Institute of Clinical Sciences / Institutionen för kliniska vetenskaper: Recent submissions
Now showing items 401-420 of 582
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Pretargeting agents and At-211-labeled effector molecules: Synthesis and preclinical evaluation for pretargeted alpha-radioimmunotherapy.
(2012-05-15)Targeted therapies are treatment regimens in which tumor specific substances incorporating some sort of cell-killing effect are administered to patients. For cancer therapy they have emerged as a means of preventing ... -
Different aspects of psoriasis etiology and treatment
(2012-05-14)Psoriasis is a chronic disease where treatments are often needed throughout life. The quality of life of patients is often affected and comorbidities are common. The overall aim of this thesis was to study treatment regimes, ... -
Long-term symptoms after breast cancer radiotherapy
(2012-04-05)Since breast cancer is the most common cancer among women worldwide and the relative 10-years overall survival is 80% there is an increasing number of women living with a history of breast cancer treatment. This results ... -
Anatomic anterior cruciate ligament reconstruction - current evidence and future directions
(2012-03-30)Injury to the anterior cruciate ligament (ACL) is one of the most common orthopedic diagnoses. It is also one of the most researched areas in orthopedic surgery, with well over eleven thousand publications. Despite this, ... -
Transmission of bone conducted sound in the human skull based on vibration and perceptual measures
(2012-03-23)For patients who are rehabilitated with bone conduction (BC) hearing aids, the position on the skull of the hearing aid is critical for the perception of the sound. The aim of this work was to describe the vibration of the ... -
Metabolic responsiveness to growth hormone in children
(2012-03-13)Metabolic effects of growth hormone (GH) therapy in short children have not been clearly established owing to the previous lack of controlled trials studying the metabolic outcome in response to different GH doses despite ... -
Towards a retained health in testicular-cancer patients - long-term cognitive function, missing a testicle and psychological needs
(2012-03-02)ABSTRACT Background: Many breast-cancer survivors experience chemotherapy-induced cognitive decline. Our knowledge about potential cognitive side-effects among testicular-cancer survivors is, however, sparse. We also lack ... -
Towards improved physical and psychological health after radiotherapy for prostate cancer - avoiding radiation - induced long-lasting gastrointestinal symptoms
(2012-03-01)There are an increasing number of irradiated prostate-cancer survivors in the world today. For many of these men survival comes at a cost: unwanted debilitating side effects due to exposure of healthy normal tissue to ... -
Aspects on local recurrence after rectal cancer surgery
(2012-02-03)Background: Local recurrence after rectal cancer surgery has a profound impact on affected patients’ lives. The overall aim of this thesis was to acquire a deeper understanding of local recurrence after rectal cancer ... -
Motion Analysis and Postural Stability of Transtibial Prosthesis Users
(2011-12-20)The AIMS of the thesis were to critically evaluate motion analysis methods used during investigations of transtibial prosthesis users, and to propose improvements to these methods. Additionally, the aim was to evaluate ... -
Optimization of radiotherapy in locally advanced lung cancer
(2011-12-20)Lung cancer is the leading cause of cancer death worldwide as well as in Sweden, where the incidence is around 3500 new cases per year. About 50% have distant metastases by the time of diagnosis and are treated with ... -
Photodynamic therapy- pain and aspects of pain relief
(2011-11-28)Photodynamic therapy – pain and aspects of pain relief Christina Halldin Department of Dermatology and Venereology, Sahlgrenska University Hospital, Institute ... -
Development of methods for evaluation and optimization of chest tomosynthesis
(2011-11-25)Tomosynthesis is a low-dose technique that has attracted increasing interest from the medical imaging community during the past decade. Tomosynthesis refers to the technique of acquiring a number of projection radiographs ... -
Ultrasonography for Diagnosis, Intervention and Follow-up in Juvenile Idiopathic Arthritis
(2011-11-25)Early therapeutic intervention and the use of novel, highly effective treatments in juvenile idiopathic arthritis (JIA) have improved the outcome in many diseased children, but have also increased the need for more precise ... -
Epidemiological Studies of Childhood Wheeze - Risk factors and Long-term Outcome
(2011-11-18)Wheezing with viral infections is common in childhood and both genetic and environmental factors have been reported to influence the risk of subsequent asthma development. The overall aim of this thesis was to study the ... -
Polycystic ovary syndrome: ovarian pathophysiology and consequences after the menopause
(2011-11-18)Polycystic ovary syndrome Ovarian pathophysiology and consequences after the menopause Johanna Schmidt Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 2011 The ... -
Cardiac surgery and the brain - studies on cerebral blood flow autoregulation and mechanisms of cerebral injury
(2011-11-09)Cardiac surgery and the brain - studies on cerebral blood flow autoregulation and mechanisms of cerebral injury Björn Reinsfelt Department of Anaesthesiology and Intensive Care, Institute of Clinical Sciences, The ... -
Apoptotic mechanisms in the neonatal brain following hypoxia-ischemia
(2011-10-28)Introduction: Neonatal encephalopathy is often perinatally acquired and caused by hypoxia-ischemia (HI). Brain injury develops with a delay, over 12-48 hours, after the insult. Hypothermia, an established neuroprotective ... -
Screening for Hypertrophic Cardiomyopathy in Asymptomatic Children and Adolescents. Psychosocial consequences and impact on quality of life and physical activity.
(2011-10-11)The aim of this thesis was to describe the consequences of being diagnosed with hypertrophic cardiomyopathy (HCM) while being asymptomatic, taking into consideration psychosocial effects and medical aspects of diagnosis ... -
Incidentally detected adrenal lesions - radiological aspects
(2011-10-10)Incidentally detected adrenal lesions (“adrenal incidentalomas”) have become a growing clinical problem due to increased and refined radiology methods. Autopsy studies show frequencies as high as 7-8% in the elderly. A ...