Institute of Medicine / Institutionen för medicin: Recent submissions
Now showing items 101-120 of 1073
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Obesity, Weight Loss and Cardiovascular Risk
(2020-05-26)Background: The global prevalence of obesity is on the rise, contributing to increased incidence and prevalence of cardiovascular morbidity and mortality. Obesity has adverse effects on cardiac structure and function, ... -
Cardiac arrest with emphasis on comorbidity and choice of treatment in acute coronary syndrome in the elderly
(2020-05-07)Background and aim: More data is required on survival and neurological outcome after in-hospital cardiac arrest (IHCA) in the elderly. The influence of comorbidity is often neglected in cardiac arrest research, particularly ... -
Development and dynamics of the normal gut microbiota
(2020-05-05)Altered gut microbiota configurations have been linked to human diseases. To identify mechanistic links between altered gut microbiota and disease states, definitions of the healthy gut microbiota need to be established. ... -
Understanding the molecular mechanisms of bile acid receptor activation for the treatment of human liver disease
(2020-04-30)Farnesoid X receptor (FXR) is a nuclear transcription factor that is activated by bile acids and regulates bile acid homeostasis, glucose and lipid metabolism. FXR activation by a ligand has been identified as a therapeutic ... -
Decellularization as a method to generate a new generation of vascular grafts
(2020-04-29)Decellularization of blood vessels is a technique to remove cells from the extracellular matrix (ECM), which can be used as a vascular graft for peripheral or coronary blood vessel bypass surgery. This thesis focuses on ... -
Congenital Heart Disease, Type 1 and Type 2 Diabetes Mellitus
(2020-04-28)Worldwide, 1% of all live born children are born with a congenital heart disease (CHD) and currently >95% reach adulthood due to better diagnostics and medical care. At the same time, Diabetes Mellitus (DM), type 1 (T1DM) ... -
Investigating the role of Class-1 Phosphoinositide 3 Kinases (PI3Ks) in insulin signaling and obesity
(2020-04-28)Obesity and obesity related diseases such as type 2 diabetes, cardiovascular disorders, and different types of cancer are leading causes of mortality and morbidity in modern society. However, the mechanism that links obesity ... -
Underlag för information om covid-19 vid trångboddhet och flergenerationsboende
(Samhällsmedicin och folkhälsa, Göteborgs universitet, 2020-04-23)Trångboddhet är en välkänd riskfaktor för luftvägsinfektioner. Att bo flera generationer tillsammans under trånga förhållanden gör det särskilt svårt att skydda de äldre som löper ökad risk för svår covid-19 infektion. De ... -
Cardiovascular disease in patients with congenital heart disease
(2020-04-23)Background: Today, about 95% of children with congenital heart disease (CHD) survive into adulthood and the survival in patients with CHD has increased considerably during the last decades. With increasing age, patients ... -
Covid-19 i trångbodda förorter och på äldreboende - Samverkande strukturella faktorer?
(Samhällsmedicin och folkhälsa, Göteborgs universitet, 2020-04-16)Syftet med denna studie är att kartlägga olika strukturella förhållanden i Stockholm, Göteborg och Malmö som hypotetiskt skulle kunna bidra till den ökade Covid-19 frekvensen i vissa förorter. Kartorna visar att trångboddhet ... -
Aspects of heart failure development and prevention in women
(2020-04-15)Heart failure (HF) is a severe progressive condition. Women more often are older and suffer from heart failure with preserved ejection fraction (HFpEF), contrasting to men who more often are younger and suffer from heart ... -
Immunological, vascular and metabolic actions of androgens
(2020-03-10)Men have higher prevalence of cardiovascular disease (CVD) but lower risk of autoimmune disorders than women. The actions of sex steroids may be involved in the sexual dimorphism of these diseases. Although testosterone, ... -
Prevalance and prevention of sexually transmitted viral infections in the Bolivian Amazonas
(2020-03-05)This thesis investigates the prevalence of sexually transmitted viral infections in women living in the Amazonas region of Bolivia and explores whether Bolivian medical plants can affect the immune system and prevent or ... -
Socioeconomic aspects of lifestyle and women's health: a primary care and population perspective
(2020-03-05)Aims: To estimate growth characteristics and socioeconomic factors in relation to over-weight/obesity among 4-year-old children. To explore whether a primary care lifestyle programme reached and engaged socioeconomically ... -
Cardiovascular outcomes and extra-articular manifestations in patients with spondyloarthritis
(2020-02-27)Background: Spondyloarthritis (SpA) is a cluster of rheumatic diseases with similar clinical features, including association with extra-articular manifestations such as anterior uveitis (AU), inflammatory bowel disease ... -
Kunskapsöversikter inom arbetslivsområdet
(Samhällsmedicin och folkhälsa, Göteborgs universitet, 2020-02-17)Böcker har traditionellt varit en vanlig form av kunskapsöversikt inom de flesta vetenskapsområden. Översikter har också sedan länge publicerats i vetenskap-liga tidskrifter i de flesta vetenskapsområden. Under slutet av ... -
Outcome of Graves disease
(2020-02-05)Graves' disease (GD) is an autoimmune condition with elevated thyroid hormone levels and symptoms suggesting an affected brain. These symptoms often resolve with treatment but, for some patients, GD results in a long period ... -
Epidemiological Aspects on Assessing and Treating Dyslipidemia in Type 1 Diabetes
(2020-01-08)Background: Cardiovascular disease (CVD) is a major cause of shortened longevity in individuals with type 1 diabetes. Dyslipidemia is one of the important modifiable risk factors. Aims: To investigate different aspects ... -
Inflammatorisk tarmsjukdom (IBD) i Ronneby
(Arbets- och miljömedicin, Göteborgs universitet, 2019-12-16)I december 2013 upptäcktes höga halter av högfluorerade ämnen (så kallade PFAS) i ett vattenverk, som försörjde ⅓ av hushållen i Ronneby kommun med dricksvatten. För att undersöka om PFAS-föroreningen har lett till en ökad ... -
Sömnstörning av stomljud från tågtrafik i tunnel
(Arbets- och miljömedicin, Göteborgs universitet, 2019-10-28)Denna rapport redovisar översiktligt resultaten ifrån forskningsprojektet ”Sömnstörning av stomljud från tågtrafik”. Projektet finansierades av Trafikverket, och pågick under perioden 2016 – 2018. Under projektets gång ...