Doctoral Theses from Sahlgrenska Academy: Recent submissions
Now showing items 181-200 of 2013
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On parental self-efficacy in families with paediatric cataract and its clinical implications
(2020-11-02)Introduction: Parent participation is implicit in all paediatric care. Responsibility for the treatment after cataract surgery (contact lenses, patching, eye drops and being alert to signs of complications) mainly lies ... -
Exploring novel therapeutic strategies in neuroblastoma
(2020-10-29)Neuroblastoma (NB) is the most frequently diagnosed extracranial tumour in children, which arises from transient embryonal tissue of the neural crest that fails to complete terminal differentiation into neurons. Even after ... -
Cam morphology of femoroacetabular impingement syndrome in athletes - Clinical and radiological studies
(2020-10-28)Femoroacetabular impingement syndrome (FAIS) leads to hip pain and reduced hip function in young athletes. Recent studies have reported high-impact sporting activities during adolescent growth as an important cause of cam ... -
Postural balance, anxiety and motor function after stroke, at a very early supported discharge with continued rehabilitation
(2020-10-23)The overall aim of this thesis was to investigate postural balance, anxiety and motor function the first year after stroke and whether postural balance, anxiety and motor function was different at the intervention of Very ... -
Transurethral resection of the prostate: studies on efficacy, morbidity and costs
(2020-10-23)Lower urinary tract symptoms (LUTS), based on benign prostatic enlargement (BPE), are increasingly common, in ageing men. A considerable amount of men will ultimately progress with deteriorating symptoms or with the ... -
Revealing the complex nature of amyloid beta and its relation to dementia
(2020-10-20)Alzheimer disease (AD) is the most common type of dementia and characterized by the accumulation of amyloid plaques in the extracellular space of the brain parenchyma. Amyloid plaques consist of amyloid beta peptides (Aβ). ... -
New perspectives on imaging of urinary tract infections in infants
(2020-10-20)Background: Urinary tract infection (UTI) is a common disease in infants that may lead to renal damage with an increased risk of long term complications. The diagnostic imaging aims to identify risk factors as underlying ... -
Serotonin in Fear and Anxiety
(2020-10-16)That the neurotransmitter serotonin (5-HT) has a central role in fear and anxiety is supported by numerous experimental and clinical studies. Arguably the most illustrative example is the effect of serotonergic-acting ... -
The epidemiology of cardiac arrest - In-hospital risk assessment, treatment and outcome
(2020-10-12)AIM: To describe and analyse sudden cardiac arrest, both in hospital and out of hospital, from an epidemiological perspective, by early prediction, by comparing changes over time in relation to aetiology, characteristics, ... -
Physical activity on prescription in primary care. Impact on physical activity level, metabolic health and health-related quality of life, and its cost-effectiveness - a short- and long-term perspective
(2020-10-08)Non-communicable diseases (NCDs) are the leading cause of death globally and one of the major health challenges of the 21st century. In Sweden, NCDs are estimated to account for 90 % of all deaths. Strong evidence indicates ... -
Chromatin and transcriptome-based integrative approaches to profile functional long noncoding RNAs - A computational approach
(2020-10-07)One of the major hallmarks of cancer is aberrant or uncontrollable cell division, which occurs due to a defective cell cycle process. During the synthesis phase (S-phase) of the cell cycle, before cell division or mitosis ... -
Dynamic ultrasound investigation of clubfeet, 0 - 4 years of age, with normal controls
(2020-10-07)Clubfoot is one of the most common congenital deformities, 1-6/1,000 births in Europe and up to 5-6/1,000 in Polynesia. The Ponseti method is now widely regarded as the method of choice for treatment. The treatment starts ... -
Neurochemical and cognitive aftermaths of surgery - studies on short- and long-term effects of surgery and anesthesia
(2020-10-01)Background: Each year, around the world, more than 230 million patients have surgery. Improvements in healthcare have resulted in older and sicker patients undergoing surgical interventions. As a result, surgical safety ... -
Studies on the Etiology of Parkinson's disease
(2020-10-01)ABSTRACT Parkinson’s disease (PD) is the second most common neurodegenerative disorder in the world and affects around 1% of the population over 60 years of age. The main symptoms of PD include bradykinesia, resting ... -
Acute respiratory infections among children in the Democratic Republic of Congo - nasopharyngeal pathogens, antibiotic resistance and vaccination
(2020-09-29)ABSTRACT Acute Lower Respiratory Infections (ALRI) remain a leading cause of morbidity and mortality among children in the Democratic Republic of the Congo (DR Congo). The pneumococcal conjugate vaccine PCV13 was ... -
Diagnosis and management of periprosthetic joint infections
(2020-09-18)Periprosthetic joint infection (PJI) is a severe complication to hip and knee arthroplasty surgery. In the light of its devastating implications for the affected patient, its great economic impact on the health care system ... -
Aspects of teamwork and intraoperative factors in the operating room
(2020-09-07)The work in high-risk environments like an operating room is complex. The operating team consist of many professions with different tasks cooperating towards a common goal, the performance of safe surgery. The operating ... -
Lipoproteins in Staphylococcus aureus infections
(2020-09-04)Staphylococcus aureus (S. aureus) infections remain a major challenge for the healthcare system, and new treatment options are highly demanded. S. aureus is a pathogenic microorganism, responsible for a broad range of ... -
Aplastic anemia - a population-based study of epidemiology, treatment, and prognostic factors
(2020-09-03)Background and aims. Aplastic anemia (AA) is a rare but life-threatening disease. The introduction of immunosuppressive treatment (IST) and hematopoietic stem cell transplantation (HSCT) has considerably improved the outcome ... -
Occupational engagement after stroke - a long-term perspective
(2020-09-03)Introduction: In the literature it is recognized that stroke can have lifelong consequences and that these consequences become evident in the occupations that constitute everyday life. With an increase in prevalence and ...