Sahlgrenska Academy / Sahlgrenska akademin: Recent submissions
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Acute respiratory infections among children in the Democratic Republic of Congo - nasopharyngeal pathogens, antibiotic resistance and vaccination
(2020-09-29)ABSTRACT Acute Lower Respiratory Infections (ALRI) remain a leading cause of morbidity and mortality among children in the Democratic Republic of the Congo (DR Congo). The pneumococcal conjugate vaccine PCV13 was ... -
Diagnosis and management of periprosthetic joint infections
(2020-09-18)Periprosthetic joint infection (PJI) is a severe complication to hip and knee arthroplasty surgery. In the light of its devastating implications for the affected patient, its great economic impact on the health care system ... -
Aspects of teamwork and intraoperative factors in the operating room
(2020-09-07)The work in high-risk environments like an operating room is complex. The operating team consist of many professions with different tasks cooperating towards a common goal, the performance of safe surgery. The operating ... -
Lipoproteins in Staphylococcus aureus infections
(2020-09-04)Staphylococcus aureus (S. aureus) infections remain a major challenge for the healthcare system, and new treatment options are highly demanded. S. aureus is a pathogenic microorganism, responsible for a broad range of ... -
Aplastic anemia - a population-based study of epidemiology, treatment, and prognostic factors
(2020-09-03)Background and aims. Aplastic anemia (AA) is a rare but life-threatening disease. The introduction of immunosuppressive treatment (IST) and hematopoietic stem cell transplantation (HSCT) has considerably improved the outcome ... -
Occupational engagement after stroke - a long-term perspective
(2020-09-03)Introduction: In the literature it is recognized that stroke can have lifelong consequences and that these consequences become evident in the occupations that constitute everyday life. With an increase in prevalence and ... -
Pathophysiology and treatment of Takotsubo Syndrome - insights from preclinical studies
(2020-09-03)ABSTRACT Background: Takotsubo syndrome (TTS), also recognized as “stress-induced cardiomyopathy (SIC)” and “broken heart syndrome”, is an acute cardiac failure syndrome characterized by transient regional ventricular ... -
Appetite-regulating peptides and natural rewards: emphasis on ghrelin and glucagon-like peptide-1
(2020-09-02)Evolutionary conserved natural behaviors, such as foraging and sexual behaviors, are strongly associated with reward processes. Brain areas important for reward processes include, but are not limited to, the nucleus accumbens ... -
The Nordic Expert Group for Criteria Documentation of Health Risks from Chemicals. 153. Occupational chemical exposures and cardiovascular disease
(Samhällsmedicin och folkhälsa, Göteborgs universitet, 2020-08-28)The main task of the Nordic Expert Groupfor Criteria Documentation of Health Risks from Chemicals (NEG) is to produce criteria documents to be used by the regulatory authoritiesasthescientific basis ... -
Population-based studies of brain tumor surgery: surgical outcome and prognostic factors
(2020-08-27)Neurosurgery is the cornerstone in the treatment of a majority of brain tumors. Surgery can sometimes cure or delay tumor progression. However, surgery is associated with risks, and adequate information about the anticipated ... -
Diagnostic aspects of skin cancer and lichen sclerosus studied with laser scanning microscopy
(2020-08-20)Histopathologic examination of tissue biopsies is the current gold standard for the diagnosis of dermatological problems. Similarly, in oncology, sentinel lymph node (SLN) biopsy is the state-of-the-art diagnostic method ... -
Predicting mortality by comorbidity for patients with hip arthroplasty: Prospective observational register studies of a nationwide Swedish cohort
(2020-08-19)INTRODUCTION: Patients with total hip arthroplasty (THA) due to osteoarthritis (OA) are usually healthy, some with a remaining lifetime of several decades after surgery. Patients with hip arthroplasty due to a femoral ... -
Optimizing postoperative radiation therapy in prostate cancer: focus on side-effects, practical implementation and dose distribution
(2020-08-18)Optimizing postoperative radiotherapy in prostate cancer: focus on side effects, practical implementation and dose distribution Karin Braide, MD Department of Urology, Institute of Clincal Sciences Sahlgrenska Academy, ... -
The fight against time in prehospital cardiac arrest - a true medical emergency
(2020-08-18)ABSTRACT Background: The chances of survival after an out-of-hospital cardiac arrest (OHCA) are one in ten. The majority of survivors have no or relatively mild neurological sequelae. Interventions are time critical and ... -
Klimat och hälsa - En kunskapssammanställning
(Samhällsmedicin och folkhälsa, Göteborgs universitet, 2020-06-05)Sammanfattningsvis anser vi att klimatförändringarna är ett stort hot mot vår hälsa. De största direkta hoten utgörs av brist på mat och rent vatten, värmeböljor och ändrat sjukdomspanorama. De sekundära effekterna kan ... -
Time-lapse technology in the IVF laboratory. Assessing safety and human embryo development
(2020)Background: Time-lapse monitoring of human embryos is becoming increasingly utilized in clinical IVF laboratories. This technology allows for uninterrupted, continuous observation of embryo development without having to ... -
Paracrine control of glucagon secretion in the pancreatic α-cell: Studies involving optogenetic cell activation
(2020-06-12)ABSTRACT The mechanisms controlling glucagon secretion by α-cells in islets of Langerhans were studied. We generated mice with the light-activated ion channel ChR2 specifically expressed in β-, α-, and δ-cells, and ... -
A Podocyte view on RhoGTPases and actin cytoskeleton regulation
(2020-06-11)Proteinuria is a hallmark symptom of chronic kidney disease, that if left to persist constitutes a risk for progression of disease. Symptomatic treatment aiming at decreasing proteinuria is therefore standard practice. ... -
Recombinant mucin-type proteins as tools for studies on the interactions between Helicobacter pylori and its carbohydrate receptors
(2020-06-11)Glycan-protein interactions are important in pathogen adhesion and infections. H. pylori has adhesins which enables it to bind to glycans on the gastric mucosa and, in the long run, cause gastric cancer. The reported current ... -
Comprehending the Comprehensive Geriatric Assessment. Feasibility, outcomes and experiences of frail older people
(2020-06-04)ABSTRACT Despite existing knowledge on how to approach frail people in health care, the care they receive is commonly not designed to meet their complex needs and support them in maintaining their activities of daily ...