Institute of Neuroscience and Physiology / Inst för neurovetenskap och fysiologi: Recent submissions
Visas titlar 401-420 av 437
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Non-invasive ultrasound-based cardiovascular imaging in mouse models of atherosclerosis
(2008-03-18)Atherosclerosis is a chronic multi-factorial vascular disease. It generally requires large clinical settings and over many years to study the disease progression in man. Genetically modified mouse models of atherosclerosis ... -
Cytokines in Metabolic Functions
(2008-02-28)During infections, circulating cytokines are largely produced by immune cells. In healthy obese individuals, large parts of these circulating cytokines are produced in adipose tissue, for instance by macrophages that have ... -
On the Autonomic Control of Blood Flow and Secretion in Salivary Glands. Functional and morphological aspects on muscarinic receptor subtypes in different species.
(2008-02-25)Parasympathetic nervous activity is the principal stimulus for evoking fluid responses within salivary glands. Concomitantly to the onset of this response, the blood flow increases. The responses, in particular the ... -
Blood and CSF biomarkers for investigation of the immunopathogenesis of relapse in Multiple Sclerosis
(2008-02-15)Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). MS usually starts with a relapsing-remitting course (RRMS) that later converts into a secondary progressive phase (SPMS). While inflammation ... -
Genetic association studies in stroke
(2008-01-11)Stroke is the third most common cause of death and the most common cause of disability in adults in developed countries. It is a complex disease in which genetic and environmental factors make about equal contributions. A ... -
Cognition and social behaviour in schizophrenia: An animal model investigating the potential role of nitric oxide
(2007-11-27)Cognitive deficits are the single strongest predictor of functional outcome in patients with schizophrenia. Furthermore, these deficits are not satisfactorily alleviated by available antipsychotic treatment. Functional ... -
Dopaminergic stabilizers for the treatment of schizophrenia. Rat studies focusing on negative symptoms and mechanisms of action
(2007-11-21)Schizophrenia is a severe mental disorder manifested by positive, negative and cognitive symptoms. Current antipsychotic drugs have poor effects on negative and cognitive symptoms, thus necessitating the development of new ... -
22q11 Deletion Syndrome. Neuropsychological and Neuropsychiatric Correlates. A Clinical Study of 100 Cases
(2007-11-12)Objectives: Examine the prevalence and type of Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity-Disorder (AD/HD), Learning Disability (LD), behavioural profile, intellectual ability/profile, and executive ... -
Alzheimer’s Disease: effect of Tau-related genes on the pathology, neurochemistry and risk of disease
(2007-11-07)Alzheimer’s disease (AD) is the most common form of dementia in the elderly. The predominant sporadic form of AD is a genetically complex disorder probably involving a combination of genetic factors together with environmental ... -
Virtual Rehabilitation - Implications for Persons with Stroke
(2007-09-24)Aims: The purpose of this thesis was to investigate the effects of Virtual Reality technology and haptics for stroke rehabilitation. Aims were to assess motor training in the so called chronic phase after stroke and to ... -
Piperaquine - Bioanalys, drug metabolism and pharmacokinetics
(2007-09-14)Malaria is one of the most abundant parasitic diseases in the world affecting many of the poorest economies. The estimated prevalence is 300 to 700 million clinical episodes each year with up to 3 million deaths. Piperaquine ... -
Plasticity of the developing glutamate synapse in the hippocampus
(2007-08-21)Synapses are highly plastic, i.e. they have the ability to change their signaling strength both in the short- and long-term (e.g. long-term potentiation - LTP) in response to specific patterns of activity. In the developing ... -
Studies of biochemical brain damage markers in patients at a neurointensive care unit
(2007-06-20)Physical examination is the basic and most important tool in medical practice. However, at a neurointensive care unit, neurological status can sometimes be difficult to evaluate due to sedation or impaired consciousness. ... -
Sensory and secretory responses to intestinal distension; implications for the pathophysiology of the irritable bowel syndrome
(2007-06-18)Irritable bowel syndrome (IBS) is a common gut disorder, characterized by abdominal pain and/or discomfort associated with disturbed bowel habits. The pathophysiology of IBS is complex and still largely unknown, although ... -
NEURAL STEM/PROGENITOR CELLS IN THE POST-ISCHEMIC ENVIRONMENT: Proliferation, Differentiation and Neuroprotection
(2007-06-04)Stroke is one of the leading causes of chronic disability and death in the Western world. Today, no treatment can repair the cellular loss associated with an ischemic lesion. However, the discovery and dynamic regulation ... -
The cholinergic-dopaminergic reward link and addictive behaviours: special emphasis on ethanol and ghrelin
(2007-05-16)An important part of the reward systems is the cholinergic-dopaminergic reward link. This reward link has been proposed to be involved in reward and motivated behaviours. It encompasses a cholinergic input from the ... -
Microglial Glutamate Transporters - Regulation of Expression and Possible Physiological Functions
(2007-05-15)Microglia are considered as the immunocompetent cells of the central nervous system (CNS). Being the first line of defence, they have prominent roles in monitoring the homeostasis and the extracellular milieu and can rapidly ... -
Imaging of coronary artery function and morphology in living mice - applications in atherosclerosis research
(2007-05-04)Atherosclerosis in the coronary arteries is the major reason for myocardial infarction and cardiovascular death. In the clinic, several imaging systems make it possible to study coronary artery function and morphology ... -
Mild stroke - consequences in everyday life, coping and life satisfaction.
(2007-04-25)Abstract Aim: The aim of this thesis was to explore the life situation one year after an apparently mild stroke, and to compare life satisfaction between patients and their spouses. Method: Seventy-five patients with ... -
Autism syndromes in three behavioural phenotype conditions. A clinical psychiatric study of 76 individuals with Möbius sequence, CHARGE syndrome, and oculo-auriculo-vertebral spectrum
(2007-04-12)AUTISM SYNDROMES IN THREE BEHAVIOURAL PHENOTYPE CONDITIONS A clinical psychiatric study of 76 individuals with Möbius sequence, CHARGE syndrome, and oculoauriculovertebral spectrum Maria Johansson Institute of ...