Sahlgrenska Academy / Sahlgrenska akademin: Recent submissions
Visas titlar 301-320 av 2677
-
Tissue engineering for novel female infertillity treatments: studies on small and large animal models
(2021-02-25)Introduction: As with any transplantation (Tx) procedure, uterus Tx is associated with risky donor surgery and adverse side-effects from immunosuppression. With the aim to bypass these risks, this thesis investigated uterus ... -
The role of head size in total hip arthroplasty - Dislocation, wear and cup stability
(2021-02-24)Large heads are used in total hip arthroplasty, with the aim of reducing the risk of dislocation, but there are concerns related to polyethylene wear, corrosion and cup loosening. Paper I is an observational study that ... -
The role of MBOAT7 on fatty liver disease
(2021-02-18)Non-alcoholic fatty liver disease (NAFLD) is the main health disorder in internal medicine, affecting one third of the population worldwide. Environmental and genetic factors contribute to NAFLD susceptibility and progression. ... -
The role of physical activity for recovery after surgical procedures
(2021-02-18)The aim of this thesis was to determine the association between and effect of preoperative physical activity and postoperative recovery after surgery due to gallbladder disease or colorectal cancer. Paper I examined the ... -
Management of late term pregnancy
(2021-02-17)Background: The optimal time point to intervene and induce labour in women with a low-risk pregnancy, in order to decrease perinatal adverse outcome, is up for debate. Some advocate for induction of labour (IOL) at 41 ... -
Registry-based studies of return to work after stroke - part of the work after stroke study (WASS)
(2021-02-15)Objectives. Stroke is one of the most common diseases and a main cause of disability both globally and in Sweden. Even though the risk increases with older age, stroke in the younger population is increasing and a substantial ... -
Neutrophil Function and Signaling Induced by Ligands for the Formyl Peptide Receptor 2
(2021-02-15)Neutrophil pattern recognition receptors belonging to the G-protein coupled receptor (GPCR) family play a role in the processes of initiation as well as resolution of inflammatory processes. Formyl peptide receptor 2 (FPR2) ... -
Price sensitivity and regional variation in health care
(2021-02-12)Understanding the consequences of current health policy is important in order to design and develop a health care system suitable for future challenges. The purpose of this thesis is to bring evidence on the determinants ... -
Fluid biomarkers of extracellular matrix remodelling across neurological diseases
(2021-02-12)Neurological diseases constitute a major health and socioeconomic issue. Despite an enormous amount of research going on globally, the prevalence and mortality of neurological disorders are still rising. This has placed a ... -
Antiretroviral treatment of HIV-1 in Sweden with focus on virological aspects
(2021-02-11)From a clinical standpoint, there are many factors to consider when optimizing the care for people living with HIV (PLWH). With help from clinical guidelines, most obstacles can be addressed. Expanded knowledge is however ... -
Hearing in early old age: current perspectives
(2021-02-08)Age related hearing loss is a public health concern that restricts the possibilities of older persons to lead a healthy, social and active life. The present thesis aims to provide contemporary perspectives on age related ... -
Molecular and genetic studies in high-risk neuroblastoma
(2021-02-04)Neuroblastoma is the most common and deadly cancer in the first year of life. Children with high-risk neuroblastoma have a very poor prognosis, despite heavy multimodal treatment, with less than 50% of 5 years of overall ... -
Characterization of immune cell profiles in meninges and brain parenchyma following injury in the developing mouse brain
(2021-02-04)Preterm newborns are particularly susceptible to complications such as hypoxia-ischemia (HI), which can result in brain injury and subsequent cognitive and/or motor function disabilities, including cerebral palsy. Immune ... -
Pregnancy in women with congenital heart disease
(2021-01-29)Abstract Background: The survival for children born with congenital heart disease (CHD) has increased and the majority reach adult age. Having a cardiac problem raise questions on the probability of successful pregnancies ... -
Learning aspects of out-of-hospital cardiac arrest and learning activities in basic life support - a study among laypersons at workplaces in Sweden
(2021-01-29)Abstract Background: Out-of-hospital cardiac arrest (OHCA) is one of the leading causes of death worldwide. Despite healthcare improvements, prevention for cardiovascular health, training in adult basic life support (BLS) ... -
The breast cancer microenvironment and cancer cell secretion - specific effects on cancer progression and subtypes of cancer cells
(2021-01-22)Breast cancer is the cancer form responsible for the most cancer-related deaths among women worldwide, and novel targeted therapies are highly needed. The tumor microenvironment consists of several components, including ... -
Irritable bowel syndrome - a disorder of gut-brain interaction
(2021-01-22)Irritable bowel syndrome (IBS) is a common and multifactorial functional gastrointestinal (GI) disorder characterized by altered gut-brain communication. Due to the complexity of gut-brain interactions, the aim of this ... -
Postoperative pain management in planned lumbar spine surgery: Implementing structural changes in a complex healthcare setting
(2021-01-18)BACKGROUND Poorly managed postoperative pain (POP) continues to cause suffering and prolong hospital care, affecting patients, individual health care professionals, and team strategies and attitudes. The impact on these ... -
Regulation of Human Mitochondrial DNA Replication and Transcription
(2021-01-18)Regulation of Human Mitochondrial DNA Replication and Transcription Majda Mehmedović Department of Medical Biochemistry and Cell biology, Institute of Biomedicine Sahlgrenska Academy, University of Gothenburg Gothenburg, ... -
Neurogenic bladder and bowel dysfunction - incontinence and life situation in adolescents and adults with spina bifida
(2021-01-07)Neurogenic bladder and bowel dysfunction - incontinence and life situation in adolescents and adults with spina bifida Magdalena Vu Minh Arnell Department of Pediatrics, Institute of Clinical Sciences Sahlgrenska ...