Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet: Recent submissions
Visas titlar 421-440 av 10942
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A Hybrid Operating Room in the Making - Coordinating the lntroduction and Use of New Technology
(2020-05-11)New technologies are often introduced hoping to achieve cost reductions, efficiency improvements, and product/service quality increases. Early researchers have often focused on these hopes and how existing organizational ... -
Network modeling and integrative analysis of high-dimensional genomic data
(2020-05-07)Genomic data describe biological systems on the molecular level and are, due to the immense diversity of life, high-dimensional. Network modeling and integrative analysis are powerful methods to interpret genomic data. ... -
On tissue engineering of pig, human, and non-human primate tissues
(2020-05-07)Background: Demand for donor organs for transplantation has been increasing every year more than the actual supply of suitable donor organs. One of the major problems associated with allogeneic transplantation includes ... -
Cardiac arrest with emphasis on comorbidity and choice of treatment in acute coronary syndrome in the elderly
(2020-05-07)Background and aim: More data is required on survival and neurological outcome after in-hospital cardiac arrest (IHCA) in the elderly. The influence of comorbidity is often neglected in cardiac arrest research, particularly ... -
Primordial radionuclides in pit lakes in Sweden
(2020-05-07)In Sweden, there are many pit lakes, originating from limestone quarries and metal mines, with unknown status in regard to the activity concentration of radionuclides. Such knowledge is generally available only for pit ... -
Natural course and long-term prognosis in idiopathic Normal Pressure Hydrocephalus - the effect of delayed surgery and clinical factors on outcome and survival
(2020-05-07)Idiopathic Normal Pressure Hydrocephalus, iNPH, causes gait and balance difficulties, urinary incontinence and cognitive decline in mainly older persons and is treatable by insertion of a cerebrospinal fluid diverting ... -
Recurrent infection with Extended-Spectrum Beta-Lactamase (ESBL) -producing Enterobacteriaceae
(2020-05-05)Infections with Extended-Spectrum Beta-Lactamase (ESBL)-producing Enterobacteriaceae (EPE) are increasing globally. The most common EPE are the gut pathogens Escherichia coli (ESBL-E. coli) and Klebsiella pneumoniae (ESBL-K. ... -
Development and dynamics of the normal gut microbiota
(2020-05-05)Altered gut microbiota configurations have been linked to human diseases. To identify mechanistic links between altered gut microbiota and disease states, definitions of the healthy gut microbiota need to be established. ... -
Why the pond is not outside the frog? Grounding in contextual representations by neural language models
(2020-05-05)In this thesis, to build a multi-modal system for language generation and understanding, we study grounded neural language models. Literature in psychology informs us that spatial cognition involves different aspects of ... -
Dynamics and Structure of Negative Ions - Photoinduced double detachment on nano- and femtosecond time scales
(2020-05-05)The goal of the presented work is to investigate double detachment of negative ions on nano- and femtosecond time scales. I have performed three types of experiments. Femtosecond time resolved pump-probe experiments ... -
Val-omröstning-styrning. En etnografisk studie om intentioner med, villkor för och utfall av barns inflytande i förskolan
(2020-05-04)This thesis takes its point of departure in an interest in exploring how children’s participation is expressed in policy texts as well as in preschool practice. Participation can be viewed as a discourse of considerable ... -
The construction, analysis and validation of mechanistic mathematical models of protein kinetics in the context of replicative ageing in budding yeast
(2020-05-04)Mathematical modelling constitutes a forceful tool for elucidating properties of biological systems. Using theoretical approaches in combination with experimental techniques it is possible to study specific molecular aspects ... -
Understanding the molecular mechanisms of bile acid receptor activation for the treatment of human liver disease
(2020-04-30)Farnesoid X receptor (FXR) is a nuclear transcription factor that is activated by bile acids and regulates bile acid homeostasis, glucose and lipid metabolism. FXR activation by a ligand has been identified as a therapeutic ... -
Decellularization as a method to generate a new generation of vascular grafts
(2020-04-29)Decellularization of blood vessels is a technique to remove cells from the extracellular matrix (ECM), which can be used as a vascular graft for peripheral or coronary blood vessel bypass surgery. This thesis focuses on ... -
Regulators of Membrane Fluidity
(2020-04-29)Caenorhabditis elegans PAQR-2 (a homolog of the mammalian AdipoR1 and AdipoR2 proteins) and IGLR-2 (homolog of the mammalian LRIG proteins) form a complex at the plasma membrane that regulates fatty acid desaturation to ... -
Release and Clearance Mechanisms of Cardiac Troponin
(2020-04-28)Myocardial infarction (MI) is often suspected when a patient presents with chest pain. MI is defined as cardiac necrosis due to ischemia, most often mediated through impaired coronary perfusion. Cardiac necrosis results ... -
Virtual reality based kinematics for assessment of post-stroke upper limb function
(2020-04-28)The main scope of this thesis was to develop a method for assessing the upper limb sensorimotor function following stroke using virtual reality-based technique. The studies reported in this thesis included 67 individuals ... -
Depression among Swedish 70-year-olds - Sex differences from a gender perspective
(2020-04-28)Depression is one of the leading causes of global burden of disease. Due to increased life expectancy, late-life depression is an escalating public health issue. The prevalence is reported to be almost twice as high among ... -
Congenital Heart Disease, Type 1 and Type 2 Diabetes Mellitus
(2020-04-28)Worldwide, 1% of all live born children are born with a congenital heart disease (CHD) and currently >95% reach adulthood due to better diagnostics and medical care. At the same time, Diabetes Mellitus (DM), type 1 (T1DM) ... -
Investigating the role of Class-1 Phosphoinositide 3 Kinases (PI3Ks) in insulin signaling and obesity
(2020-04-28)Obesity and obesity related diseases such as type 2 diabetes, cardiovascular disorders, and different types of cancer are leading causes of mortality and morbidity in modern society. However, the mechanism that links obesity ...