Institute of Clinical Sciences / Institutionen för kliniska vetenskaper: Recent submissions
Now showing items 501-520 of 582
-
Selected aspects on improving the management of skin cancer
(2009-05-13)The constant rise of skin cancer incidence rates in Sweden is a problem which requires attention. Improved techniques for prevention, early detection and effective treatment are required to face this challenging task. The ... -
Tissue remodelling proteases as prognostic factors in colon and rectal cancer
(2009-05-08)Background: Colorectal cancer is the third most common cancer in Sweden and the main treatment is surgery. The TNM classification is the principal staging tool, although insufficient in identifying all patients with poor ... -
ST analysis of the fetal ECG as an adjunct to fetal heart rate monitoring in labour-a clinical validation
(2009-05-06)The ability to make an accurate assessment of fetal well-being during labour is a great challenge. Animal and human studies have shown that fetal hypoxemia during labour can alter the shape of the fetal electrocardiogram ... -
Photdynamic therapy for treatment of Acne Vulgaris in clinical studies; dose response and mode of action
(2009-04-30)This thesis deals with the use of photodynamic therapy (PDT) for treatment of Acne Vulgaris. Acne Vulgaris is one of the most common skin disorders. Conventional treatments target the pathogenic factors and include a variety ... -
Opportunistic viral infection after paediatric transplantation
(2009-04-17)Background: Opportunistic viral infections can cause considerable morbidity and mortality in organ and stem cell transplanted (SCT) patients, mainly due to iatrogenic T cell dysfunction. Whereas in SCT patients, in general ... -
Acute achilles tendon rupture. Evaluation of treatment and complications
(2009-04-17)The overall purpose of this thesis was to evaluate the treatment of patients with an acute Achilles tendon rupture with regard to complications, function and patient-reported outcome. Moreover, the purpose was to develop ... -
Lower Urinary Tract symptoms in women - aspects on epidemiology and treatment
(2009-04-17)Lower urinary tract symptoms in women – aspects on epidemiology and treatment Lower urinary tract symptoms (LUTS) are common conditions that compromise a person’s quality of life and result in increased health care costs ... -
Congenital and Childhood Myotonic Dystrophy type 1 - the impact on central nervous system, visual and motor function
(2009-04-14)Background and aims: Myotonic dystrophy type 1 (DM1) is an autosomal dominant multisystemic disorder, caused by an expanded CTG repeat on chromosome 19. The disorder can present both in children and adults. The overall ... -
Remodelling of extracellular matrix in rectal cancer and preoperative radiotherapy
(2009-04-06)BACKGROUND Preoperative radiotherapy reduces local recurrence due to rectal cancer, but increases postoperative morbidity. The aim of this thesis was to study the impact of radiotherapy on extracellular matrix (ECM) ... -
Pulse oximetry: Evaluation of a potential tool for early detection of critical congenital heart disease
(2009-03-31)Background: About one third of newborns with life-threatening congenital heart disease leave newborn nurseries without the problem being recognized, and risk death or serious damage from circulatory collapse. The main aim ... -
Cervical and intra-amniotic markers of preterm birth and infection
(2009-03-16)Abstract Background: Preterm delivery (PTD; < 37 gestational weeks), is one of the greatest unsolved obstetrical problems worldwide. As much as 80% of the perinatal mortality and 50% of the long-term neurological handicaps ... -
Clinical and experimental studies on oxidized fragrance terpenes as contact allergens
(2009-03-02)The work presented in this thesis aims to improve the possibilities for diagnosing contact allergy to oxidized limonene and linalool and to, in patients, study contact allergy from structurally closely related hydroperoxides ... -
The acute osteoporotic vertebral compression fracture. Its natural course and characteristics.
(2009-02-21)Aim: The overall aim of this thesis was to investigate the natural course and the characteristics of the acute osteoporotic vertebral compression fracture in order to better understand and improve treatment for this type ... -
Molecular characterization of type I endometrial carcinomas
(2009-02-10)Endometrial carcinoma is the most common malignancy in the female reproductive tract. In Sweden over 1300 women are diagnosed every year, and although the prognosis is favourable in the majority of cases, about 160 ... -
Computed Tomography and Magnetic Resonance Imaging in Determination of Human Body Composition. Methodological and Applied Studies
(2009-02-06)Background: Computed tomography (CT) and magnetic resonance imaging (MRI) provide important research opportunities due to their unique capability of characterizing and quantifying tissues and organs. Ionizing radiation is ... -
Prognostic and predictive factors in colorectal cancer
(2009-02-06)Aim: The aim of the thesis was to study prognostic and predictive factors in patients treated for colorectal cancer (CRC). Method: In paper I, a retrospective comparison was made between the patients treated in 1999 ... -
Vitamin D status in psoriasis patients treated with UVB therapy
(2009-02-03)Vitamin D status in psoriasis patients treated with UVB therapy Amra Osmancevic Department of Dermatology and Venereology, Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg, Göteborg, ... -
EPILEPSY AND CHILDHOOD AUTISM - with special reference to neuropsychiatric aspects on surgical interventions for medically intractable epilepsy
(2009-01-12)Epilepsy is much more common in individuals with autism than in the general population. The extent to which epilepsy influences the outcome of autism is poorly understood. Many children with medically intractable epilepsy ... -
MUSCLE STRENGTH, GROSS MOTOR FUNCTION AND GAIT PATTERN IN CHILDREN WITH CEREBRAL PALSY
(2009-01-12)Aim The main purpose was to explore the relationship between muscle strength and walking ability in children with bilateral spastic cerebral palsy (CP), and to analyse whether muscle strength training can improve walking ... -
MUSCLE TONE IMBALANCE IN HUMAN UPPER EXTREMITY An experimental study of muscle adaptation to altered tension
(2008-11-28)Aim: The aim of this thesis was to improve outcome after tendon transfer and rotator cuff surgery by investigating the impact on response to passive mechanical testing and change in structural characteristics associated ...