Institute of Neuroscience and Physiology / Inst för neurovetenskap och fysiologi: Recent submissions
Visas titlar 241-260 av 437
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Att vara agent i sitt eget liv - Hur självbestämmande kan förstås, uppfattas och utvärderas i en kontext av sköra äldre personer
(2014-02-21)Syfte Det övergripande syftet med avhandlingen var att definiera och beskriva självbestämmande i relation till sköra äldre personer, instrumentutvärdering för att skatta äldre personers självbestämmande samt utvärdera ... -
The role of the human C-tactile system in affective somatosensation and pain
(2014-02-21)Affective touch perception in humans is a complex construct of input from mechanoreceptive afferents, current homeostatic state and contextual factors. Previously, a relationship has been identified between the pleasantness ... -
Successful ageing with a focus on fitness and physical activity: population-based studies of 75-year-olds
(2014-01-27)Background: Life expectancy increased dramatically during the 20th century and is still increasing in many parts of the world. In view of population ageing, the health and functioning of older persons and factors that ... -
Quantitative neuroproteomics for biomarker discovery in Alzheimer's disease
(2014-01-17)Alzheimer’s disease (AD) is the most common form of dementia characterized by amyloid plaques and neurofibrillary tangles in the brain. Novel biomarkers for AD are needed that reflect disease progression and could identify ... -
Predictors of long-term outcome after severe traumatic brain injury
(2013-12-20)Aim: A complex interaction between several factors may influence and explain the variance in outcome after traumatic brain injury (TBI). The overall aim of this thesis was to explore, in individuals with severe TBI, the ... -
Mild intellectual disability: Diagnostic and outcome aspects
(2013-11-29)The aim of the thesis was to describe mild intellectual disability (ID) from various neurodevelopmental and neuropsychiatric perspectives in children and young adults. Paper I The objective of the first paper was to ... -
Optimization of HIV therapy in patients co-infected with tuberculosis: a pharmacogenetic and pharmacokinetic study of efavirenz in Rwandan adult patients undergoing HIV and tuberculosis co-treatment
(2013-11-27)Tuberculosis (TB) is the most common opportunistic infection among people infected with human immunodeficiency virus (HIV). The co-management of HIV/TB co-infection is prone to multiple drug-drug interactions. In addition, ... -
Assessment of intelligibility in children
(2013-11-22)Aim: The overall aim of this thesis was to investigate different aspects of intelligibility in children and to develop reliable and valid methods for assessment. Method: Initially, four assessment methods were studied: ... -
Fish and meat intake during pregnancy. The effects on metabolism, bone and body compostition
(2013-11-22)ABSTRACT Fetal programming occurs when nutrients affect the DNA during fetal development and alters the fetus’ genetic make-up. In connection with increasing obesity prevalence focus has been on dietary fats and fatty ... -
Development and validation of upper extremity kinematic movement analysis for people with stroke. Reaching and drinking from a glass.
(2013-11-18)Kinematic analysis is a powerful method for objective assessment of movement performance, and is increasingly employed as outcome measure after stroke. The number of studies investigating natural, goal-oriented daily tasks ... -
Irradiation-induced injury to the juvenile brain -Roles of sex and inflammation
(2013-11-14)Radiotherapy is commonly used in the treatment of pediatric malignancies, but unfortunately it is associated with negative side effects, both long-term and short-term. Negative side effects following cranial irradiation ... -
ESSENCE: Child and Adults Studies of Verbal and Nonverbal Skills in ASD and ADHD
(2013-11-14)Aim: Longitudinal analysis of verbal and nonverbal deficits and skills and their contribution to clinical presentation in children and adults with ESSENCE/Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical ... -
Autism in preschoolers: Assessment, diagnostic and gender aspects
(2013-11-13)Background: Very early assessment of young boys and girls with suspected autism spectrum disorders (ASD) is widely advocated, but knowledge is limited. Aims: Evaluate methods used in assessment of young children with ... -
The neurovascular niche after irradiation to the developing brain
(2013-11-11)Radiotherapy is commonly used in the treatment of pediatric brain tumors but is unfortunately associated with debilitating negative effects, such as impaired memory and learning. Historically, vascular damage following ... -
Effects of epidermal growth factor on adult neural stem cells
(2013-11-04)In the adult brain neural stem cells are present in two discrete regions; the hippocampus and the subventricular zone (SVZ). The environment surrounding the stem and progenitor cells, the neurogenic niche, is integral for ... -
The role of the complement system in ischemic stroke and neural plasticity
(2013-10-29)Evidence from experimental animal studies suggests that complement activation in the brain is a “double-edged sword” as it exerts beneficial or detrimental effects depending on the context. Here, we assessed whether ... -
Parkinson's disease and motor function - a validation of the PLM method
(2013-09-27)Aim: To validate the Posturo-Locomotor-Manual (PLM) test, an objective movement measurement system designed to measure movement disability in patients with Parkinsonism. Method: The reliability of the PLM test was determined ... -
Small diameter afferent stimulation and its effect on behavior in humans
(2013-09-11)Sensation and behavior are linked dimensions in human lives. Experiencing a gentle caress from a loved one is very different than getting our hand burnt on a hot stove. However both those stimuli are signaled in small ... -
Vitamin D in women of reproductive age and during pregnancy - Focus on intake, status and adiposity
(2013-08-28)Vitamin D is attained either through synthesis in the skin by sun exposure or through diet. Vitamin D status is important for skeletal health but optimal vitamin D status may also be important in the development of other ...