Institute of Clinical Sciences / Institutionen för kliniska vetenskaper: Recent submissions
Now showing items 141-160 of 582
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Early childhood caries in relation to mode of delivery, preterm birth, tooth brushing habits, and signs of the metabolic syndrome
(2019-10-29)Background: Early childhood caries (ECC) is defined as the presence of one or more decayed (non-cavitated or cavitated lesions), missing (due to caries), or filled surfaces in any primary tooth of a child under 6 years of ... -
Knee ligament injuries in male professional football players
(2019-10-25)ABSTRACT Knee ligament injuries are common in professional football and entail a significant time loss from football, but studies of knee ligament injuries other than anterior cruciate ligament (ACL) injuries are ... -
Recurrent unexplained first-trimester miscarriage. Effects of acetylcalicylic acid, platelet aggregation and thyroid disease
(2019-10-18)Recurrent unexplained first-trimester miscarriage. Effects of acetylsalicylic acid, platelet aggregation and thyroid disease. Lennart Blomqvist, Department of Obstetrics and Gynecology, Institute of Clinical Sciences, ... -
Upper and Lower Motoneuron Lesions in Tetraplegia - Diagnostic and Therapeutic Implications of Electrical Stimulation
(2019-09-25)The overall objective of this thesis was to improve outcomes and predictability of the treatment of upper extremity function in patients with cervical spinal cord injury and tetraplegia by advancing the diagnostic and ... -
The bone cement implantation syndrome - epidemiology, pathophysiology and prevention
(2019-09-18)Bone cementation implantation syndrome (BCIS) has significant morbidity and mortality for patients who are undergoing cemented hip hemiarthroplasty or arthroplasty. The aim of this thesis is to contribute with information ... -
Studies of tibial fractures using the Swedish Fracture Register
(2019-09-13)This thesis has two topics. First, the creation and application of the Swedish Fracture Register (SFR) is described. Second, a series of studies of tibial fractures based on data from the SFR follows. Until the start ... -
Methotrexate and Risk of Cutaneous Melanoma
(2019-09-06)Methotrexate (MTX) is an anti-inflammatory and immunosuppressive drug commonly used to treat psoriasis, psoriatic arthritis and rheumatoid arthritis. Cutaneous malignant melanoma (CMM) is a common and dangerous type ... -
Generalized Joint Hypermobility and Specific Knee Laxity: Aspects of influence on the Anterior Cruciate Ligament Injured Knee
(2019-08-19)Injury to the anterior cruciate ligament (ACL) is one of the most serious sports-related injuries, with significant short- and long-term morbidity. Generalized joint hypermobility (GJH) and specific knee laxity are factors ... -
Radiation-induced dysphagia in head and neck cancer - risk structures and methodological aspects
(2019-08-19)Background/Aims: Swallowing difficulties are common after radiation therapy (RT) in head and neck cancer (HNC). The overall aim of this thesis was to address radiation-induced late dysphagia with regard to investigating ... -
Chest Tomosynthesis for Detection and Surveillance of Pulmonary Pathology. Studies on Cystic Fibrosis and Solid Pulmonary Nodules
(2019-06-17)Introduction: Digital tomosynthesis (DTS) is a relatively new imaging modality in thoracic imaging. The technique is based on the equipment of conventional radiography, upgraded with a moving tube that enables separation ... -
Colorectal Cancer - Evaluation of MMP as a prognostic marker and a model for peritoneal response
(2019-05-24)Background : There are about 6600 patients diagnosed with colorectal cancer in Sweden each year. Survival rates vary with cancer stage at diagnosis. The main treatment is surgery together with, in some cases, oncological ... -
International Outcomes of Total Hip Arthroplasty: Influence of Patient, Implant, and Surgical factors on Total Hip Arthroplasty Survivorship in Sweden, the US, and Australia
(2019-05-22)Abstract Background Hip osteoarthritis (OA) is debilitating disease resulting in pain, stiffness, and reduced physical function. Although total hip arthroplasty (THA) is a successful treatment for OA, some THAs require ... -
Development of individualized surgical treatments for malignant melanoma
(2019-05-17)Background: Cutaneous melanoma is a malignancy with an increasing incidence worldwide, especially in northern Europe. The aim of this thesis is to scrutinize the results achieved by traditional surgery and the opportunities ... -
Evaluation of regulator of G-protein signaling 2 (RGS2) at different stages of prostate cancer - Significance and clinical potential
(2019-05-15)Prostate cancer (PC) is often a slow-growing and symptom-free disease with good prognosis. However, a substantial number will progress, ultimately metastasize if left untreated and finally kill the patient. The standard ... -
Immunological effects of isolated regional perfusion in malignant melanoma
(2019-05-08)Malignant melanoma patients with metastatic disease confined to the limbs or liver may be treated with hyperthermic isolated regional perfusion with a chemotherapeutic agent, most commonly melphalan. This procedure enables ... -
Ultrasound measurement of cervical length in the second trimester of pregnancy for prediction of preterm delivery
(2019-05-07)Abstract Background: Short cervical length is a risk factor for preterm delivery (PTD) and screening of cervical length using transvaginal ultrasound in the second trimester is a proposed method to find women at risk Aims: ... -
Delayed and cancelled orthopaedic surgery; Causes and consequences
(2019-05-06)Extended waiting time, over-booked waiting lists and cancelled and delayed surgical procedures are realities for some patients treated at orthopaedic clinics in Sweden. This situation affects the prioritisation procedures ... -
Aspects on colostomy construction, complications and stoma function
(2019-04-30)Aim: The aim of this thesis was to evaluate the importance of surgical technique for stoma complications as well as stoma function in patients operated with colostomy. Methods: Five papers are included: Three observational ... -
Tumour evolution and novel biomarkers in breast cancer
(2019-04-30)Several gene signatures have been proposed in the past two decades to improve outcome prediction for breast cancer patients and to guide treatment decisions. Current treatment guidelines, however, primarily focus on ... -
Chronic Rhinosinusitis with Nasal Polyps - Symptoms, Heredity and Genetics
(2019-04-26)ABSTRACT Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by long-term inflammation of the paranasal sinuses combined with bilateral glassy protuberances from the middle meatus of the nasal cavity. This ...