Institute of Medicine / Institutionen för medicin: Recent submissions
Visas titlar 161-180 av 1073
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Epidemiological studies in de novo and secondary acute leukemia
(2018-11-23)Abstract Background Acute leukemia (AL) is a rare blood cancer with poor prognosis in adult patients. Socioeconomic factors are known to impact cancer outcomes, but have not been adequately examined among adult AL patients. ... -
Systematiska kunskapsöversikter; 13. Suicide in the employed population: A review of epidemiology, risk factors and prevention activities
(Arbets- och miljömedicin, Göteborgs universitet, 2018-11-21)This review described current evidence about the relationship between workplace exposures and suicidal outcomes, including thoughts about suicide, suicide attempts, and death due to suicide. First, an overview of suicide ... -
Platelet activation and aggregation: Clinical and experimental studies
(2018-11-21)Background: Dual antiplatelet therapy with acetylsalicylic acid (ASA) and the adenosine diphosphate (ADP)-receptor antagonist ticagrelor increases the risk of bleeding complications during cardiac surgery. The overall aim ... -
Health hazards and cancer in relation to occupational exposures among Swedish seafarers
(2018-11-19)This thesis explores health hazards for seafarers in the Swedish merchant fleet, and occupational risks for lung cancer, mesothelioma and hematologic malignancy (HM). A special focus has been exposure to benzene and biomarker ... -
Defining the importance of protein geranylgeranylation in innate immunity
(2018-11-19)RHO family proteins and other intracellular proteins are prenylated with a 20-carbon lipid—a product of the cholesterol synthesis pathway—by protein geranylgeranyltransferase type I (GGTase-I). Prenylation is widely believed ... -
Abdominal Aortic Aneurysm, aspects on diagnosis and treatment
(2018-11-16)Background An abdominal aortic aneurysm (AAA) is an abnormal widening of the aorta with a risk of rupture if it grows to a large diameter. Rupture ... -
Adherence to lipid-lowering medications and cardiovascular disease prevention in type 2 diabetes mellitus
(2018-11-07)Background and aims: Globally, cardiovascular disease (CVD) is the major cause of death among patients with type 2 diabetes mellitus (T2DM). Improved control of LDL cholesterol with lipid-lowering medications and patients’ ... -
Diffuse large B-cell lymphoma - proteomic and metabolomic studies on prognosis and treatment failure
(2018-11-05)Abstract Background and aim: Every year almost 600 patients in Sweden are diagnosed with diffuse large B-cell lymphoma (DLBCL), the most common lymphoma, and with immunochemotherapy, approximately 60 % are cured. Yet, for ... -
Host-Virus Interactions in Asthma and COPD
(2018-10-26)Asthma and chronic obstructive pulmonary disease (COPD) are associated with periods of worsened symptoms, known as exacerbations. Severe exac-erbations can result in hospitalisation, irreversible decline of the disease and ... -
Women's and Men's Health care utilisation from a cost perspective
(2018-10-23)The aim of this thesis was to explore sex differences in health care utilisation and costs (i) in a region in Sweden, (ii) in treatment of dialysis patients across the region, and (iii) in the treatment of specified ... -
Nutritional metabolomics: The search for dietary exposure variables
(2018-10-19)To establish associations and causation between diet and health, objective and reliable methods are needed to measure dietary exposure. Metabolomics provide an unbiased tool for exploring the modulation of the human ... -
Vitamin D in Somali women living in Sweden
(2018-10-02)Introduction: Sunlight is the major source of Vitamin D synthesis. Information regarding vitamin D, bone status and general health in Somali women living in Sweden is limited. Vitamin D binding protein (DBP) is the major ... -
Epidemiological aspects of cardiovascular morbidity and mortality among individuals with diabetes: the relative importance of cardiovascular risk factors
(2018-09-21)Background: Long-term trends of cardiovascular complications and death among patients with diabetes have not been studied extensively. In addition, we aimed to examine the effect of multifactorial risk factor control, as ... -
Microbial modulation of metabolic diseases
(2018-09-13)The gut microbiota, the ensemble of microorganisms living in the gastrointestinal tract, and the host have a mutualist relationship. Alterations of this delicate equilibrium can lead to changes in microbiota composition ... -
Critical conditions for co-workership in healthcare organizations: A workplace health promotion perspective
(2018)The workplace is well-established as one of the priority settings for promoting health in a large population. To achieve a good work environment, cooperation between managers and employees is essential. However, there is ... -
Systematiska kunskapsöversikter; 12. Arbejdsrelaterede risikofaktorer for slidgigt i tommelens rodled
(Arbets- och miljömedicin, Göteborgs universitet, 2018-09-11)Denna utgåva (Arbete och Hälsa 2018;52(4)) ingår i den serie av systematiska kunskapssammanställningar som ges ut av Göteborgs Universitet med finansiellt stöd av AFA Försäkring. Dessa kunskapssammanställningar hade sin ... -
Chemokine responses and T cell recruitment in central nervous system alphaherpesvirus infections
(2018-08-29)This thesis is focused on members of the alphaherpesvirus family; the two herpes simplex viruses and varicella zoster virus. Herpes simplex virus type 1 mainly causes cold sores and type 2 gives rise to genital blisters. ... -
STK25 as a regulator of lipid accumulation
(2018-08-24)Type 2 diabetes mellitus (T2DM) and nonalcoholic steatohepatitis (NASH), a progressive form of nonalcoholic fatty liver disease (NAFLD), have become widespread metabolic disorders that have reached epidemic proportions. ... -
Priority setting in health care and public health. The role of health economics
(2018-08-23)The aim of this thesis is to analyze the role of health economics for priority setting in health care and public health. Four papers provide the basis for the analysis. Paper I contains an application of a typical ... -
Cardiovascular health promotion among Nepalese mothers with young children: Need assessment, development, implementation, and impact of the HARDIC trial
(2018-06-07)Background Nutritional transition toward a high-fat and high-energy diet, decreasing physical activity level, and poor knowledge about cardiovascular health contribute to a rising burden of cardiovascular disease in ...