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Imaging Optodes
(2006) -
Lidar Studies of Tropospheric Aerosols and Clouds
(2008-09-22)An improved description of aerosol and cloud processes is a prerequisite for successful prediction of future climate change. The climate on Earth is controlled by the radiation budget, i.e. the relation between the radiation ... -
Experimental studies of ice particle formation with tropospheric relevance
(2008-11-07)In their fourth assessment report, the Intergovernmental Panel on Climate Change points out the influence of particles suspended in air, known as an aerosol, as the main uncertainty in the understanding of the climate ... -
Kemilaborationens bidrag till förståelse - högskolestudentens perspektiv -
(2008-11-14)Den här studien har som mål att försöka förstå hur laborationen bidrar till att underlätta studenternas kognitiva arbete att förstå teorin ingående i deras första kemikurs på akademisk nivå. Empirin har framförallt sökt ... -
Formation of Skin Sensitizers from Fragrance Terpenes via Oxidative Activation Routes. Chemical analysis, Structure Elucidation and Experimental Sensitization Studies
(2009-01-08)The work presented in this thesis emphasizes the importance of considering oxidative activation in the toxicity assessment of fragrance chemicals. Compounds without contact allergenic properties can be activated either via ... -
Limonene Hydroperoxides in Allergic Contact Dermatitis. Radical Formation, Sensitizing Capacity and Immunogenic Complex Formation.
(2009-04-24)Contact allergy to fragrance compounds is an increasing problem in the western countries today. R-Limonene is one of the most common fragrance compounds; it is used in hygiene products and cosmetics as well as in industrial ... -
Theoretical Investigations of the Role of Ion-Ion Correlations and Ion-Specific Interactions in Electric Double Layers
(2009-09-10)Electric double layers are ubiquitous, arising in some form in almost every situation involving an interface with an aqueous electrolyte solution. In order to gain insight into the behavior of electrolytes and electric ... -
Proton conductivity in acceptor-doped lanthanide based pyrochlore oxides
(2009-11-06)A high interest in developing new materials for SOFC applications in the temperature range of approximately 200–500 degrees C has been growing lately. The lower activation energies for proton (H+) mobility can give higher ... -
Carbon Dynamics in Northern Marginal Seas
(2009-11-27)The marginal seas have, despite their relatively small area, an important role in the global carboncycle. They are largely influenced by carbon and nutrient fluxes from land and a large part of the biological production ... -
Absolute Asymmetric Synthesis
(2010-02-03)Absolute asymmetric synthesis is the synthesis of optically active products from achiral or racemic precursors only. This has generally been regarded as impossible and is relevant in the discussion of the origins of ... -
Improving Drug Discovery Decision Making using Machine Learning and Graph Theory in QSAR Modeling
(2010-02-12)During the last decade non-linear machine-learning methods have gained popularity among QSAR modelers. The machine-learning algorithms generate highly accurate models at a cost of increased model complexity where simple ... -
Samarium(II)-mediated reactions in organic synthesis - method development and mechanistic investigation
(2010-04-07)This thesis describes the development of methods using divalent samarium reagents in organic synthesis. The main focus is placed on functional group reductions, but reductive formation of carbon-carbon bonds has also been ... -
Development and use of optical sensors in modern analytical chemistry
(2010-04-09)A successful long-term high resolution imaging experiment in marine sediments was performed (17 days within the sample; Paper I). The time correlated calibration procedure was evolved to include parametric sigmoidal and ... -
Electrochemical and Enzymatic In Vitro Studies on Reactive Drug Metabolites Synthesis, Characterization and Avoidance
(2010-05-03)ABSTRACT During development of pharmaceuticals, it is essential to as early as possible identify and preferably avoid formation of reactive metabolites and ... -
Experimental and computational investigation of affinity and selectivity factors in CYP2D6 and CYP3A4 mediated metabolism
(2010-09-02)The assessment of ADME properties and metabolic behavior of a drug is central in drug discovery and drug design. The main target for studies of metabolic properties is the Cytochrome P450 (CYP), which is responsible for ... -
Ligand Dependent Regioselectivity in Palladium Mediated Allylic Alkylation
(2010-09-17)In this thesis, different aspects on ligand dependent regioselectivity in palladium mediated allylic alkylation have been studied. It is believed that the regioselectivity is a result of nucleophilic attack trans to ... -
Structure, phase behavior, and dynamics of colloidal systems characterized by strong, short- and moderate-ranged attractions: a computational study
(2010-11-03)Attractions between colloidal particles are often so strong that non-equilibrium behavior results. However, dissolved non-adsorbing polymer can be added to give a weak attraction between particles so that equilibrium phase ... -
Isothiocynates as skin sensitizers. Bioactivation and distribution in skin and lymph nodes
(2010-11-05)Development of contact dermatitis can be caused by electrophilic compounds (haptens) or prohaptens that come into contact with the skin. A prohapten is a compound seemingly harmless at first sight that can be transformed ... -
Algorithms for analysis of NMR projections: Design, implementation and applications
(2011-03-29)With an increasing rate of protein expressions the need for fast protein characterization has become more important. Protein NMR has long been an important contributor for protein characterization; being one of a few ... -
Structure and Function of Aqua(glycero)porins - A Path to Drug Design
(2011-04-05)Membrane proteins are a major class of the drug targets. Rational design of drugs requires knowledge about the structure and function of these proteins. Working with membrane proteins, however, is experimentally challenging ...