Sahlgrenska Academy / Sahlgrenska akademin: Recent submissions
Now showing items 761-780 of 2677
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Fitness, cognition and cardiovascular disease. Epidemiological studies.
(2017-11-23)Abstract Physical activity and fitness have well established health bringing benefits. Low soci-oeconomic status is a known risk factor for cardiovascular disease. This association is commonly attributed to individual ... -
Clinical and Molecular Studies on Impacted Canines and the Regulatory Functions and Differentiation Potential of the Dental Follicle
(2017-11-20)Background: Impaction of the permanent maxillary canines, which is a common problem in dentistry, may require surgery and long-term orthodontic treatment. Until now, impaction has mostly been linked to physical obstructions ... -
Language ability in patients with low-grade glioma - detecting signs of subtle dysfunction
(2017-11-17)Background: Low-grade glioma (LGG) is a slow-growing brain tumour often situated in or near areas involved in language and/or cognitive functions. Consequently, there is a risk that patients develop language impairments ... -
Community onset sepsis in Sweden - a population based study
(2017-11-17)Sepsis and previously “severe sepsis” are concepts used for denoting organ dysfunction caused by acute infection. Organ dysfunction correlates to increased case fatality rates. Sepsis is a common cause of hospitalization. ... -
Achilles tendon rupture: the evaluation and outcome of percutaneous and minimally invasive repair
(2017-11-17)Acute Achilles tendon rupture is common and has increasing incidence. This is thought to be due to increasing activity and sports participation in middle age. Sustaining an Achilles tendon rupture means a long rehabilitation ... -
Acute Achilles tendon rupture - The impact of calf muscle performance on function and recovery
(2017-11-17)There is an ongoing debate about the optimal treatment for patients with an acute Achilles tendon rupture. The overall purpose of this thesis was to acquire a greater knowledge of the way patients recover at different time ... -
Characterizing the role of long non coding RNAs epigenetic regulators in disease model
(2017-11-17)Long non-coding RNAs (lncRNAs) are a class of biological molecules which are transcribed from DNA but are not translated into any protein. LncRNAs have been identified as critical players in gene regulation. Misregulation ... -
Gait and motion analysis of hip arthroplasty. Validity, reliability and longterm results
(2017-11-17)Introduction: Walking is one of the most fundamental activities of daily living in humans, when the hip joints transfer power between the lower extremities and the pelvis. Hip osteoarthritis (OA) will more or less influence ... -
Benefits and risks with digital dermoscopy and teledermoscopy
(2017-11-16)The increasing incidence of malignant melanoma and non-melanoma skin cancer (NMSC) makes it necessary to optimize the management of patients with suspicious skin lesions, from triaging, to establishing a diagnosis and ... -
Aspects on the functional characteristics of the Roux-limb after Gastric Bypass surgery
(2017-11-10)Background: Bariatric surgery, and particularly the Roux-en-Y Gastric Bypass (RYGBP) procedure, has highlighted the central role of the gastrointestinal tract in the regulation of body weight and metabolism. The Roux-limb ... -
Systematiska kunskapsöversikter; 10. Occupational Heat Exposure
(Arbets- och miljömedicin, Göteborgs universitet, 2017-11-11)The present review covers a wide scope of occupational heat stress relatedissues. The problematics related to climate change have placed heat exposure on the agenda. As a result, the research on heat effects has increased ... -
On nerve function after Orthognatic Surgery
(2017-11-09)Background Orthognathic surgery is a surgical intervention to correct dentofacial anomalies. It is a complicated treatment that involves cooperation of different specialties. The success of orthognathic surgery is ... -
Impact of NK cell repertoires on immunotherapy in acute myelod leukemia
(2017-11-08)Natural killer (NK) cells are lymphocytes endowed with cytotoxicity against aberrant cells, including transformed and virus-infected cells. NK cell function is dictated by a fine-tuned interplay between activating and ... -
The IL-23 axis and innate immunity in the airways
(2017-11-08)The Interleukin-23 (IL-23) axis is a communication system that integrates innate and adaptive immunity. When triggered by microbial stimuli, antigen presenting cells can secrete the cytokine IL-23, leading to the production ... -
Genomic instability and genetic heterogeneity in neuroblastoma tumours
(2017-11-03)Javanmardi, N., 2017, Genomic instability and genetic heterogeneity in neuroblastoma Department of Pathology and Clinical Genetics, Institute of Biomedicine at Sahlgrenska Academy, University of Gothenburg, Sweden Neuroblastoma ... -
STK25- a new key regulator of metabolic profile and a possible target for anti-diabetic drug
(2017-11-02)Type 2 diabetes (T2D) affects at least 285 million people worldwide and its prevalence is rapidly increasing. Understanding the molecular mechanisms controlling ectopic lipid deposition and insulin response in metabolic ... -
Fibrinogen, platelet and factor XIII supplementation in cardiac surgery: In vitro and in vivo studies
(2017-11-02)Background: There is a high risk of bleeding complications in cardiac surgery. Fibrinogen and platelet concentrates are often used to treat perioperative bleeding, but there is little information about its efficacy. The ... -
Infections associated with percutaneous osseointegrated titanium implants for limb prostheses
(2017-10-26)Femoral amputation is a devastating event. Percutaneous, bone anchored prosthetic systems reduce problems associated with socket suspended prostheses, but the design is inherently vulnerable to infection. The aims of this ... -
Epigenetic regulation of oncogenes and tumor suppressors in chronic lymphocytic leukemia
(2017-10-26)DNA methylation is one of the well-known epigenetic modifications. Aberrant DNA methylation has been shown to have a major role in tumorigenesis and is associated with tumor aggressiveness and inferior outcome in various ...