Sahlgrenska Academy / Sahlgrenska akademin: Recent submissions
Now showing items 321-340 of 2677
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Tick-borne encephalitis - clinical and virological aspects
(2021-01-05)Tick-borne encephalitis (TBE), an important central nervous system infection in Europe and Asia, is caused by the TBE virus (TBEV), which is mainly transmitted to humans through tick bites. This thesis studied data from ... -
Sambandet mellan kemiska exponeringar i arbetsmiljön och risken att utveckla ledgångsreumatism
(Avdelningen för samhällsmedicin och folkhälsa, Göteborgs universitet, 2020-12-21)Inledning: Ledgångsreumatism (Reumatoid artrit, RA) är en sjukdom som främst drabbar lederna, men som också kan påverka många andra organ, med till exempel hjärt-kärlsjukdom, lungsjukdom och vissa typer av blodcancer som ... -
Mass spectrometric analyses of proteoglycans - Novel tools for studying prohormones in insulin-producing cells
(2020-12-15)Proteoglycans (PGs) are proteins that carry one or more negatively charged glycosaminoglycan (GAG) chains. Proteoglycans have been identified in essentially all multicellular organisms, and are implicated in a wide range ... -
On the mortality of patients treated with dental implants: Association to age, degree of tooth loss, and treatment modality
(2020-12-15)Rehabilitation of partially or completely edentulous patients with implant-supported prostheses is a common treatment in dentistry. Clinical studies evaluating this type of treatment have largely focused on technical and ... -
Patient empowerment during the transition to adulthood in young persons with chronic conditions
(2020-12-08)During the transition to adulthood and adult care young persons with chronic conditions (CCs) are in need of developing the skills necessary to manage their condition, communicate with the healthcare provider, participate ... -
Polycystic ovary syndrome in a lifetime perspective
(2020-12-08)Background: Polycystic ovary syndrome (PCOS) is common, affecting 9-18% of women. PCOS is associated with symptoms due to hyperandrogenism and ovarian dysfunction, but is also associated with the metabolic syndrome including ... -
Cost-Effectiveness of Vaccination and the Value of Prevention
(2020-11-27)The overall aim of this thesis was to analyse the cost-effectiveness of vaccination of infectious diseases and to investigate the value of prevention, in a Swedish setting. This thesis consists of five studies. In Study ... -
Anaplastic lymphoma kinase activity, a therapeutic target, suppresses neuroblastoma cell differentiation
(2020-11-27)Neuroblastoma (NB) is the most common extracranial pediatric solid malignancy caused by the failed differentiation of precursor cells of the developing sympathetic nervous system. NB accounts for about 15% of childhood ... -
Exposure to household air pollution among women and children in Ethiopia: Socio-cultural factors and the association with airway health
(2020-11-27)Abstract Using solid fuel generates emissions of many health-damaging pollutants including inhalable fine particulate matter (PM2.5). Such exposure is known to cause morbidity and mortality in low- and middle-income ... -
Transcriptomic and functional studies of fusion oncogene-driven salivary gland tumors
(2020-11-25)Fusion genes are potent oncogenic drivers resulting from exchange of regulatory/coding sequences between two genes. They were originally identified in leukemias but are now recognized as key oncogenic events also in many ... -
Functional outcome and experiences concerning daily life after malunion of the distal radius and corrective osteotomy
(2020-11-25)BACKGROUND. Distal radius fractures are common injuries that occur at all ages. The commonest complication is that the fracture heals in malunion. This can negatively affect function and the ability to perform activities. ... -
Hållbart arbetsliv i bilindustrin: Vikten av psykosociala faktorer, kön och yrke
(Avdelningen för samhällsmedicin och folkhälsa, Göteborgs universitet, 2020-11)Syfte: Syftet med denna fall-kontroll studie var att undersöka sambandet mellan psykosociala faktorer och fortsatt arbete efter 62 års ålder i en grupp anställda inom bilindustrin. Metod: En inbjudan att delta i studien ... -
Oral leukoplakia, human papillomavirus and cancer transformation
(2020-11-20)Oral leukoplakia (OL) is clinically diagnosed as a white oral lesion that cannot be scraped of or diagnosed as any other type of oral lesion. OL has the potential to transform into oral squamous cell carcinoma (OSCC). The ... -
Neurobehavioral correlates of disinhibitory psychopathology
(2020-11-20)Disinhibitory psychopathology refers to maladaptive behavioral expressions stemming from problems with impulse control. Despite a robust association with antisocial and criminal behavior, knowledge about the neurobehavioral ... -
Att upprätthålla självbestämmande i palliativt skede på särskilt boende - en modell för att främja personcentrerad vård för äldre
(2020-11-20)The overall aim of the thesis was to develop a model that facilitates self-determination in the palliative phase in residential care. The three first studies constituted the ground for the model, which was developed in the ... -
A prevention and health promotion programme for persons with overweight in Primary Health Care Patient outcomes and nurses’ experiences in terms of weight, lifestyle, health and risk factors
(2020-11-20)Background: Primary Healthcare (PHC) is often the first point of contact for patients and thus considered the ideal place to address obesity and lifestyle issues. A weight reduction programme was developed to gain a better ... -
Pituitary Tumors - Epidemiology and the Diagnostic Value of 68Ga-DOTATOC PET
(2020-11-20)Pituitary neuroendocrine tumors (PitNETs) are considered common in the general population. However benign in most cases, these tumors can evoke dramatic morbidity in patients with aggressive tumor growth and/or excess ... -
Restrictive eating disorders: aetiological, epidemiological and neurodevelopmental aspects
(2020-11-20)Restrictive Eating Disorders (EDs), including Avoidant/Restrictive Food Intake Disorder (ARFID) and Anorexia Nervosa (AN), are characterised by severely restricted food intake, commonly leading to substantial weight loss ... -
Autism and ADHD in children with cerebral palsy
(2020-11-13)BACKGROUND: Autism spectrum disorder (autism) and attention-deficit/hyperactivity disorder (ADHD) are likely underdiagnosed in children with cerebral palsy (CP). Early identification of impairments is important for adequate ... -
Dental Anxiety: prevalence, measurements and consequences
(2020-11-11)The overall aim of this thesis was to gain knowledge about adults suffering from dental anxiety by studying the current prevalence of dental anxiety and concomitant factors, the impact of dental pain on everyday life ...