Institute of Neuroscience and Physiology / Inst för neurovetenskap och fysiologi: Recent submissions
Now showing items 141-160 of 437
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On the Effects of Sensory Noise in ADHD
(2018-08-31)Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders amongst children of the developed world. The main symptoms of the disorder include hyperactivity, inattention and ... -
Bringing MEG towards clinical applications
(2018-08-21)Magnetoencephalography (MEG) is a passive, non-invasive functional neuroimaging technique for recording magnetic fields generated by neuronal currents in the brain. MEG provides a unique capability to map the electrophysiology ... -
Muscle strength and resistance exercise in women with fibromyalgia - a person-centered approach
(2018-05-15)Fibromyalgia (FM) is characterized by generalized pain and associated with impaired physical capacity and activity limitations. Low-intensity exercise has been shown to be a safe way to exercise without risking an increase ... -
Adult Chiari I malformation - Clinical presentation and surgical outcomes
(2018-04-04)Background Chiari I malformations (CMIs) are hindbrain anomalies that are characterized by cerebellar tonsillar ectopia. The typical presentation is an occipital headache that worsens with exertion. In this thesis, I focus ... -
Body composition in women of reproductive age and during pregnancy. Method comparisons and gestational changes
(2018-03-28)Body composition measurements can contribute to assessment of nutritional status, both for clinical use and for research purpose. During pregnancy, body composition measurement is complicated by decreased density of the ... -
Biomarkers in Multiple Sclerosis - Monitoring disease activity and treatment afficacy
(2018-03-21)The pathophysiology of multiple sclerosis (MS) is complex with the presence of inflammation and neurodegeneration in all stages of the disease. The disease course, treatment response and outcome are highly variable in MS. ... -
Predictors of Outcome after Anterior Cruciate Ligament Reconstruction
(2018-03-02)An anterior cruciate ligament (ACL) injury is one of the most common injuries to the knee joint. It is also one of the most researched areas within sports medicine, orthopedics and physical therapy. The goal of this thesis ... -
Evaluation of the Endo-Lysosomal System and the Ubiquitin-Proteasome System in Neurodegenerative Diseases
(2018-02-27)Neurodegeneration is the process of neuronal cell loss where the symptoms will reflect the regions affected. Neurodegenerative disorders including Alzheimer’s disease (AD), Parkinson’s disease (PD) and frontotemporal ... -
Early detection of ESSENCE in Japanese 0-4-year-olds. Studies of neurodevelopmental problems in the community and in clinics
(2018-02-14)BACKGROUND: Early identification of children with neurodevelopmental problems/ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations) is a critical issue both in the community and in clinical ... -
Traffic Light System-BasicADL (TLS-BasicADL) Development, reliability, validity, clinical utility and patient perspective
(2018-01-23)Aim: To describe the development of Traffic Light System-BasicADL (TLS-BasicADL), and procedures to establish properties of reliability, validity, clinical utility and patient perspective. TLS-BasicADL measures the patient’s ... -
Polycystic Ovary Syndrome. Androgen excess and insulin resistance in women: Identification of molecular targets to improve glucose homeostasis
(2018-01-08)Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in women. Women with PCOS demonstrate metabolic morbidities such as obesity, insulin resistance with compensatory hyperinsulinemia and ... -
Language ability in patients with low-grade glioma - detecting signs of subtle dysfunction
(2017-11-17)Background: Low-grade glioma (LGG) is a slow-growing brain tumour often situated in or near areas involved in language and/or cognitive functions. Consequently, there is a risk that patients develop language impairments ... -
Offenders of intimate partner violence: Aggressive antisocial behavior and mental health
(2017-10-05)Background: Studies on the impact of mental disorders on aggressive antisocial behaviors constitutes an extensive body of literature. What patterns of mental disorders that contribute the most to the development of such ... -
Piperaquine and Metabolites - Bioanalysis and Pharmacokinetics
(2017-09-28)Antimalarial piperaquine (PQ) is currently used as a partner drug with dihydroartemisinin (DHA), exhibiting high cure rates (>95%) for P. falciparum. Despite its raising usage worldwide with DHA, PQ is synthetically developed ... -
Acute and chronic effects by stimulants on behavior and striatal neurotransmission in the rat
(2017-08-18)Nicotine and amphetamines are the most widely abused stimulants. The main aim of the studies in this thesis was to investigate how these two drugs of abuse affect distinct regions of the rat brain involved in development ... -
Developing brain and systemic inflammation: a "Toll-like" link with consequences
(2017-05-24)The developing brain is vulnerable to external insults, and perinatal brain injury (PBI) is a major cause of life-long neurological syndromes such as cerebral palsy. Currently, no pharmaceutical intervention is available. ... -
Physiological role of amyloid precursor protein during neural development
(2017-05-22)Amyloid precursor protein (APP) is a type-one membrane-spanning protein with a large extracellular N-terminal domain and a small intracellular C-terminal domain. APP first gained interest due to its involvement in the ... -
Aural rehabilitation programs for hearing aid users: Evaluating and clinically applying educational programs, supported via telephone and/or the internet and professionally guided by an audiologist
(2017-05-18)Many hearing aid users experience substantial communication difficulties that may affect their participation in daily life situations negatively. This experience can be addressed using follow-up rehabilitation programs, ... -
Subjective cognitive decline in memory clinic patients - characteristics and clinical relevance
(2017-05-12)Subjective cognitive decline (SCD) refers to concerns – symptoms - regarding one’s cognitive functioning, in the absence of objective evidence of impairment. SCD has been described as a possible stage preceding mild ... -
Affective touch throughout life: from cortical processing in infancy to touch perception in adulthood
(2017-05-09)Affective, interpersonal touch is important for forming and maintaining social bonds. In the hairy skin of humans there is a specific type of nerve fibers called C-tactile (CT) afferents which are optimally activated by a ...