Sahlgrenska Academy / Sahlgrenska akademin: Recent submissions
Now showing items 781-800 of 2677
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Stem cells in the adult heart - 3D culture, isolation of side population cells and search for a stem cell niche
(2017-10-26)Cardiac tissue shows a poor regenerative capacity. From 2003 reports, mostly based on animal models, have showed existence of stem cells also in the heart. Using 14C measurements, a slow but steady turnover of the cardiac ... -
Trochanteric Hip Fractures Clinical Outcomes and the Cut-out Complication
(2017-10-24)The established treatment for trochanteric hip fractures is internal fixation, either intramedullary (nail) or extramedullary (plate). Approximately 10% of these patients suffer from mechanical complications, the most ... -
Femoroacetabular Impingement: The Pursuit of Evidence
(2017-10-20)Femoroacetabular Impingement (FAI) is an important cause of hip pain in the young adult. It is the result of abnormal contact between the femoral head and neck junction and the acetabular rim. Although FAI has only recently ... -
Exploring the heterogeneity of the hematopoietic stem and progenitor cell pool in cord blood
(2017-10-17)Hematopoietic stem cell transplantation (HSCT) is a curative treatment for a wide range of malignant and hereditary disorders. It is yet the only clinically established stem cell treatment. Hematopoietic stem and progenitor ... -
Modulation of Receptor Signaling and Functional Selectivity in Neutrophils
(2017-10-17)Neutrophils are important effector cells of the innate immune system and in the regulation of inflammation. Many of their functions, such as chemotactic migration, secretion of granule constituents and activation of the ... -
Symptomatic Carotid Stenosis - optimal timing of surgical treatment
(2017-10-17)Abstract In patients with symptomatic carotid artery stenosis is convincing evidence that carotid endarterectomy (CEA) confers maximum benefit if performed within 14 days from index event. Patients with TIA or minor stroke ... -
Sweet Taste Perception in Relation to Oral and General Health
(2017-10-17)The aims of this thesis were to study the difference in sweet taste perception, dental caries and BMI between three different geographical areas (Italy, Mexico and Saudi Arabia) and to elucidate the relationship of sweet ... -
Dental acrylates and methacrylates - Interactions with the immune system
(2017-10-10)Professionals working in dentistry have reported adverse effects, such as allergic contact dermatitis due to exposure to different methacrylates/acrylates. Leakage of such monomers from dental fillings due to incomplete curing ... -
Offenders of intimate partner violence: Aggressive antisocial behavior and mental health
(2017-10-05)Background: Studies on the impact of mental disorders on aggressive antisocial behaviors constitutes an extensive body of literature. What patterns of mental disorders that contribute the most to the development of such ... -
Piperaquine and Metabolites - Bioanalysis and Pharmacokinetics
(2017-09-28)Antimalarial piperaquine (PQ) is currently used as a partner drug with dihydroartemisinin (DHA), exhibiting high cure rates (>95%) for P. falciparum. Despite its raising usage worldwide with DHA, PQ is synthetically developed ... -
Diets of European children, with focus on BMI, well-being, and families The IDEFICS/I.Family cohort
(2017-09-28)The overall aim of this thesis was to investigate children’s diet, BMI z-score, and parental feeding practices (PFPs), in relation to mutans streptococci (MS) count, psychosocial well-being and children’s BMI trajectory, ... -
Importance of bacterial hydrogen sulfide in the pathogenesis of periodontal diseases
(2017-09-27)Hydrogen sulfide (H2S) is one of many end-products of the proteolytic activities in the subgingival microbiota in patients with periodontal diseases, such as gingivitis and periodontitis. Although H2S is generally regarded ... -
Three-dimensional guidance for Endovascular Aortic Repair
(2017-09-25)Image fusion (IF) of preoperative computed tomography (CT) with intraoperative cone-beam CT (CBCT) is a potentially powerful tool for guidance during endovascular aortic repair (EVAR). It may improve intraoperative anatomic ... -
The impact of railway vibration and noise on sleep
(2017-09-25)Sleep is a vital component of good health, and sleep loss is associated with impaired cognition, decreased psychomotor performance, cardiovascular disease, adverse effects on endocrine and metabolic function, negative mood, ... -
Prevalence and treatment of patients with heart failure with special emphasis on diuretics
(2017-09-21)Background: Heart failure (HF) is a major health problem worldwide with an estimated prevalence of about 1-2% in the Western world. The temporal trend for prevalence of HF has never been investigated in a nationwide ... -
Painting from Within - Developing and Evaluating a Manual-based Art therapy for Patients with Depression
(2017-09-13)Aim: The overall aim was to develop and evaluate a manual-based art-therapy programme for patients with depression, and hence, to clarify treatment effects and to describe participants’ experiences of the treatment. The ... -
Improvements in hip arthroplasty - did they work? Evaluations of different articulations and fixation concepts.
(2017-09-07)Today, total hip arthroplasty (THA) is one of the safest and most efficient surgical treatments. New materials, surgical techniques and design concepts intended to improve THA have not always been successful. Thorough ... -
Natural killer T (NKT) lymphocytes regulate of intestinal tumor immunity
(2017-09-01)CD1d-restricted natural killer T (NKT) lymphocytes are known as potent early regulatory cells of immune responses, acting as a bridge between innate and adaptive immunity. While invariant NKT (iNKT) cells have a protective ... -
Osteocytes as indicators of bone quality - multiscale structure-composition characterisation of the bone-implant interface
(2017-09-01)By virtue of certain design features, bone anchored metal implants can be made to elicit a strong initial osteogenic response, i.e., the amount of bone formed. While quantitative differences are often lost at longer follow ... -
Endovascular treatment of acute ischemic stroke
(2017-09-01)Background: Intravenous thrombolysis is effective in patients with minor stroke but not in patients with moderate or major stroke due to large vessel occlusion. Endovascular stroke treatment offers a high recanalization ...