Sahlgrenska Academy / Sahlgrenska akademin: Recent submissions
Now showing items 581-600 of 2677
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Anterior Cruciate Ligament Reconstruction - Early predictors of outcome
(2019-03-21)The rupture of the anterior cruciate ligament (ACL) is a serious injury, often resulting in functional instability and increased laxity of the knee joint. Patients suffering an ACL injury run the risk of further ... -
Children with spina bifida and their mothers in Palestine. Lived experiences, self perceived health and sense of coherence
(2019-03-20)ABSTRACT The overall aim in this thesis was to describe the lived experiences of children with spina bifida (SB) and their mothers while living under specific social and cultural conditions in West Bank, Palestine. A ... -
Isolation Strategies and Proteomic Characterization of Extracellular Vesicles
(2019-03-15)“Extracellular vesicles” is the collective term used to describe vesicular entities that are released from cells into the extracellular environment. These vesicles are composed of a delineating lipid membrane and its cargo ... -
Epigenetics of paediatric glioma stem cells; focusing on exosomes, miRNAs and DNA methylation
(2019-03-14)Tumours in the central nervous system are accountable for the majority of cancer-related deaths in children. Glioblastoma multiforme, one of the deadliest of the central nervous system tumours, is partly driven by glioma ... -
Long-term survival and prognostic factors in endometrial cancer - a populationbased cohort study
(2019-03-14)Aims: The over-all aims of this thesis were to evaluate the associations between prognostic factors and excess mortality rate, between socioeconomic and immigrant status and incidence rate, in endometrioid (EEC) and ... -
Intimate partner violence, sociodemographic factors and mental health among population based samples in Sweden
(2019-03-13)Aims: To explore the prevalence of Intimate Partner Violence (IPV) and its association with sociodemographic factors, symptoms of depression, perceived need for mental care and primary health care utilization. Another ... -
The postsynaptic protein neurogranin: a new item in the Alzheimer’s disease biomarker toolbox
(2019-03-13)Alzheimer’s disease (AD) is the most common form of dementia affecting more than 50 million people worldwide today and is characterised by progressive cognitive decline. One of the earliest events in AD, which is also ... -
Pathophysiological regulation of white adipocyte exocytosis of different adiponectin molecular forms
(2019-03-06)In this thesis we have identified mechanisms involved in the exocytosis of different adiponectin molecular forms in health and in metabolic disease. We have also studied similarities and differences in depot-specific ... -
Small intestinal neuroendocrine tumours - Disease models, tumour development, and remedy
(2019-03-06)Small intestinal neuroendocrine tumours (SINETs) are malignant neoplasms which at the time of diagnosis often present with distant metastasis. The field of SINET research faces several challenges. There is a lack of ... -
To predict results of breast cancer therapy
(2019-03-06)We have used the almost complete national Swedish Cancer register, regional quality management register and one randomized adjuvant endocrine trial to study, the effect of radiotherapy in breast cancer with 1-3 positive ... -
Prognostic factors and tumor treatments in hepatocellular cancer
(2019-03-04)Background: Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related death worldwide. Prognosis is related to tumor burden, liver function, and performance status as well as treatment factors. ... -
Study the role of patient-specific mutations by genetic disease modeling
(2019-03-01)Many genetic diseases inherited in a dominant fashion have a complex pathological pattern. TOR1A mediated Dystonia-1 (DYT1) is an example of incomplete penetrance, affecting only a third of the carriers. DYT1 is an early-onset ... -
En svensk arbetsmiljöhistoria – Arbetsmiljöinstituten och företagshälsovården
(Arbets- och miljömedicin, Göteborgs universitet, 2018-12-15)I Arbete och Hälsa har det under de första 50 åren sedan starten 1967 publicerats 1076 artiklar och rapporter. Innehållet speglar till viss del hur arbetsmiljön har förändrats under dessa år. Redan tidigt i industrialiserings ... -
Regulatory T cells and mucosal-associated invariant T cells in colon adenocarcinomas; Phenotype and function
(2019-02-27)In many solid cancers, and also in colon adenocarcinomas, an increased accumulation of lymphocytes is beneficial for the patient. However, tumor-infiltrating immune cells may be either pro- or anti-tumorigenic and the ... -
Childhood Body Mass Index and Pubertal Timing - Changes over time and associations with adult cardiovascular mortality
(2019-02-21)Puberty in boys has long been an under-investigated area of research mainly due to the lack of an easily available pubertal marker, corresponding to menarche for girls. Using a unique, large, population-based cohort, ... -
Barnfetma och Metabola Syndromet hos förskolebarn - tidiga faktorer och identifiering av riskindivider från ett longitudinellt perspektiv
(2019-02-15)Background: Overweight and obesity have increased worldwide and affect children at ever younger ages, resulting in cardiovascular disease and type 2 diabetes even in adolescents. This illustrates the importance of identifying ... -
Intracranial volume in neuroimaging: estimation and use in regional brain volume normalization
(2019-02-15)The aim of this thesis is to validate methods for estimation of intracranial volume in magnetic resonance images and to improve our understanding of the effect of intracranial volume normalization. To achieve the first ... -
Midwives’ Collective Attitude towards Labour Pain: Mixed Methods Research
(2019-02-08)Background: The majority of women in Jordan give birth in public hospitals where midwives are the main birth attendants. Although most women have trust in their midwives, studies have reported women’s dissatisfaction with ... -
Aspects of Communication, Language and Literacy in Autism Child Abilities and Parent Perspectives
(2019-02-07)The main aim of this thesis was to investigate literacy, ‘theory of mind’ (ToM) and narrative ability in children who had screened positive for autism spectrum disorders (ASD) (comprehensively assessed for neuropsychiatric ... -
Long-term outcomes of obsessive-compulsive disorder in children and adolescents
(2019-02-07)Aim: The overall aim of this thesis is to investigate the long-term course and outcome of pediatric OCD following evidence-based treatment of pediatric OCD. Outcome is assessed with regard to severity of OCD symptoms ...