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Health economic aspects of stroke: stroke prevention and effects on spouses' healthcare consumption and income
(2023-01-23)The overall aim of this thesis was to investigate two health economic aspects of stroke: (i) the clinical and cost-effectiveness of stroke prevention with left atrial appendage occlusion (LAAO) among persons with atrial ... -
The long-term effects of obstetrical anal sphincter injury on pelvic floor function
Background: As women live longer, the long-term effects of childbirth may negatively affect their quality of life and professional careers. Aim: This thesis investigates the long-term effects of vacuum extraction (VE) ... -
Markers and mechanisms of abnormal neurovascular development in the preterm infant
Background: The extremely preterm infant is at risk of lifelong neurodevelopmental impairments due to brain injuries or abnormal neurovascular development. Mechanisms are largely unknown and biomarkers for adverse outcomes ... -
Outcomes and Experiences of a Fast Track - A direct admission process from ambulance to stroke unit for patients not eligible for acute intervention
Background Stroke is a serious medical condition, and the time before acute intervention and care at stroke units is crucial. People who suffer from a stroke and are not eligible for stroke alert are often transported to ... -
Factors of importance for work productivity in Irritable Bowel Syndrome
Disorders of gut-brain interaction (DGBI) are highly prevalent in the general population, and irritable bowel syndrome (IBS) is one of the most common DBGI. Having IBS, and many of the DGBI, can impact work life. However, ... -
Advances in MRI based radiation therapy - Bringing MRl-only and multiparametric methods towards clinical applications
MRI data have the advantage of being excellent in soft tissue contrast, therefore having an increasing imaging role in external radiation therapy (RT). Lately, attention has been directed towards MRI-only workflows, with ... -
Septoplasty-predicting the outcome
Septoplasty is one of the most common surgical procedures at ENT clinics around the world. The reason for undergoing a septoplasty is nasal airway obstruction (NAO) that does not respond to any other treatment. The most ... -
Pain, gender norms and psychosocial resources. A critical appraisal of taken for granted ideas on men and women with pain
Background: Gender norms concerning pain are important to consider as they might lead to unequal treatment of men and women in health care. Aim: The overall aim of this thesis was to explore and describe gender norms ... -
On ankle fractures
Ankle fractures range from simple avulsions to complex injuries and the treatment options are numerous. Sweden has no national guidelines regarding the management and treatment of ankle fractures, leaving these choices up ... -
Stigma and socioeconomic outcomes in epilepsy
(2022-12-21)Epilepsy influences all aspects of life. While the treatment of seizures is the natural starting point in epilepsy care, social aspects of epilepsy need consideration for successful outcomes. The purpose of this doctoral ... -
Endogenous sex hormones and cardiometabolic risk factors – population-based studies within the Skaraborg Project
(2022-12-21)Cardiovascular diseases are the major contributors to mortality in Sweden and globally. Men have a higher incidence of cardiovascular diseases compared to women, until women reach the menopause. Levels of sex hormones ... -
Surgical treatment strategies of chronic subdural hematoma
(2022-12-05)Background: A subdural collection of old blood is called a chronic subdural hematoma (cSDH). A cSDH of sufficient volume becomes symptomatic and neurosurgical evacuation is then necessary. The recurrence rate (5-21%) after ... -
Understanding the genetic architecture of fatty liver disease
(2022-11-29)Non-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease, ranging from simple steatosis to more severe conditions, namely non-alcoholic steatohepatitis (NASH), liver fibrosis, cirrhosis, ... -
Nurses' psychosocial work environment, parental needs and communication at the neonatal intensive care unit
(2022-11-25)Background. Parents with an infant in the neonatal intensive care unit (NICU) often experience great emotional distress. They are dependent on staff for help in caring for and relating to their infant. Nursing staff who ... -
Female sex hormones and health outcomes in women with specific focus on asthma
(2022-11-25)In humans, gender differences exist across a wide spectrum of diseases. For instance, women are more likely to develop Sjogren’s syndrome, systemic lupus erythematosus, and autoimmune thyroid disease compared to men. On ... -
Novel immunotherapies for metastatic uveal melanoma - From bench to clinical biomarkers
(2022-11-25)Immunotherapy has revolutionized cancer treatment, with durable long-term effects in a proportion of patients. However, in around half of these patients, there are little to no effects. Patients with metastatic uveal ... -
Studies of molecular features and novel prognostic biomarkers of cutaneous melanoma
(2022-11-22)Cutaneous malignant melanoma is a highly heterogeneous disease. Immunotherapy has revolutionized the treatment of stage IV disease and is now successfully administered as adjuvant treatment in stage III and soon in stage ... -
Continued follow-up care - during transition and transfer of young people with congenital heart disease
(2022-11-22)Although life-long follow-up care and transfer from paediatric to adult facilities are recommended for most young people with congenital heart dis-ease, a substantial proportion present with discontinued follow-up care, ... -
Acquired epilepsy in Multiple sclerosis: a nationwide register-based investigation into prognosis and treatment
(2022-11-22)The prevalence of epilepsy in persons with multiple sclerosis (MS) is thrice that of the general population. The association between epilepsy and MS prognosis and its management are however largely unknown. The prevalence ...