Sahlgrenska Academy / Sahlgrenska akademin: Recent submissions
Visas titlar 721-740 av 2677
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Hypertension, Atrial Fibrillation and Aldosteronism - A study of interplay, predictors and outcome
(2018-03-12)Background: Atrial fibrillation (AF) is the most common significant arrhythmia, affecting almost 3% of the adult population in Sweden. Although AF is associated with increased risk of lower quality of life, heart failure, ... -
Prognostic impact of coronary microvascular funtion in patients with ischemic heart disease.
(2018-03-09)Background: Ischemic heart disease is the leading cause of death globally. Despite recent advances in interventional and medical therapies, survivors of myocardial infarction are at high risk of recurrent cardiovascular ... -
Predictors of Outcome after Anterior Cruciate Ligament Reconstruction
(2018-03-02)An anterior cruciate ligament (ACL) injury is one of the most common injuries to the knee joint. It is also one of the most researched areas within sports medicine, orthopedics and physical therapy. The goal of this thesis ... -
Mechanisms of intestinal tumor initiation and progression in ApcMin mouse model of colorectal cancer
(2018-03-02)Colorectal cancer (CRC) is a cancer that occurs in the colon or rectum and is one of the most common cancer forms and a leading cause of cancer death in the Western world. The majority of CRCs are caused by inherited or ... -
Endosonography and pretreatment tumor profiling - from sampling, staining, to sequencing
(2018-03-01)Background and aims: Endosonography-guided fine needle aspiration (EUS-FNA) is imperfect in diagnosing solid pancreatic lesions (SPL) and subepithelial lesions (SEL) including gastrointestinal stromal tumors (GIST). In ... -
Evaluation of the Endo-Lysosomal System and the Ubiquitin-Proteasome System in Neurodegenerative Diseases
(2018-02-27)Neurodegeneration is the process of neuronal cell loss where the symptoms will reflect the regions affected. Neurodegenerative disorders including Alzheimer’s disease (AD), Parkinson’s disease (PD) and frontotemporal ... -
Targeting NOX2 in cancer
(2018-02-27)Reactive oxygen species (ROS) are short-lived, toxic derivatives of oxygen that are produced during mitochondrial respiration and by NADPH oxidases (NOX). By enzymatically generating ROS, the myeloid cell NOX2 plays a ... -
SÄKRA BYGGET - Om säkerheten i svensk och dansk byggindustri - och hur den kan förbättras.
(Arbets- och Miljömedicin, 2018-02-23)I SveDan-projektet fann vi att skillnaden i frekvensen dödsolyckor i svensk och dansk byggindustri åren 1993-2012 var 45%. Syftet med SveDan-projektet var att i ett dansk-svenskt forskarsamarbete i en jämförande studie i ... -
Epidemiology, diagnostics and treatment of non-melanoma skin cancers
(2018-02-23)Skin cancer, including malignant melanoma and non-melanoma skin cancer (NMSC), is a growing problem due to the increasing incidence in Sweden and in other Caucasian populations. NMSCs are diagnosed as often as all other ... -
Longitudinal outcome following total hip replacement. Time trends, sequence of events and study of factors influencing implant survival and mortality
(2018-02-23)Osteoarthritis of the hip is a common, debilitating and symptomatic joint disease. The disabling symptoms can be successfully treated with a total hip replacement (THR). It is known that the majority of patients do well ... -
The fearful patient in routine dental care
(2018-02-22)Background: Managing dental fear is a daily challenge in dental care. The overall aims of this thesis were to study the attitudes of dental health professionals to fearful dental patients, and their skills and strategies ... -
Methylome and Transcriptome Profiling of Hepatocytes Derived from Human Pluripotent Stem Cells
(2018-02-22)Six hundred million people suffering from liver diseases worldwide of which the lethality is two million. Freshly isolated hepatocytes from the liver have been used for transplantation purposes and are extensively used to ... -
Women with type 1 diabetes during pregnancy and postpartum Well-being and diabetes management
(2018-02-19)Type 1 diabetes mellitus (T1DM) is associated with increased medical risks during pregnancy and birth. To minimize the risks and increase the possibility of a healthy offspring, blood glucose levels near normal are required. ... -
On prediction in orthognathic surgery. Analysis of 2D and 3D techniques from multiple perspectives
(2018-02-15)The aim of the present thesis was to compare two different prediction methods in orthognathic treatment of dentofacial deformities and severe malocclusions. The comparison was made between a two-dimensional (2D) and a ... -
On dental caries and socioeconomy in Swedish children and adolescents - Clinical and register-based studies
(2018-02-15)The overall aim was to analyze the dental caries experience among Swedish children and adolescents and explore it with respect to demographic and socioeconomic factors. Study I is a longitudinal clinical study of 271 ... -
Early detection of ESSENCE in Japanese 0-4-year-olds. Studies of neurodevelopmental problems in the community and in clinics
(2018-02-14)BACKGROUND: Early identification of children with neurodevelopmental problems/ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations) is a critical issue both in the community and in clinical ... -
The percutaneous implant. The effects of design, host site and surgery on the tissue response
(2018-02-14)This research project focuses on the multiple challenges associated with implants that breach the skin. The role of device design, host site, and surgical approach on tissue response and outcome are evaluated, experimentally ... -
Comprehensive analysis of structural genomic alterations in cancer
(2018-02-13)The transformation of a normal cell into a cancer cell involves the accumulation of somatic DNA alterations that confer growth and survival advantages. These genomic alterations can be different in terms of pattern and ... -
Counting deaths, accounting for lives
(2018-02-06)Half of the world’s deaths and their causes are never recorded by virtue of the under-resourced civil registration and vital statistics (CRVS) systems which limits capacity of health systems to respond to population needs. ... -
Renal denervation in patients with resistant hypertension
(2018-02-05)BACKGROUND Catheter-based renal denervation (RDN) is a potential modality in the treatment of patients with resistant hypertension (RH). The biological effects of RDN are not fully comprehended and studies examining its ...