Institute of Clinical Sciences / Institutionen för kliniska vetenskaper: Recent submissions
Visas titlar 461-480 av 582
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Inflammatory responses in minor and major surgical procedures
(2010-05-12)Surgical procedures promote an inflammatory response, correlating to the extent of the procedure performed and influencing outcome after surgery. The aims of the thesis were to investigate factors modulating the inflammatory ... -
Long-term outcome of lumbar disc herniation surgery. Studies on different influencing factors
(2010-04-23)Background: A majority of patients suffering from sciatica caused by lumbar disc herniation experience a positive natural history and respond well to non-surgical treatment. Patients who fail conservative treatment and are ... -
Extracellular matrix remodelling proteases in acute appendicitis and their impact on appendiceal perforation
(2010-04-21)Abstract Background Appendicitis is associated with varying degradation of extracellular matrix involved in tissue injury. The principal aim of this study was to investigate whether immunoreactive techniques could ... -
Prostaglandins and angiogenesis in experimental cancer
(2010-04-08)Background and aim. Genes, proteins and pathways have been identified and suggested as potential targets in tumor angiogenesis, but current anti-angiogenic therapies have provided only modest benefits in survival of cancer ... -
Aspects on Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumours
(2010-03-04)Aspects on Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumours Background. Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) originate from endocrine cells of the intestinal mucosa and pancreas. The ... -
Infants with urinary tract infection - renal damage and risk factors
(2010-02-18)Background Identification of infants with urinary tract infection (UTI) who are at risk of renal scarring is an important clinical challenge with considerable economic consequences. Few issues in pediatric practice today ... -
Renal function after transplantation of the liver and intestine
(2010-01-27)Background: Chronic kidney disease (CKD) after liver (LT) or intestinal (IT) transplantation may decrease patient survival. Calcineurin inhibitors (CNI) play a major role in its development. Aims: Describe long term renal ... -
Neurochemical and neuroendocrine reactions during non-neurological surgery
(2010-01-14)Abstract Objective: To study changes in serum and cerebrospinal fluid (CSF) proteins, monoamine metabolites and hormones during non-neurological surgery. Subjects and methods: Thirty-five patients without neurological or ... -
Intestinal transplantation. Experimental and clinical studies
(2010-01-11)Intestinal preservation-reperfusion injury may result in various degrees of mucosal injury. Interestingly, the preservation injury is similar when using the current preservation solutions, which are given as a intravascular ... -
Localised and Metastatic Renal Cell Carcinoma. Aspects of Treatment.
(2010-01-11)Localised and Metastatic Renal Cell Carcinoma. Aspects of Treatment. Aims: Paper I To assess the long-term results in patients operated with NSS in situ for RCC, with special reference to their dependence on tumour grade ... -
Rejection and Immunosuppression at Uterus Transplantation: an experimental study in rodents.
(2009-12-01)Uterus transplantation is developed as a possible treatment for patients with absolute uterine factor infertility. There has been one attempt to transplant a human uterus, which however failed and more basic research is ... -
Identification of novel growth hormone-regulated factors
(2009-11-27)The studies described in this thesis aimed to identify novel factors involved in the regulation of longitudinal growth and bone mineralization in response to growth hormone (GH) treatment. This was done by performing a ... -
Mechanisms of Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia
(2009-11-26)Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects preterm infants. Increased levels of inflammatory mediators in the amniotic fluid and in the lungs of preterm infants are associated with the development ... -
Bone Mineral Density Determination in Children. Evaluation of a novel method and application to Duchenne muscular dystrophy
(2009-11-22)Aims: The overall aims of this thesis were to evaluate the dual-energy X-ray and laser (DXL) method for bone densitometry measurements of the calcaneus in children, to provide reference data for bone mineral density (BMD) ... -
Laryngopharyngeal reflux - development and refinement of diagnostic tools
(2009-11-13)Laryngopharyngeal reflux (LPR), characterized by symptoms of chronic cough, hoarseness, throat clearing, globus, laryngospasm, throat pain and excessive mucus has in recent years been recognized as an extra-esophageal ... -
Artificial blood vessels - Studies on endothelial cell and blood interactions with bacterial cellulose
(2009-11-13)Cardiovascular diseases are still the number one cause of death or invalidity in the western world today. Atherosclerotic plaques and restenosis can result in severe occlusions of peripheral and coronary arteries. Treatment ... -
Androgen-Independent Prostate Cancer - studies on angiogenesis and ADAMTS1
(2009-10-27)Androgen deprivation therapy (ADT) is the standard treatment for advanced prostate cancer since prostate tumors initially are dependent on androgens for growth. However, most tumors will eventually relapse and grow in a ... -
Cumulative Live Birth Rates after In Vitro Fertilization
(2009-10-23)Background: In vitro fertilization (IVF) has become increasingly common, today representing about 3% of all live births in some countries. Most patients have to undergo more than one treatment in order to achieve a live ... -
Arthrogryposis. Causes, Consequences and Clinical Course in Amyoplasia and Distal Arthrogryposis
(2009-10-19)Arthrogryposis Causes, Consequences and Clinical Course in Amyoplasia and Distal Arthrogryposis Background. Arthrogryposis Multiplex Congenita, AMC, is a heterogeneous condition defined as multiple congenital joint ... -
Aspects of Fluorescence diagnostics and photodynamic therapy of non-melanoma skin cancer
(2009-10-19)Aspects of fluorescence diagnostics and photodynamic therapy in non-melanoma skin cancer. Carin Sandberg Department of Dermatology and Venereology, Institute of Clinical Sciences at Sahlgrenska Academy, University of ...