Institute of Biomedicine / Institutionen för biomedicin: Recent submissions
Visas titlar 321-328 av 328
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Oxidant-induced cell death in lymphocytes: mechanisms of induction and resistance
(2007-04-16)Reactive oxygen species (oxidants, oxygen radicals) produced by the phagocytic NADPH oxidase have pivotal roles in immunity. Patients lacking a functional NADPH oxidase suffer from chronic granulomatous disease, which is ... -
Analysis of Binding Events and Diffusion in Living Cells
(2007-03-06)It is well known that diffusion is the main mode of transport in living cells, but the consequences of diffusion in a complex cellular environment are not generally appreciated. In this thesis, we have investigated several ... -
Computational identification of non-coding RNAs
(2007-01-12)A large amount of genomic information is now becoming available. Suitable bioinformatic tools to organize and analyze this vast amount of information are therefore important. In the case of protein genes, the majority of ... -
Crisis in Energy Metabolism - Mitochondrial Defects and a New Disease Entity
(2006-12-08)Impairment of energy metabolism may be associated with severe implications for affected individuals since all fundamental cell functions are energy-dependent. Disorders of energy metabolism are often genetic and associated ... -
Blood Culture Negative Endocarditis
(2006-12-05)The lethal disease infective endocarditis (IE) is caused by microorganisms that attack heart valves. Early diagnosis and identification of the causative agents are important for the choice of treatment. Optimal treatment ... -
Mass spectrometry for comparative proteomics of degenerative and regenerative processes in the brain
(2006-12-01)Biological processes involve changes at the protein level. Proteomics aims to determine protein changes from a normal state, to measure for instance recovery or disease progression. Mass spectrometry is the most important ... -
Interpretation of diagnostic information given patient characteristics
(2006-10-20)The aim with this thesis was to describe, exemplify and develop theory for reference values and diagnostic tests, especially focusing on the variability between individuals. To facilitate interpretation of medical information ... -
Genetic and molecular regulation of epithelial tube morphogenesis
(2006-09-29)Networks of epithelial tubes, such as the vertebrate lung, kidney and vascular system, enable transport of gases and nutrients to all tissues in the body. These tubes are built up by a single layer of polarized epithelial ...