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Absolute Asymmetric Synthesis
(2010-02-03)Absolute asymmetric synthesis is the synthesis of optically active products from achiral or racemic precursors only. This has generally been regarded as impossible and is relevant in the discussion of the origins of ... -
Absolute Asymmetric Synthesis
(2011-04-18)Absolute asymmetric synthesis is the synthesis of optically active products from achiral or racemic precursors only. This has generally been regarded as impossible and is relevant in the discussion of the origins of ... -
Algorithms for analysis of NMR projections: Design, implementation and applications
(2011-03-29)With an increasing rate of protein expressions the need for fast protein characterization has become more important. Protein NMR has long been an important contributor for protein characterization; being one of a few ... -
Analysis of phospholipids in cellular membranes with LC and imaging mass spectrometry
(2011-05-20)Imaging mass spectrometry enables the creation of molecule specific images from the surface of a solid sample in vacuum. To solve the issue of bringing single cells into vacuum without altering their native distribution ... -
AQUAPORINS: Production Optimization and Characterization
(2011-05-05)Aquaporins are water facilitating proteins embedded in the cellular membranes. Such channels have been identified in almost every living organism – including humans. They are vital molecules and their malfunction can lead ... -
Carbon Dynamics in Northern Marginal Seas
(2009-11-27)The marginal seas have, despite their relatively small area, an important role in the global carboncycle. They are largely influenced by carbon and nutrient fluxes from land and a large part of the biological production ... -
Chemical and Dermatological Aspects of UV-absorbing Compounds
(2011-09-27)ABSTRACT The sun’s UV radiation is necessary for the existence of life on earth. However, too much UV exposure can lead to the development of skin cancer. Therefore, sunscreens are often used by the general population ... -
Chiral Lithium N,P-amide Complexes. Synthesis, Applications and Structural Studies by NMR and DFT.
(2011-11-28)Enantiospecific synthesis reactions are of intense interest, owing to the increasing request for enantiopure compounds in both research and industry. Lithium amides containing a secondary chelating group are a class of ... -
Colloidal interactions obtained from total internal reflection microscopy measurements and scattering data
(2011-05-18)The scattering of radiation can be used to extract information about the interactions between colloidal (10^{-7}-10^{-3} cm radius) particles suspended in liquids. As colloidal interactions incorporate entropic effects ... -
Conformational Dynamics of Rhodopsins Visualized by Time-resolved Wide Angle X-ray Scattering
(2011-10-27)Rhodopsins are a family of light-sensitive proteins found in the cellular membranes of a wide range of living organisms. These membrane proteins share a common molecular architecture and are able to use light energy ... -
Development and use of optical sensors in modern analytical chemistry
(2010-04-09)A successful long-term high resolution imaging experiment in marine sediments was performed (17 days within the sample; Paper I). The time correlated calibration procedure was evolved to include parametric sigmoidal and ... -
Electrochemical and Enzymatic In Vitro Studies on Reactive Drug Metabolites Synthesis, Characterization and Avoidance
(2010-05-03)ABSTRACT During development of pharmaceuticals, it is essential to as early as possible identify and preferably avoid formation of reactive metabolites and ... -
Experimental and computational investigation of affinity and selectivity factors in CYP2D6 and CYP3A4 mediated metabolism
(2010-09-02)The assessment of ADME properties and metabolic behavior of a drug is central in drug discovery and drug design. The main target for studies of metabolic properties is the Cytochrome P450 (CYP), which is responsible for ... -
Experimental studies of cluster ions containing water, ammonia, pyridine and bisulphate
(2011-10-06)Molecular cluster ions are fascinating subjects of study. Bridging the size gap between molecules and bulk, they often display non-trivial size dependent behaviour and properties. As an example, for some cluster types there ... -
Experimental studies of ice particle formation with tropospheric relevance
(2008-11-07)In their fourth assessment report, the Intergovernmental Panel on Climate Change points out the influence of particles suspended in air, known as an aerosol, as the main uncertainty in the understanding of the climate ... -
Fluxes and transformation of carbon in the Siberian shelf seas under changing environment
(2012-05-16)The Arctic is especially vulnerable to the increased air temperature caused by emissions of greenhouse gases to the atmosphere, carbon dioxide being one of them. In this thesis, both fieldwork and modelling of the East ... -
Formation of Skin Sensitizers from Fragrance Terpenes via Oxidative Activation Routes. Chemical analysis, Structure Elucidation and Experimental Sensitization Studies
(2009-01-08)The work presented in this thesis emphasizes the importance of considering oxidative activation in the toxicity assessment of fragrance chemicals. Compounds without contact allergenic properties can be activated either via ... -
Homochiral Crystals for Selective Synthesis
(2011-04-13)Six new coordination compounds were prepared from monodentate sulfide ligands and copper(I) halides and their crystal structures were determined by single-crystal X-ray diffraction. The aim was to prepare coordination polymers ... -
Hydrolytic Synthesis and Physicochemical Properties of TiO2 Nanoparticles: Fundamentals and Applications
(2012-04-13)Titanium dioxide (TiO2) nanoparticles were synthesized via the hydrolysis of TiCl4 in order to produce clean, surfactant-free oxide surfaces. By controlling the synthesis and aging conditions, stable particles with ...