Sahlgrenska Academy / Sahlgrenska akademin: Recent submissions
Visas titlar 641-660 av 2677
-
Adherence to lipid-lowering medications and cardiovascular disease prevention in type 2 diabetes mellitus
(2018-11-07)Background and aims: Globally, cardiovascular disease (CVD) is the major cause of death among patients with type 2 diabetes mellitus (T2DM). Improved control of LDL cholesterol with lipid-lowering medications and patients’ ... -
Targeted radiotherapy in metastatic neuroendocrine tumours: clinical and experimental studies
(2018-11-06)ABSTRACT Neuroendocrine tumours (NET) often present at a metastatic stage, which diminishes the possibility for curative surgery. Peptide receptor radiotherapy (PRRT) with 177Lu-DOTATATE targets somatostatin receptors, ... -
Influence of serotonin on anxiety-like behavior in rat
(2018-11-05)It is well-established that serotonin is involved in the regulation of mood and behaviour, partly implied by the therapeutic effect of prolonged treatment with selective serotonin reuptake inhibitors (SSRI) on mood and ... -
Diffuse large B-cell lymphoma - proteomic and metabolomic studies on prognosis and treatment failure
(2018-11-05)Abstract Background and aim: Every year almost 600 patients in Sweden are diagnosed with diffuse large B-cell lymphoma (DLBCL), the most common lymphoma, and with immunochemotherapy, approximately 60 % are cured. Yet, for ... -
Influencing factors of orthodontic tooth movement and root resorption, and evaluation of its radiographic diagnostic means
(2018-11-05)Aims: To investigate whether patient- or tooth-related factors like jaw location or intra- and interarch obstacles influence the amount of orthodontic tooth movement and orthodontically induced root resorption, and to ... -
Genetic factors affecting pregnancy duration in humans
(2018-11-01)This thesis investigates the mechanisms behind human pregnancy duration. Too short gestation is a direct cause of perinatal, neonatal, and infant mortality. Deviation from normal pregnancy length is also associated with a ... -
Human growth patterns - with focus on pubertal growth and secular changes
(2018-10-30)Introduction: Human growth is a dynamic process, an indicator of health and disease. Previous used growth models have been limited in describing the pubertal growth spurt. ... -
Host-Virus Interactions in Asthma and COPD
(2018-10-26)Asthma and chronic obstructive pulmonary disease (COPD) are associated with periods of worsened symptoms, known as exacerbations. Severe exac-erbations can result in hospitalisation, irreversible decline of the disease and ... -
Timely treatment in stroke and TIA
(2018-10-26)In acute stroke, the effect of both acute treatments and secondary prevention is timedependent. Patients´ delay is an important obstacle to acute recanalization therapy for stroke. To decrease this delay, a stroke ... -
Collaborative challenges in integrated care: Untangling the preconditions for collaboration and frail older people's participation
(2018-10-26)Introduction: Frail older people often have comprehensive and complex care needs involving different caregivers and professionals. Deficits in integrated caretaking often result in hospital readmission. Aim: The aim of ... -
Women's and Men's Health care utilisation from a cost perspective
(2018-10-23)The aim of this thesis was to explore sex differences in health care utilisation and costs (i) in a region in Sweden, (ii) in treatment of dialysis patients across the region, and (iii) in the treatment of specified ... -
Early stage inflammation and cancer as reflected in the gastrointestinal mucus composition: implications for diagnosis, prognosis and pathogenesis
(2018-10-23)Mucus covers our inner interfaces towards the environment, providing protection while enabling vital interaction with the outside world. The mucus is built around mucin proteins, which are important for our defences against ... -
Nutritional metabolomics: The search for dietary exposure variables
(2018-10-19)To establish associations and causation between diet and health, objective and reliable methods are needed to measure dietary exposure. Metabolomics provide an unbiased tool for exploring the modulation of the human ... -
On oxytocin and social behavior
(2018-10-19)Complex social cognitive processes underlie social behavior. Oxytocin has long been recognized as crucial in social behavior in animals, but its role in regulating human social cognition and behavior is less clear, ... -
Er:YAG laser in dentistry. Patients’ experiences and clinical applicability
(2018-10-12)Abstract Er:YAG laser in dentistry. Patients’ experiences and clinical applicability Roxana Sarmadi, Department of Cariology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Box 450, SE-405 30 ... -
Colonic mucus structure and processing
(2018-10-05)The mucus layer covering the colonic epithelium creates a crucial first line of defense against the gut residing bacteria. Several lines of evidence suggest that a functional mucus layer is essential for health. For example, ... -
Cerebrospinal fluid peptidomics: discovery of endogenous peptides as biomarkers of Alzheimer's disease
(2018-10-02)Neurodegenerative diseases (NDs), the most prominent example of which is Alzheimer’s disease (AD), has turned out to be among the greatest challenges for modern medicine. Common characteristics of NDs involve the aggregation ... -
Vitamin D in Somali women living in Sweden
(2018-10-02)Introduction: Sunlight is the major source of Vitamin D synthesis. Information regarding vitamin D, bone status and general health in Somali women living in Sweden is limited. Vitamin D binding protein (DBP) is the major ... -
Capturing the experience of health among persons aging in a migration context - Health promotion interventions as means to enable health and occupations in daily life
(2018-09-28)Aim: The overall aim of this thesis was to increase our understanding of health in everyday life among older persons aging in migration, and to evaluate the outcome of a health promotion intervention on sense of coherence, ... -
Redox reactions in cancer: impact and regulation
(2018-09-28)The reduction-oxidation (redox) reaction involves a change in the oxidation state of molecules where a molecule that donates an electron is oxidized and a molecule that accepts an electron is reduced. The NADPH oxidase of ...