Institute of Neuroscience and Physiology / Inst för neurovetenskap och fysiologi: Recent submissions
Now showing items 121-140 of 437
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Wearable sensors for monitoring epilepsy and Parkinson´s disease
(2019-04-11)Introduction: Epilepsy and Parkinson’s disease (PD) are conditions where management would benefit greatly from monitoring symptoms over longer time periods in natural everyday environments instead of only intermittent ... -
Direct triaging to physiotherapist in primary care - development and evaluation of a triage model
(2019-04-05)Background: There is evidence that early contact with physiotherapists leads to advantages for patients with musculoskeletal disorders. Many patients, however, initially seek contact with general practitioners (GPs) within ... -
The postsynaptic protein neurogranin: a new item in the Alzheimer’s disease biomarker toolbox
(2019-03-13)Alzheimer’s disease (AD) is the most common form of dementia affecting more than 50 million people worldwide today and is characterised by progressive cognitive decline. One of the earliest events in AD, which is also ... -
Pathophysiological regulation of white adipocyte exocytosis of different adiponectin molecular forms
(2019-03-06)In this thesis we have identified mechanisms involved in the exocytosis of different adiponectin molecular forms in health and in metabolic disease. We have also studied similarities and differences in depot-specific ... -
Intracranial volume in neuroimaging: estimation and use in regional brain volume normalization
(2019-02-15)The aim of this thesis is to validate methods for estimation of intracranial volume in magnetic resonance images and to improve our understanding of the effect of intracranial volume normalization. To achieve the first ... -
Aspects of Communication, Language and Literacy in Autism Child Abilities and Parent Perspectives
(2019-02-07)The main aim of this thesis was to investigate literacy, ‘theory of mind’ (ToM) and narrative ability in children who had screened positive for autism spectrum disorders (ASD) (comprehensively assessed for neuropsychiatric ... -
Long-term outcomes of obsessive-compulsive disorder in children and adolescents
(2019-02-07)Aim: The overall aim of this thesis is to investigate the long-term course and outcome of pediatric OCD following evidence-based treatment of pediatric OCD. Outcome is assessed with regard to severity of OCD symptoms ... -
On the Effects of Serotonin Reuptake Inhibitors in Major Depression
(2019-01-25)This thesis focuses on the antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) and how these are reflected by the Hamilton Depression Rating Scale (HDRS). To this end, we have assembled a large data ... -
Glucagon-like peptide-1 and alcohol-mediated behaviors in rodents
(2019-01-18)Alcohol use disorder (AUD) is a serious cause of morbidity and mortality. However, due to the limited efficacy of existing pharmacotherapies, further investigations of potential neurochemical targets are required to define ... -
Advanced renal cell carcinoma - The role of orellanine and associated therapeutic challenges
(2018-12-20)Orellanine is a fungal nephrotoxin selectively toxic to the human tubular epithelial cells (HTEC) of the kidney nephrons leading to kidney failure. Patients treated with renal replacement therapy after orellanine poisoning ... -
Let’s stay in touch! Remote communication for people with communicative and cognitive disabilities
(2018-12-13)Introduction: Being able to use remote communication through digital channels is a prerequisite for participation in contemporary society, but some people have difficulties in accessing it. Aim: The overall aim was to ... -
Natural History of Human Papillomavirus Infections and Other Sexually Transmitted Infections in Rwanda-Immunological Aspects of the Uterine Cervix
(2018-11-23)Objective: Cervical cancer stands for the predominant cause of cancer death among Rwandan women. Chronic Human Papillomavirus (HPV) infection constitutes the main risk factor. We here assessed the prevalence and incidence ... -
Influence of serotonin on anxiety-like behavior in rat
(2018-11-05)It is well-established that serotonin is involved in the regulation of mood and behaviour, partly implied by the therapeutic effect of prolonged treatment with selective serotonin reuptake inhibitors (SSRI) on mood and ... -
Timely treatment in stroke and TIA
(2018-10-26)In acute stroke, the effect of both acute treatments and secondary prevention is timedependent. Patients´ delay is an important obstacle to acute recanalization therapy for stroke. To decrease this delay, a stroke ... -
Collaborative challenges in integrated care: Untangling the preconditions for collaboration and frail older people's participation
(2018-10-26)Introduction: Frail older people often have comprehensive and complex care needs involving different caregivers and professionals. Deficits in integrated caretaking often result in hospital readmission. Aim: The aim of ... -
On oxytocin and social behavior
(2018-10-19)Complex social cognitive processes underlie social behavior. Oxytocin has long been recognized as crucial in social behavior in animals, but its role in regulating human social cognition and behavior is less clear, ... -
Cerebrospinal fluid peptidomics: discovery of endogenous peptides as biomarkers of Alzheimer's disease
(2018-10-02)Neurodegenerative diseases (NDs), the most prominent example of which is Alzheimer’s disease (AD), has turned out to be among the greatest challenges for modern medicine. Common characteristics of NDs involve the aggregation ... -
Capturing the experience of health among persons aging in a migration context - Health promotion interventions as means to enable health and occupations in daily life
(2018-09-28)Aim: The overall aim of this thesis was to increase our understanding of health in everyday life among older persons aging in migration, and to evaluate the outcome of a health promotion intervention on sense of coherence, ... -
Exercise-based cardiac rehabilitation, physical fitness, and physical activity in cardiac disease
(2018-09-12)Background: Evidence suggests that individualised exercise-based cardiac rehabilitation should be offered to patients with ischemic heart disease and chronic heart failure (HF) because it improves physical fitness and ... -
Learning for life - How children with unilateral spastic cerebral palsy learn to master bimanual activities
(2018-09-03)Background: For children with unilateral spastic cerebral palsy (USCP), activities in daily life pose a challenge due to reduced function in one hand. Aim: To study the development of hand function and occupational ...