Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet: Recent submissions
Visas titlar 101-120 av 10942
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Development and Applications of Microfluidic Devices for Liver-on-a-Chip Studies
(2021-10-12)Modeling the human physiology in vitro is a challenging task, yet one of importance for the development of drugs and the study of diseases. To better address the complexities of human organs, microfluidic systems called ... -
Computational studies of mutational sequence signatures in cancer genomes
(2021-10-08)Cancer typically forms when mutational processes modify key cancer driver genes, resulting in positive selection and tumor growth. As such, mutational processes are at the core of the disease. Trinucleotide mutational ... -
Periarticular changes in association with osteoarthritis in the hip, knee or shoulder
(2021-10-08)The aim of this thesis was to evaluate the presence of degenerative changes in the periarticular tendons in association with osteoarthritis (OA) in the hip, knee or shoulder. Moreover, changes in bone mineral density (BMD) ... -
Health Information Systems Interoperability: Towards a Managing as Designing Approach
(2021-10-08)Integrated digital healthcare systems promise improved quality public healthcare and patient continued care among others. However, these have been hampered by various challenges including limited data exchanges between ... -
On dental implant failure and patient-related factors
(2021-10-08)Dental implants function as anchorage for dental prostheses. In a small number of cases, osseointegration fails to establish or be maintained around the implants, but the reasons for these failures are not yet fully ... -
The molecular chaperone CCT: Functions beyond folding
(2021-10-07)The chaperonin-containing tailless complex polypeptide 1 (CCT) is a eukaryotic ~1 MDa barrel shaped molecular chaperone, built up by eight distinct subunits and is required for the folding of the abundant cytoskeletal ... -
Mechanisms underlying inflammation, symptoms and quality of life in ulcerative colitis
(2021-10-06)A substantial proportion of patients with ulcerative colitis (UC) in remission demonstrate gastrointestinal (GI) symptoms, despite the absence of ongoing inflammation in the colon. The underlying mechanisms of these symptoms ... -
Effect of Probiotics on Caries-related Variables
(2021-10-05)In relation to the caries disease, the aims of this thesis were to investigate the effect of probiotic drops on different caries-related variables in vivo (Papers I & III), on interference capability and genetic response ... -
Le sommeil dans À la recherche du temps perdu de Marcel Proust: une étude intertextuelle
(2021-10-05)This thesis examines the intertextual aspects of the sleep motif in À la recherche du temps perdu by Marcel Proust. Literary scholars and theorists have generally iden- tified two dominant ways of depicting sleep in ... -
Effects of carbon dioxide and ozone on wheat crop yield and grain quality
(2021-10-05)Atmospheric concentrations of carbon dioxide (CO2) and ozone (O3) have steadily increased since the industrial revolution. CO2 and O3 directly affect plant physiology, CO2 being an essential substrate for photosynthesis, ... -
Adaptation of ventricular repolarization to heart rate change in humans
(2021-10-01)Background: Life-threatening cardiac rhythm disturbances and sudden death are common manifestations of heart disease. Disturbances in electrical recovery (ventricular repolarization; VR) are important mechanisms behind ... -
Predictors of survival in cardiac arrest
(2021-10-01)Cardiac arrest (CA) refers to the cessation of cardiac function. Survival is around 30% for in-hospital cardiac arrest (IHCA), and 10% for out-of-hospital cardiac arrest (OHCA). Many factors influence survival, ranging ... -
Neutrophil recruitment in periodontal disease
(2021-10-01)Neutrophils are the first immune cells to arrive in infected or injured tissues, where they engulf microbes and clean up cell debris. Periodontitis is one of the typical symptoms of both neutropenia and defect neutrophil ... -
Treatment of early prostate cancer - reducing side effects without jeopardizing cure
(2021-09-29)The overall aim of this thesis is to gain further knowledge of how surgical choices affect the outcome for patients undergoing radical prostatectomy for early prostate cancer including preoperative evaluation and long-term ... -
Community stress exposure: Youth externalizing behavior and parenting in cultural context
(2021-09-28)The aim of this thesis was to examine the process by which families respond to community-wide stressors in different cultural contexts. Each quantitative study within this thesis investigated the role of parenting behaviors ... -
lntrafractional motion effects during stereotactic body radiation therapy of lung tumors
(2021-09-24)Abstract: Patient shifts and tumor motions occurring during stereotactic body radiation therapy (SBRT) have been analyzed to determine the related effects on the delivered dose. Methods: 4-dimensional computed tomography ... -
Optimization of first-line anti-tuberculosis therapy in patients co-infected with HIV
(2021-09-24)Every year over one million people die from tuberculosis. People infected with HIV are significantly more vulnerable to tuberculosis, which is the leading cause of HIV-associated death. The first-line treatment for ... -
Generative comics - A computational approach to creating comics material
(2021-09-24)Digital storytelling can be employed as a tool that incorporates human creativity with technology. It synthesizes multimedia based elements to create engaging stories and compelling narratives. To this end, this research ... -
Teaching with Digital Mathematics Textbooks - Activity Theoretical Studies of Data-Driven Technology in Classroom Practices
(2021-09-24)The introduction of digital textbooks, with data-driven functionalities, is a recent trend in mathematics education challenging established teaching practices. This new technology represents a key shift as student datasets ... -
Responsibilisering - En studie av assistanssektorns kvasimarknad
(2021-09-21)De senaste decenniernas valfrihetsreformer i välfärden har föregåtts av argument om att valfrihet frigör brukare genom att kontrollen över välfärdstjänster överlåts åt de som utnyttjar dem. Denna avhandling behandlar en ...