| dc.contributor.author | Gatzwiller, Linnea | |
| dc.contributor.author | Vänman, Emmy | |
| dc.date.accessioned | 2022-06-21T14:45:35Z | |
| dc.date.available | 2022-06-21T14:45:35Z | |
| dc.date.issued | 2022-06-21 | |
| dc.identifier.uri | https://hdl.handle.net/2077/72272 | |
| dc.description | Effect of carbohydrate counting on HbA1c in children and
adolescents with diabetes type 1 - A systematic review.
Abstract:
Aim: Through this systematic review examine the evidence for the effect of
carbohydrate counting on HbA1c in children and adolescents with type 1
diabetes.
Search
strategy:
The literature search was conducted during 19-20 March 2022 in the
databases Scopus and PubMed. Keywords used were HbA1c, diabetes
type 1, RCT, children, youth, carbohydrate counting. Synonyms to these
terms were also used.
Selection
criteria:
Inclusion criteria were human, randomized controlled trials performed
for at least one year on children and adolescents under 18 years with type
1 diabetes. The intervention was carbohydrate counting with an
associated education and a control group with standard diet and diabetes
treatment. The efficacy measure for the included studies was change in
HbA1c reported as either percent or in mmol/mol. The exclusion criteria
were studies where HbA1c was reported as a mean over the study period.
Studies done in patients with type 2 diabetes were also excluded.
Data collection
and analysis:
Studies that were not excluded due to title and/or abstract were reviewed
in full text. The articles that met the inclusion criteria were quality
reviewed separately based on the Swedish Agency for Medical and
Social Evaluation, SBU's template for randomized controlled trials,
where risk of bias was evaluated. An overall assessment of the strength
of evidence was also determined according to the Grading of
Recommendations Assessment Development and Evaluation, GRADE
for HbA1c at three and twelve months, respectively.
Main results: Two studies were included with a total of 127 participants, where the risk
of bias was assessed as moderate and high, respectively. The first study
showed that carbohydrate counting has a marginal positive effect after
three months. After twelve months, no significant positive effect was
shown in any of the included studies.
Conclusion: There is low scientific evidence (++) that carbohydrate counting lowers
HbA1c in children and adolescents with type 1 diabetes. | en_US |
| dc.description.abstract | Syfte: Att med denna systematiska litteraturöversikt undersöka evidensen för
effekten av kolhydraträkning på HbA1c hos barn och ungdomar med
diabetes typ 1.
Sökväg: Litteratursökning utfördes 19-20 mars 2022 i Scopus och PubMed.
Sökord som användes var HbA1c, diabetes type 1, RCT, children, youth,
carbohydrate counting samt synonymer.
Urvalskriterier: Inklusionskriterierna var humana RCT utförda under minst ett år på barn
och ungdomar under 18 år med diabetes typ 1. Interventionen skulle vara
kolhydraträkning med tillhörande utbildning och en kontrollgrupp med
konventionell kostbehandling vid diabetes samt diabetesbehandling.
Effektmåttet för de inkluderade studierna var en förändring i HbA1c
redovisat i procent eller mmol/mol. Exklusionskriterierna var studier där
HbA1c redovisats som medelvärde över studieperioden och studier där
diabetes typ 2 förekom.
Datainsamling
och analys:
De studier som inte exkluderats på grund av titel och/eller abstrakt
granskades i fulltext. De artiklar som uppfyllde inklusionskriterierna
kvalitetsgranskades med Statens beredning för medicinsk och social
utvärdering, SBU:s mall Bedömning av randomiserade studier där risk
för systematisk snedvridning utvärderades. Därefter utfördes en
evidensgranskning och bedömning utefter Grading of Recommendations
Assessment Development and Evaluation, GRADE för HbA1c vid tre
respektive tolv månader.
Resultat: Två studier inkluderades med 127 deltagare. De bedömdes ha måttlig
respektive hög risk för bias. Ena studien visade att kolhydraträkning ger
en marginell positiv effekt efter tre månader. Efter tolv månader visades
ingen signifikant positiv effekt, i någon av studierna.
Slutsats: Det vetenskapliga underlaget (++) för att kolhydraträkning sänker
HbA1c hos barn och ungdomar med diabetes typ 1. | en_US |
| dc.language.iso | swe | en_US |
| dc.subject | HbA1c | en_US |
| dc.subject | Kolhydraträkning | en_US |
| dc.subject | Diabetes typ 1 | en_US |
| dc.subject | Barn | en_US |
| dc.subject | Unga | en_US |
| dc.subject | Carbohydrate Counting | en_US |
| dc.subject | Diabetes type 1 | en_US |
| dc.subject | Children | en_US |
| dc.subject | Youth | en_US |
| dc.title | Kolhydraträkning och dess effekt på HbA1c hos barn och ungdomar med diabetes typ 1 | en_US |
| dc.title.alternative | En systematisk översiktsartikel | en_US |
| dc.type | Text | |
| dc.setspec.uppsok | Medicine | |
| dc.type.uppsok | M2 | |
| dc.contributor.department | Göteborgs universitet/Institutionen för medicin | swe |
| dc.contributor.department | University of Gothenburg /Institute of Medicine | eng |
| dc.type.degree | Student essay | |
