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A Holistic View on Aquaporins: Production, Structure, Function and Interactions
(2020-10-21)Aquaporins are specialised membrane proteins, which regulate the water homeostasis of cells. In eukaryotic organisms, this process is tightly regulated, and aberrations in aquaporin functionality lead to severe pathologies ... -
A Soot Transformation Study: Interactions Between Soot, Sulfuric Acid and Secondary Organic Aerosol (SOA)
(2018-01-19)Atmospheric black carbon (BC), generally called soot, is the most important aerosol component that warms the Earth’s climate significantly, and reducing atmospheric soot level has been proposed as a strategy for near-term ... -
A Waterborne Colloidal Model System Consisting of Fluorinated Spheres Bearing Grafted PEG: Synthesis, Characterization and Properties
(2016-01-08)Model systems have expanded our knowledge of numerous phenomena in Colloid Science, such as the appearance of glasses, order-disorder transitions involving crystals and attraction induced formation of gels. So far, the ... -
Adaptation and Protein Quality Control Under Metalloid Stress
(2015-04-22)Toxic metals and metalloids are emerging as major environmental pollutants, having ecological consequences as well as being linked to a broad range of degenerative conditions in animals, plants and humans. While the toxicity ... -
Advances in Membrane Protein Structural Biology: Lipidic Sponge Phase Crystallization, Time-Resolved Laue Diffraction and Serial Femtosecond Crystallography
(2013-05-08)Membrane proteins carry out many essential tasks in cells such as signaling and transport, or function as electron carriers in photosynthesis and cellular respiration. The aim of this thesis has been to develop new and ... -
Airborne particulate matter in a Sub-Saharan Africa city: Nairobi, Kenya, and at an Equatorial high altitude site: Mount Kenya
(2017-09-13)In Sub-Saharan Africa (SSA), air quality is gravely understudied despite the existing influential factors such a rapid urbanization and population growth that negatively affect the environment. Majority of urban areas in ... -
Algorithms and Interaction Potentials: phase density, surface tension and carbon dioxide
(2012-12-14)This thesis is an amalgamation of articles (Papers I–V) by the author. We present a perturbation algorithm to calculate the phase density, and thus the partition function including its temperature dependence. It works ... -
Alkali Metals and Tar in Biomass Thermochemical Conversion: Development and Application of Online Measurement Techniques
(2018-02-08)Biomass is a renewable resource that can substitute the fossil-based products we depend on today. However, the conversion techniques require further improvement in order to be competitive with the traditional industry. One ... -
Alkali Release and Effects on Biomass Thermal Conversion Processes
(2022-09-19)High alkali content is an important feature of biomass, and it has a series of implications for thermal conversion processes. This thesis focuses on the release of alkali during various biomass thermal conversion processes, ... -
Allergenic Oxidation Products from Fragrance Terpenes. Chemical Analysis and Determination of Sensitizing Potency
(2013-09-05)The ubiquitous presence of fragrance compounds in consumer products has resulted in a high frequency of contact allergy to fragrances in the population. For prevention purposes and according to EU regulations, cosmetics ... -
Anti-Virulence Strategy Targeting Sortase A, A Structural Investigation of the Sortase A Enzyme, and the Identification, Synthesis, and Evaluation of Sortase A Inhibitors
(2019-09-20)The emergence of multi-resistant bacteria and their continuous spread is one of the greatest challenges when treating bacterial infections. Increased understanding of bacterial pathogenesis has revealed new strategies for ... -
Antibiotic sensitivity and horizontal gene transfer in Escherichia coli - A genome-wide perspective
(2022-11-01)Since their discovery in the early 20th century, antibiotics have truly revolutionized human medicine. They have allowed us to treat diseases that were previously untreatable and have become a staple of modern medicine. ... -
Arsenic-induced protein aggregation and toxicity in Saccharomyces cerevisiae
(2022-08-29)Arsenic is prevalent in the environment and this toxic metalloid poses a substantial threat to human health with 100-200 million people worldwide estimated to be at risk. Chronic exposure to arsenic is associated with ... -
Atmospheric Chemistry of Volatile Organic Compounds: Oxidation Products, Mechanisms and Secondary Organic Aerosol Formation
(2019-01-15)The results from this work are a piece in understanding the complex puzzle of atmospheric aerosol formation. Secondary organic aerosol (SOA) formed by the oxidation of volatile organic compounds (VOC) in the atmosphere ... -
Atmospheric oxidation: Formation and aging of biogenic and traffic-related secondary aerosols
(2018-01-11)Atmospheric aerosol particles affect the quality of life by influencing climate and by being a significant component of air pollution. Once a particle is released into or formed in the atmosphere, several processes begin ... -
Attenuation of acute inlammatory responses by surface nanotopography
(2012-10-04)The interaction between biology and non-viable surfaces is crucial for many organisms and cells. For example, bacterial cells need to adhere to mineral surfaces in the soil, plants climb and adhere to walls and marine ... -
Biofilms in Nitrogen Removal - Bacterial Population Dynamics and Spatial Distribution
(2012-01-12)Efficient nitrogen removal at wastewater treatment plants (WWTPs) is necessary to avoid eutrophication of recipient waters. The most commonly used approach consists of aerobic nitrification and subsequent anaerobic ... -
Biogenic Halocarbons in Polar Sea Ice
(2014-04-28)Sea ice is to date a rather poorly investigated part of the cycling of volatile halogenated organic compounds, halocarbons. These compounds are natural sources of reactive iodine and bromine to the atmosphere, and are ... -
Biophotonics Targeting Pharmaceutical Challenges
(2018-08-23)The study of the interaction between light and biological matter, called biophotonics, contributes to our understanding of biological systems - from subcellular compartments up to the human organ system. Herein, light is ... -
Breaking the symmetry: creation and transfer of optical activity via total spontaneous resolution and stereoselective reactions
(2013-03-28)The generation of optical activity from achiral or racemic precursors – absolute asymmetric synthesis – is discussed in relation to the origin of biomolecular homochirality but is also often (incorrectly) regarded as ...