Institute of Neuroscience and Physiology / Inst för neurovetenskap och fysiologi: Recent submissions
Visas titlar 61-80 av 437
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Autism and ADHD in children with cerebral palsy
(2020-11-13)BACKGROUND: Autism spectrum disorder (autism) and attention-deficit/hyperactivity disorder (ADHD) are likely underdiagnosed in children with cerebral palsy (CP). Early identification of impairments is important for adequate ... -
Treatments and outcomes in bipolar disorder
(2020-11-02)Bipolar disorder is defined by recurring mood episodes and patients have a markedly increased risk of suicide. Pharmacological and psychological treatments for bipolar disorder have proven efficacy in clinical trials ... -
On parental self-efficacy in families with paediatric cataract and its clinical implications
(2020-11-02)Introduction: Parent participation is implicit in all paediatric care. Responsibility for the treatment after cataract surgery (contact lenses, patching, eye drops and being alert to signs of complications) mainly lies ... -
Postural balance, anxiety and motor function after stroke, at a very early supported discharge with continued rehabilitation
(2020-10-23)The overall aim of this thesis was to investigate postural balance, anxiety and motor function the first year after stroke and whether postural balance, anxiety and motor function was different at the intervention of Very ... -
Revealing the complex nature of amyloid beta and its relation to dementia
(2020-10-20)Alzheimer disease (AD) is the most common type of dementia and characterized by the accumulation of amyloid plaques in the extracellular space of the brain parenchyma. Amyloid plaques consist of amyloid beta peptides (Aβ). ... -
Serotonin in Fear and Anxiety
(2020-10-16)That the neurotransmitter serotonin (5-HT) has a central role in fear and anxiety is supported by numerous experimental and clinical studies. Arguably the most illustrative example is the effect of serotonergic-acting ... -
Physical activity on prescription in primary care. Impact on physical activity level, metabolic health and health-related quality of life, and its cost-effectiveness - a short- and long-term perspective
(2020-10-08)Non-communicable diseases (NCDs) are the leading cause of death globally and one of the major health challenges of the 21st century. In Sweden, NCDs are estimated to account for 90 % of all deaths. Strong evidence indicates ... -
Studies on the Etiology of Parkinson's disease
(2020-10-01)ABSTRACT Parkinson’s disease (PD) is the second most common neurodegenerative disorder in the world and affects around 1% of the population over 60 years of age. The main symptoms of PD include bradykinesia, resting ... -
Occupational engagement after stroke - a long-term perspective
(2020-09-03)Introduction: In the literature it is recognized that stroke can have lifelong consequences and that these consequences become evident in the occupations that constitute everyday life. With an increase in prevalence and ... -
Appetite-regulating peptides and natural rewards: emphasis on ghrelin and glucagon-like peptide-1
(2020-09-02)Evolutionary conserved natural behaviors, such as foraging and sexual behaviors, are strongly associated with reward processes. Brain areas important for reward processes include, but are not limited to, the nucleus accumbens ... -
Population-based studies of brain tumor surgery: surgical outcome and prognostic factors
(2020-08-27)Neurosurgery is the cornerstone in the treatment of a majority of brain tumors. Surgery can sometimes cure or delay tumor progression. However, surgery is associated with risks, and adequate information about the anticipated ... -
Paracrine control of glucagon secretion in the pancreatic α-cell: Studies involving optogenetic cell activation
(2020-06-12)ABSTRACT The mechanisms controlling glucagon secretion by α-cells in islets of Langerhans were studied. We generated mice with the light-activated ion channel ChR2 specifically expressed in β-, α-, and δ-cells, and ... -
A Podocyte view on RhoGTPases and actin cytoskeleton regulation
(2020-06-11)Proteinuria is a hallmark symptom of chronic kidney disease, that if left to persist constitutes a risk for progression of disease. Symptomatic treatment aiming at decreasing proteinuria is therefore standard practice. ... -
Comprehending the Comprehensive Geriatric Assessment. Feasibility, outcomes and experiences of frail older people
(2020-06-04)ABSTRACT Despite existing knowledge on how to approach frail people in health care, the care they receive is commonly not designed to meet their complex needs and support them in maintaining their activities of daily ... -
On Cyclodeviation - Strategies for Investigation, Management and quality of Life
(2020-06-04)Introduction: Cyclodeviation is a form of strabismus that is not externally visible. It is measured subjectively and in degrees, as incyclotorsion or excyclotorsion. The perception of subjective tilting does not always ... -
Shedding light on cognitive control
(2020-05-18)This thesis aimed to investigate the ability to adjust cognitive processes and behavior, i.e., cognitive control, and its related functional activity in the cortex. The optical imaging technique functional near-infrared ... -
Development of MALDI Mass Spectrometry Imaging Methods for Probing Spatial Lipid Biochemistry of Amyloid Plaques in Alzheimer's Disease
(2020-05-18)Alzheimer’s disease (AD) is the most prevalent cause of neurodegenerative dementia. Aggregation of amyloid β (Aβ) peptides into extracellular Aβ plaques is one of the major neuropathological features of AD. However, Aloysius ... -
Internationally adopted children with unilateral cleft lip and palate - longitudinal perspectives on speech production and language ability
(2020-05-13)Many children with cleft lip and palate have been adopted to Sweden. Most had had no palatal closure performed in their native countries and received their first palatal surgery in Sweden while acquiring a new first language. ... -
Natural course and long-term prognosis in idiopathic Normal Pressure Hydrocephalus - the effect of delayed surgery and clinical factors on outcome and survival
(2020-05-07)Idiopathic Normal Pressure Hydrocephalus, iNPH, causes gait and balance difficulties, urinary incontinence and cognitive decline in mainly older persons and is treatable by insertion of a cerebrospinal fluid diverting ... -
Virtual reality based kinematics for assessment of post-stroke upper limb function
(2020-04-28)The main scope of this thesis was to develop a method for assessing the upper limb sensorimotor function following stroke using virtual reality-based technique. The studies reported in this thesis included 67 individuals ...