Sahlgrenska Academy / Sahlgrenska akademin: Recent submissions
Visas titlar 201-220 av 2677
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Vaccine-induced aluminium allergy and long-lasting subcutaneous itching nodules
(2021-11-09)Background: Aluminium contact dermatitis is rare even though aluminium is frequently used in antiperspirants and sunscreens. Sensitisation to aluminium is mostly a side effect of aluminium-adsorbed vaccines. These can ... -
The population burden of gout and urate in Western Sweden
(2021-11-02)Background: Gout is the most common type of inflammatory arthritis and is associated with several comorbidities and an increased risk of cardiovascular disease (CVD). However, data on the epidemiology and comorbidity ... -
Spinal column and hip joint changes, and their correlation to back pain in young athletes - Radiological and Clinical Studies
(2021-10-29)Background: Young athletes are at increasing risk for spinal column injuries and back pain due to excessive sporting activities, with potential development of complications ... -
Signaling pathways and novel genetic factors involved in modulation of cisplatin response in C. elegans
(2021-10-29)Cancer is a major cause of mortality throughout the world. Despite the effort of the scientific community, plenty remains to understand about the biology or genetics of cancer. In solid tumors often as many as 90-99% of ... -
Towards a balanced radiotherapy workflow using practical solutions identified by field studies and simulations
(2021-10-26)With increasing cancer incidence comes a higher demand for radiotherapy (RT). Resources available for RT, well-educated staff, and linear accelerators (linacs), are limited. To meet the increasing demand without violating ... -
Physiological roles of amyloid precursor protein in vivo - zebrafish as a model
(2021-10-26)Amyloid-beta precursor protein (APP) is an evolutionarily conserved transmembrane protein expressed in many different tissues. APP belongs to a gene family consisting of two other APP-like proteins (APLP1 and APLP2). APP ... -
Obesity, weight reduction treatment and IVF
(2021-10-26)Background: Obesity is a growing problem on a global scale and women with obesity have a higher risk for infertility and complications, for both mother and child, in pregnancy and birth. This has been shown both regarding ... -
The Role of FCGBP in Mucus - Structure, Processing and Function
(2021-10-26)In this thesis, a bottom-up approach was used to study the IgG Fc-binding protein (FCGBP), which next to the MUC2 mucin is the second main component of secreted mucus in small intestine and colon. FCGBP is also found in ... -
Sex steroid secretion during childhood in males - with focus on prematurity, birth size, and growth patterns
(2021-10-21)Aim: The overall aim of the thesis was to evaluate sex steroid secretion patterns during childhood in boys and to study how sex steroid concentrations relate to gestational age, birth weight, growth patterns, and adult ... -
Aspects of Chemotherapy in Prostate Cancer
(2021-10-19)Since 2004 chemotherapy has been a part of standard of care in prostate cancer (PC) and improved symptom control and survival has been demonstrated in metastatic castration-resistant PC. Whether docetaxel has benefits in ... -
Humeral fractures - Epidemiology, treatment and reoperations in the Swedish Fracture Register
(2021-10-15)Fractures are common, but the knowledge on outcomes, treatment methods or the actual number of fractures treated each year has been sparse. With the introduction of the Swedish Fracture Register (SFR) in 2011, the prospective ... -
Cognition and activity early after stroke
(2021-10-13)Introduction and aims: Cognitive impairment and dependency in activities of daily living (ADL) are common consequences of stroke. Due to a decrease in the length of hospital stay, assessment of these conditions ... -
Osteoporosis in murine SLE - Treatment with a tissue-selective estrogen complex
(2021-10)Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting mainly young women. Almost every organ in the body can be affected and SLE patients often suffer from co-morbidities such as cardiovascular ... -
Computational studies of mutational sequence signatures in cancer genomes
(2021-10-08)Cancer typically forms when mutational processes modify key cancer driver genes, resulting in positive selection and tumor growth. As such, mutational processes are at the core of the disease. Trinucleotide mutational ... -
Periarticular changes in association with osteoarthritis in the hip, knee or shoulder
(2021-10-08)The aim of this thesis was to evaluate the presence of degenerative changes in the periarticular tendons in association with osteoarthritis (OA) in the hip, knee or shoulder. Moreover, changes in bone mineral density (BMD) ... -
On dental implant failure and patient-related factors
(2021-10-08)Dental implants function as anchorage for dental prostheses. In a small number of cases, osseointegration fails to establish or be maintained around the implants, but the reasons for these failures are not yet fully ... -
Mechanisms underlying inflammation, symptoms and quality of life in ulcerative colitis
(2021-10-06)A substantial proportion of patients with ulcerative colitis (UC) in remission demonstrate gastrointestinal (GI) symptoms, despite the absence of ongoing inflammation in the colon. The underlying mechanisms of these symptoms ... -
Effect of Probiotics on Caries-related Variables
(2021-10-05)In relation to the caries disease, the aims of this thesis were to investigate the effect of probiotic drops on different caries-related variables in vivo (Papers I & III), on interference capability and genetic response ... -
Adaptation of ventricular repolarization to heart rate change in humans
(2021-10-01)Background: Life-threatening cardiac rhythm disturbances and sudden death are common manifestations of heart disease. Disturbances in electrical recovery (ventricular repolarization; VR) are important mechanisms behind ... -
Predictors of survival in cardiac arrest
(2021-10-01)Cardiac arrest (CA) refers to the cessation of cardiac function. Survival is around 30% for in-hospital cardiac arrest (IHCA), and 10% for out-of-hospital cardiac arrest (OHCA). Many factors influence survival, ranging ...