sulfamethoxazole and triclosan for marine periphyton : Ecotoxicology, Pollution Induced Community Tolerance and Co-Tolerance
(2014-09-29)Antibiotics and personal care products are used in large quantities and commonly detected in various environmental compartments. The two antibiotics, ciprofloxacin and sulfamethoxazole, and the personal care product triclosan ... -
A Scholarship Approach to Model-Driven Engineering
(2014-09-26)Model-Driven Engineering is a paradigm for software engineering where software models are the primary artefacts throughout the software life-cycle. The aim is to define suitable representations and processes that enable ... -
Narrativer i förändringsarbete – Från projekt till Athenas plan
(2014-09-24)Planned changes occur constantly in organizations. Most of these change management projects fail to reach decided goals and have limited impact within the organization. An important prerequisite for anchoring changes is ... -
Structural and functional studies of the ATP-dependent Clp proteases in cyanobacteria
(2014-09-17)Proteins are essential in all living organisms and they are involved in a myriad of biological functions. It is vital for cells to have efficient surveillance and quality control systems that ensure damaged proteins are ... -
Utbildning för hållbar utveckling från en lärarhorisont: sammanhang, kompetenser och samarbete
(2014-09-12)Education for sustainable development, ESD, seeks to elucidate complex problems and interdisciplinary, holistic and transformative teaching and learning are described as possible approaches. All teachers, regardless of ...