Doctoral Theses from Sahlgrenska Academy: Recent submissions
Now showing items 481-500 of 2013
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Exercise-based cardiac rehabilitation, physical fitness, and physical activity in cardiac disease
(2018-09-12)Background: Evidence suggests that individualised exercise-based cardiac rehabilitation should be offered to patients with ischemic heart disease and chronic heart failure (HF) because it improves physical fitness and ... -
Learning for life - How children with unilateral spastic cerebral palsy learn to master bimanual activities
(2018-09-03)Background: For children with unilateral spastic cerebral palsy (USCP), activities in daily life pose a challenge due to reduced function in one hand. Aim: To study the development of hand function and occupational ... -
Delayed labour - risk factors, use of oxytocin and outcomes
(2018-08-31)Background and aim: Delayed labour refers to progress that is slower than what is considered normal and the most common cause of delayed progress is inadequate uterine contractions. It primarily affects nulliparous women ... -
Chemokine responses and T cell recruitment in central nervous system alphaherpesvirus infections
(2018-08-29)This thesis is focused on members of the alphaherpesvirus family; the two herpes simplex viruses and varicella zoster virus. Herpes simplex virus type 1 mainly causes cold sores and type 2 gives rise to genital blisters. ... -
Intravoxel incoherent motion modeling - Optimization of acquisition, analysis and tumor tissue characterization
(2018-09-13)Intravoxel incoherent motion (IVIM) analysis provides a means to obtain information on diffusion and perfusion from a single MRI sequence. The measurements are completely noninvasive and the results have been shown to be ... -
Genetic Studies of Familial Vesicoureteral Reflux
(2018-08-31)Vesicoureteral reflux (VUR) is a common congenital anomaly with a high risk of recurrent urinary tract infections (UTI) and, as a consequence, scarring of the renal parenchyma. Additionally, high-grade reflux is often ... -
Potential Therapeutic Applications of Novel Bioengineered Tissues and Organs Using Methods of Decellularization and Recellularization
(2018-09-04)The transplantation of personalized organs or tissues will benefit patients with various diseases and disorders. Decellularization is a method to generate an acellular, non-immunogenic natural scaffold. The personalized ... -
STK25 as a regulator of lipid accumulation
(2018-08-24)Type 2 diabetes mellitus (T2DM) and nonalcoholic steatohepatitis (NASH), a progressive form of nonalcoholic fatty liver disease (NAFLD), have become widespread metabolic disorders that have reached epidemic proportions. ... -
Priority setting in health care and public health. The role of health economics
(2018-08-23)The aim of this thesis is to analyze the role of health economics for priority setting in health care and public health. Four papers provide the basis for the analysis. Paper I contains an application of a typical ... -
On the Effects of Sensory Noise in ADHD
(2018-08-31)Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders amongst children of the developed world. The main symptoms of the disorder include hyperactivity, inattention and ... -
Bringing MEG towards clinical applications
(2018-08-21)Magnetoencephalography (MEG) is a passive, non-invasive functional neuroimaging technique for recording magnetic fields generated by neuronal currents in the brain. MEG provides a unique capability to map the electrophysiology ... -
Epidemiology, molecular characterization of hepatitis viruses in Rwanda and implication on liver disease
(2018-08-20)Hepatitis viruses cause major health problems worldwide and, according to WHO, is the seventh leading cause of death globally. It is primarily hepatitis B and C virus that causes chronic hepatitis, liver damage and fibrosis, ... -
On Characteristics of Burning Mouth Syndrome Patients
(2018-08-20)Burning Mouth Syndrome (BMS) is a condition with unknown aetiology that is characterised by a chronic unremitting burning sensation in the oral mucosa. This condition, which affects mainly middle-aged and older women, ... -
Cardiovascular health promotion among Nepalese mothers with young children: Need assessment, development, implementation, and impact of the HARDIC trial
(2018-06-07)Background Nutritional transition toward a high-fat and high-energy diet, decreasing physical activity level, and poor knowledge about cardiovascular health contribute to a rising burden of cardiovascular disease in ... -
Genetic studies of the regulation of bone parameters and serum testosterone
(2018-05-29)Osteoporosis is a common disease characterized by low bone mass and microarchitectural deterioration of bone tissue leading to increased risk of fracture and represents a huge economic burden on health care systems. The ... -
Effect of acid and alkali formation on pH in the dental biofilm with reference to caries
(2018-05-28)Dental caries is a common multifactorial disease where a frequently low pH in the dental biofilm (dental plaque) plays an important role for caries occurrence and progress. The plaque-pH is lowered by acid formation from ... -
Understanding the regulatory requirements for gut IgA B cell responses and their potential role in mucosal vaccine development
(2018-05-28)It is important to understand gut B cell differentiation, from the activation of cells at inductive lymphoid sites to the formation of gut plasma and memory B cell, to be able to develop efficient oral vaccines but the ... -
Evaluating benefits and harms of screening - the streetlight effect?
(2018-05-25)The general aim of this thesis was to explore how the benefits and harms of screening for a potentially life-threatening disease can be evaluated. Papers I and II are a Cochrane Systematic Review on screening for malignant ... -
Nutritional aspects of advanced Head and Neck Cancer and impact of different factors in Head and Neck Cancer of Unknown Primary
(2018-05-25)Background/Aims: Swallowing problems and malnutrition are common in advanced head and neck (HN) cancer. The aim of paper I was to study whether percutaneous endoscopic gastrostomy (PEG) affected the long-term swallowing ... -
Hearing-related symptoms among women - Occurrence and risk in relation to occupational noise and stressful working conditions
(2018-05-24)A considerable amount of research has been devoted to the risk of noise-induced hearing loss among industry workers – the majority of whom are men. Much less research has been done in female-dominated human service ...