Institute of Clinical Sciences / Institutionen för kliniska vetenskaper: Recent submissions
Now showing items 161-180 of 582
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Chronic limb-threatening ischaemia - Prognosis after intervention
(2019-04-26)Introduction: Lower-extremity arterial disease (LEAD) is a major health problem worldwide. Chronic limb-threatening ischaemia (CLTI) is the most severe manifestation of LEAD. Open or endovascular recanalization is recommended ... -
Nonsynostotic plagiocephaly: Prevention strategies in child health care
(2019-04-18)The aim of this project was to assess whether it is possible to prevent nonsynostotic plagiocephaly while still promoting safe infant sleeping practices. A continuing education including guidelines was developed for child ... -
Strain echocardiography in the critically ill patient
(2019-04-12)In this thesis, strain echocardiography by two-dimensional speckle tracking imaging (2D-STI), was used for the evaluation of left ventricular (LV) and right ventricular (RV) function in critically ill patients with septic ... -
Strategies for optimisation of 177Lu-octreotate therapy – exploring local administration and combination therapy regimens
(2019-04-12)Neuroendocrine tumours (NETs) are a group of heterogeneous tumour types that originate in hormone-producing organs. Patients with NETs are often diagnosed after the primary tumour has metastasised. One treatment option for ... -
Surgical Management of Rib Fractures Following Trauma
(2019-04-08)Background: Surgical management of chest wall injuries has received increasing attention in recent years. The aim of this thesis was to study the mechanism of injury (MOI) in relation to chest wall injury patterns and ... -
Anterior Cruciate Ligament Reconstruction - Early predictors of outcome
(2019-03-21)The rupture of the anterior cruciate ligament (ACL) is a serious injury, often resulting in functional instability and increased laxity of the knee joint. Patients suffering an ACL injury run the risk of further ... -
Long-term survival and prognostic factors in endometrial cancer - a populationbased cohort study
(2019-03-14)Aims: The over-all aims of this thesis were to evaluate the associations between prognostic factors and excess mortality rate, between socioeconomic and immigrant status and incidence rate, in endometrioid (EEC) and ... -
To predict results of breast cancer therapy
(2019-03-06)We have used the almost complete national Swedish Cancer register, regional quality management register and one randomized adjuvant endocrine trial to study, the effect of radiotherapy in breast cancer with 1-3 positive ... -
Prognostic factors and tumor treatments in hepatocellular cancer
(2019-03-04)Background: Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related death worldwide. Prognosis is related to tumor burden, liver function, and performance status as well as treatment factors. ... -
Barnfetma och Metabola Syndromet hos förskolebarn - tidiga faktorer och identifiering av riskindivider från ett longitudinellt perspektiv
(2019-02-15)Background: Overweight and obesity have increased worldwide and affect children at ever younger ages, resulting in cardiovascular disease and type 2 diabetes even in adolescents. This illustrates the importance of identifying ... -
Regenerative effects of mesenchymal stem cell-derived exosomes
(2019-02-06)Mesenchymal stem cells (MSCs) play pivotal roles for bone regeneration by virtue of their osteogenic differentiation ability and immunomodulatory capacity. Recently, secretion of exosomes/extracellular vesicles (EVs) has ... -
Mean systemic filling pressure - from Guyton to the ICU, and back again
(2019-02-01)Introduction: Mean systemic filling pressure (MSFP) is the equilibrated vascular pressure at zero flow. Venous return (VR) driving pressure (VRdP) is the difference between MSFP and right atrial pressure (RAP). In clinical ... -
Early closure of a temporary ileostomy after rectal resection for cancer
(2019-01-16)A temporary ileostomy may reduce symptoms of anastomotic leakage after rectal resection for cancer. However, the stoma itself is associated with morbidity and early closure may reduce these symptoms. The aim of this thesis, ... -
Outcome Measures of Functioning and Physical Activity in Patients with Low Back Pain - Exemplified in Patients Who Undergo Lumbar Fusion Surgery
(2019-01-09)INTRODUCTION: Chronic low back pain (LBP) can negatively affect health in terms of disability and decreased levels of functioning and physical activity. Chronic LBP due to degenerative disc disease (DDD) is a subgroup ... -
Mesh-Based Immediate Breast Reconstruction. Complicantions and long-term results
(2019-01-09)There are few high-quality studies evaluating use of meshes in implant-based immediate breast reconstruction (IBR). This thesis analyzed current evidence of matrices and compared outcomes from the use of biological or ... -
Tonsil Surgery, studies on surgical methods and postoperative haemorrhage
(2019-01-07)Tonsil surgery is one of the most common surgical procedures in the world, with about 13,500 operations performed annually in Sweden. Sleep-disordered breathing in children and infection-related problems are the two most ... -
Person-centred prehabilitation program to improve functioning
(2018-12-13)Introduction: Low back pain is a frequently reported symptom and has turned into a global problem. For people with severe chronic low back pain, spinal fusion surgery can be a treatment option. The outcome of fusion ... -
Prostate Cancer Screening: Outcomes and Risk Prediction
(2018-12-12)Prostate Cancer Screening: Outcomes and Risk Prediction Maria Frånlund, MD Department of Urology, Institute of Clinical Sciences Sahlgrenska Academy at University of Gothenburg, Sweden ABSTRACT The Göteborg Randomized ... -
Achilles Tendon Ruptures Predictors; functional and economic impact
(2018-11-22)Acute Achilles tendon rupture is a common injury, which leads to significant morbidity in patients. Many patients never recover their full function even after long rehabilitation, whereas others make a good recovery. The ... -
On the pathogenesis of infections associated with percutaneous osseointegrated orthopaedic implants
(2018-11-22)Orthopaedic implants enable the restitution of locomotor function and improve the quality of life of many people. However, biomaterial-associated infection may occur due to the propensity of microorganisms to adhere and ...