Vaccinationsvilja hos gravida: en undersökning av vaccination mot kikhosta under graviditeten i Stockholms län.

Abstract

Introduction Pertussis is an acute respiratory infection caused by the bacteria Bordetella pertussis. The infection is highly contagious and can be severe for infants. Vaccination during pregnancy provides the infant with protection during the first months of life, before the infant receives vaccination. In Sweden, vaccination is recommended after week 16 of the pregnancy. Although the vaccine is safe, effective, and free of charge, vaccination coverage varies within Stockholm County. Research question Which factors are associated with the choice to receive or decline pertussis vaccination during pregnancy in Stockholm County? Study participants and methods A quantitative cross-sectional study using surveys was conducted from March 3 to April 10, 2025. Study participants were pregnant from gestational week 25 onwards and registered at midwifery clinics in Stockholm County. Data were analysed using descriptive statistics and logistic regression to identify factors associated with the intention to get vaccinated. Results Eighty-seven people participated in the study. 75% reported that they either planned to get vaccinated against pertussis during pregnancy or had already been vaccinated, while 25% were unsure or did not intend to get vaccinated. Multivariable logistic regression analysis identified significant associations between lower vaccination willingness and: having a native language other than Swedish; responses indicating lack of knowledge or awareness about the disease; uncertainty about or lack of information regarding pertussis vaccination from a midwife/other healthcare personnel and being unsure/not knowing anyone who had been vaccinated against pertussis during pregnancy. Conclusions and Implications This study highlights several factors associated with the participants declining pertussis vaccination during pregnancy in Stockholm County, worth further investigation. A better understanding of these factors may support development of targeted interventions, such as midwife-led vaccination models, information campaigns, education about pertussis risks, and initiatives highlighting positive vaccination experiences. Due to study limitations, general conclusions should be made carefully.