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Urban Climate and Air pollution in Ouagadougou, Burkina Faso : An overview of results from five field studies
(University of Gothenburg / Göteborgs universitet, 2012)The report Urban Climate and Air pollution in Ouagadougou, Burkina Faso contains an overview of results from five field studies as well as suggestions for air pollution mitigation strategies suitable for Ouagadougou. -
Biofilms in Nitrogen Removal - Bacterial Population Dynamics and Spatial Distribution
(2012-01-12)Efficient nitrogen removal at wastewater treatment plants (WWTPs) is necessary to avoid eutrophication of recipient waters. The most commonly used approach consists of aerobic nitrification and subsequent anaerobic ... -
Symmetry of Halonium Complexes in Solution
(2012-01-13)In this thesis the symmetry of two interaction types involving electropositive halogens have been studied in solution; the N-X+-N halogen bond (X = Br or I), and the C-X+-C interaction of previously characterised, cyclic, ... -
Design and Synthesis of Chalcone and Chromone Derivatives as Novel Anticancer Agents
(2012-01-23)This thesis comprises the design and synthesis of chalcone and chromone derivatives and their use in various biological applications, particularly as anticancer agents (targeting proteins associated with cancer pathogenesis) ... -
Self-organization of nanoparticles - implications for interface biology
(2012-05-03)Cells bind to their surroundings via proteins displayed on the cell surface. These interactions support the cells and are important for many cellular processes, e.g. cell migration during morphogenesis, wound healing and ... -
Mechanistic Insights into Transition Metal Oxide Catalyzed Water Oxidation
(2012-05-14)A binuclear mechanism was proposed and evaluated by means of Density Functional Theory calculations. The central reaction steps were found to be the oxidation of the transition metal TM-OH moieties to TM=O and the subsequent ... -
Cellular Resilience and Fragility in Response to Environmental and Gene Expression Perturbations
(2012-08-30)Cells are constantly subjected to perturbations. Whether these are extracellular or intracellular, they can be detrimental to cellular fitness. The cell has evolved elaborate systems and mechanisms that allow it to remain ... -
Iron or Copper? - Method Development and Mechanistic Studies on Cross-Coupling Reactions
(2012-09-06)The area of catalysis has had an immeasurable impact on modern society. This has been acknowledged through several Nobel prizes during the 20th century ranging from Haber (1918) for the synthesis of ammonia to Richard ... -
Structural Insights at Sub-Ångstrom, Medium and Low Resolution: Crystallization of Trypsin, Bacterioferritin, Photosynthetic Reaction Center, and Photosynthetic Core Complex
(2012-09-28)The catalytic action of serine proteases depends on the interplay of a nucleophile, a general base and a general acid. The catalytic triad is composed of serine, histidine and aspartate residues. The serine acts as a ... -
Design, Synthesis, and Evaluation of Functionalized Chroman-4-one and Chromone Derivatives. Somatostatin receptor agonists and Sirt2 inhibitors
(2012-10-04)Peptides are involved in many physiological processes such as regulation of blood-pressure, food intake, pain transmission and blood-glucose levels. They consist of amino acids that are connected through amide bonds which ... -
Attenuation of acute inlammatory responses by surface nanotopography
(2012-10-04)The interaction between biology and non-viable surfaces is crucial for many organisms and cells. For example, bacterial cells need to adhere to mineral surfaces in the soil, plants climb and adhere to walls and marine ... -
Formation and Distribution of Marine Biogenic Halocarbons with Emphasis on Polar Regions
(2012-10-19)It is well-established that marine micro- and macroalgae form volatile halogenated compounds (halocarbons). Production occurs throughout the world ocean with strong regional sources in coastal areas. In the atmosphere, ... -
Selectivity of dopamine D1 and D2 receptor agonists – A combined computational approach
(2012-10-26)Dopamine (DA) is an endogenous neurotransmitter acting in the central nervous system. DA plays a key role in many vital brain functions such as behavior, cognition, motor activity, learning, and reward. Dopamine receptors ... -
Static and Dynamic Measurements of Neurotransmitters in Drosophila Brain
(2012-11-15)Neurotransmitters, the substances neurons use for communication, and their precursors and metabolites are of obvious importance for the wellbeing of the individual and when the neurotransmitter balance is off it can lead ... -
Synthesis, Pharmacological Characterization and QSAR Modelling of 4-Phenylpiperidines and 4-Phenylpiperazines Effects on the dopaminergic neurotransmission in vivo
(2012-11-19)The endogenous neurotransmitter dopamine (DA) is involved in several functions that are controlled from the central nervous system (CNS), for example behaviour, memory, cognition and reward. A disturbed dopaminergic ... -
The Synthesis and Use of Certain Pyridine Derivatives as Modulators of the G-protein Coupled Receptors mGlu5 and P2Y12
(2012-11-20)The glutamatergic mGlu5 receptor and the purinergic P2Y12 receptor are two important targets in the development of novel treatments of gastroesophageal reflux disease (GERD) and thrombosis, respectively. Synthesis was ... -
Algorithms and Interaction Potentials: phase density, surface tension and carbon dioxide
(2012-12-14)This thesis is an amalgamation of articles (Papers I–V) by the author. We present a perturbation algorithm to calculate the phase density, and thus the partition function including its temperature dependence. It works ... -
The Linnaeus-Palme Exchange program
(University of Gothenburg / Göteborgs Universitet, 2013)The report is an evaluation of five years of Linnaeus-Palme exchange programme between the chemistry departments at University of Gothenburg, Sweden and University of the West Indies, Jamaica. The exchange programme gives ... -
Regulation and transport mechanisms of eukaryotic aquaporins
(2013-01-11)Aquaporins are found in all kingdoms of life where they are involved in water homeostasis. They are small transmembrane water conducting channels that belong to the ancient protein family Major Intrinsic Proteins (MIP). ... -
Formation, ageing and thermal properties of secondary organic aerosol
(2013-02-07)In order to properly represent and predict the effects of aerosol in climate systems, an accurate description of their formation and properties is needed. This thesis describes work done to increase the knowledge of processes ...