Institute of Neuroscience and Physiology / Inst för neurovetenskap och fysiologi: Recent submissions
Now showing items 181-200 of 437
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Self-reported activity and participation in persons with haemophilia living in Sweden
(2016-08-30)Background: Haemophilia is a hereditary disease caused by deficiency of clotting factor VIII or IX. Recurrent joint bleeding episodes can lead to haemophilia arthropathy, a condition affecting daily activities and participation ... -
The role of microglia in Alzheimer's disease - Investigating mechansims regulating amyloid-β clearance
(2016-05-31)Alzheimer’s disease (AD) is the most common form of dementia today. The disease is characterized by the presence of amyloid plaques and neurofibrillary tangles in the brain, accompanied by a progressive neurodegeneration ... -
Epidemiology of Normal Pressure Hydrocephalus - Prevalence, Risk Factors, Diagnosis and Prognosis
(2016-05-31)The number of older persons and individuals with cognitive impairment is expected to increase dramatically in most parts of the world. It is therefore important to learn more about disorders that affect cognition. Idiopathic ... -
Studies on new pharmacological treatments for alcohol dependence - and the importance of objective markers of alcohol consumption
(2016-05-26)This thesis will guide you through three randomized controlled trials (RCT) on three pharmacotherapies for alcohol dependence; the antidepressant drug mirtazapine, the smoking cessation drug varenicline and the glycine-uptake ... -
Intracranial Arachnoid Cysts. Epidemiology, Morphology and Surgical Outcome
(2016-05-13)Background: Intracranial arachnoid cysts (AC) are malformations of the arachnoid membrane. They may cause symptoms, either by obstruction of the CSF flow or by compression of adjacent neural tissues. The aim of this thesis ... -
Asperger syndrome in males over two decades
(2016-05-13)● BACKGROUND: Not much is known about the long-term outcome of Asperger syndrome (AS). The first set of diagnostic criteria was published in the late 1980’s. Research on other normal range IQ Autism Spectrum Disorders (ASD) ... -
Creating opportunities for cultural awareness in occupational therapy: An example from Latin America
(2016-05-09)Aim: to explore how awareness of cultural issues is being applied within occupational therapy to address some of the challenges relating to professional education and practice. Methods: In Study I an integrative literature ... -
Sex steroids and social behavior: from mouse to human
(2016-04-11)Social behavior is a classification of various behaviors such as sexual behavior, aggressive behavior, social memory and sociability. These behaviors are under the regulation of the brain, and the sex steroids influence ... -
The dynamic nature of participation - Experiences, strategies and conditions for occupations in daily life amongst persons with late effects of polio
(2016-02-26)Aim: The overall aim of this thesis was to explore the conditions for daily occupations, and how these are reflected in the daily lives of people with the late effects of polio. Four studies (studies I–IV) are included in ... -
Autism spectrum disorders - first indicators and school age outcome
(2016-02-10)Background: Studies of early indicators, diagnostic stability and outcome at mid-school age in children referred early in life for a suspected autism spectrum disorder (asd) have been few. Aims: To examine early indicators ... -
IL-6 and GLP-1 in body fat regulating parts of the CNS in healthy mice
(2016-01-29)It has previously been shown that mice lacking interleukin-6 (IL-6) develop mature onset obesity. The weight-suppressing effects of IL-6 have been assumed to be exerted at a central level, as supported by the fact that ... -
Active Ageing a Path towards Ageing Well. Physical Functioning, Physical Activity, Falls Self-Efficacy and Social Participation in Community-Dwelling Elderly
(2016-01-21)The overall aim of this thesis was to study factors of importance for active ageing with a focus on physical functioning, physical activity, falls self-efficacy, health-related quality of life and social participation in ... -
Fine motor timing ability - A study of syllable repetition and finger tapping in adults with developmental stuttering or Parkinson's disease compared with healthy adults
(2016-01-19)Aim and methods: The overall aim of this thesis was to explore the fine motor timing ability as manifested by speech motor and fine hand motor activity in persons with developmental stuttering or Parkinson’s disease, and ... -
Aspects on Function in Age-Related Macular Degeneration
(2016-01-08)Age-related macular degeneration (AMD) is one of the leading causes of severe visual loss among persons ≥ 60 years. AMD can be categorized in one of three stages: early, intermediate, or late. In early AMD visual symptoms ... -
Upper extremity functioning during the first year after stroke
(2015-12-17)The overall aim of this thesis was to investigate upper extremity functioning during the first year after stroke from different perspectives. Methods. All patients with first ever stroke, admitted to a stroke unit within ... -
Neuromodulation of hippocampal single cell- and network activity by human cerebrospinal fluid
(2015-11-24)Neuromodulation is a key process determining the function of central neurons. The brain extracellular fluid contains numerous neuromodulatory substances (neuromodulators), but how they collective influence neuronal activity ... -
Molecular and physiological regulation of adiponectin exocytosis in white adipocytes
(2015-11-23)In this thesis we have investigated the mechanisms of white adipocyte regulated exocytosis in health and disease, with a special focus on adiponectin. We have applied a combination of electrophysiological membrane capacitance ... -
Blood biomarkers for traumatic brain injury
(2015-11-13)Traumatic brain injury (TBI) is the major cause of death and disability following blunt head trauma. The term mild TBI (mTBI) or concussion are used interchangeably in the literature. Concussion or mTBI is recognized as a ... -
Effects of dietary fatty acids on the immune system
(2015-11-11)Sepsis is a deadly disease with an increasing incidence worldwide. Today, antimicrobials are the only effective pharmacological treatment. At the same time, bacteria, the pathogens behind most cases of sepsis, are becoming ... -
Lithium protects the juvenile brain from ionizing radiation
(2015-10-14)Radiotherapy used in the treatment of brain tumours in children results in a range of cognitive dysfunctions that impact the quality of life in the surviving population. In past decades, great strides were made in understanding ...