Institute of Clinical Sciences / Institutionen för kliniska vetenskaper: Recent submissions
Now showing items 341-360 of 582
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Children injured in traffic in a medical and psychosocial perspective : causes and consequences
(2014-04-25)Aim: To examine the causes and consequences of road traffic injuries in children from a physical and psychosocial perspective, and to identify unfavourable circumstances and children who are at risk of injury and ... -
Aspects on Minimally Invasive Surgery for Rectal Tumours
(2014-04-16)Background: Transanal endoscopic microsurgery (TEM) and laparoscopic rectal resection are minimally invasive methods of surgery for rectal tumours. One aim of this thesis was to analyse the inflammatory response after ... -
Therapy of neuroendocrine tumors with 177Lu-octreotate - Human tumor cell types and models and optimization of treatment
(2014-04-11)Neuroendocrine (NE) tumors (NET) have often metastasized at the time of diagnose, which makes it hard to cure patients with NET. Radiolabeled hormone analogues (especially somatostatin analogues, SS) can be used for ... -
Health, nutrition and growth in infancy - a child health care perspective
(2014-04-04)Abstract Early childhood is recognised as a key period for the new family in which to promote health. There is evidence that infant feeding is one of the most influential factors affecting growth, development and life-long ... -
Pharmacokinetics and dosimetry in intraperitoneal radioimmunotherapy with 211At
(2014-03-24)The prognosis for patients diagnosed with disseminated cancer is often poor. Radioimmunotherapy (RIT) is a new approach to treat disseminated disease. The aim is to target tumor cells with monoclonal antibodies (mAbs) ... -
Respiratory and esophageal morbidity in adults with repaired esophageal atresia
(2014-03-24)Background: Esophageal atresia (EA) often leads to persistent esophageal and respiratory symptoms, as well as impaired esophageal and lung function in adulthood. The reasons for this, and the connections between symptoms ... -
Ulcerative Colitis - Surgery Outcome and Pathophysiological Aspects
(2014-03-14)Background: Ulcerative Colitis (UC) is a chronic inflammatory bowel disease; the etiology is mainly unknown. Around 30% of the patients are treated by surgery. The aims of this thesis were to evaluate outcome after specific ... -
Titanium Oxide and Bone Anchorage: Role of the Complement System, and Delivery of Osteoporosis Drugs from Mesoporous TiO2
(2014-03-07)The clinical success of bone implants of titanium (Ti) is largely ascribed to the biological performance and the physicochemical properties of the outermost titanium(IV)dioxide (TiO2) layer. Several advancements have been ... -
Tumour vasculature, oxygenation and radiosensitivity - a numerical modelling study
(2014-03-07)This thesis aims to investigate theoretically how parameters such as vessel density, blood oxygenation, blood velocity, spatial oxygen variation along vessels, tissue oxygen consumption and their distributions in uence ... -
Diabetes under seven (DU7). Aspects of glycaemic control, hypoglycaemia, nutrition and physical activity in children younger than seven years with type 1 diabetes mellitus
(2014-03-06)Aim: The aim of this thesis is to elucidate the specific challenges in insulin treatment for children younger than seven years with type 1 diabetes, with a focus on glycaemic control, hypoglycaemia, nutrition and physical ... -
Psychosocial support needs after a breast cancer diagnosis
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Bone and Cartilage Regeneration: Wnt Signaling Pathway in Healing
(2014-02-10)The Wnt signaling pathway plays a central role in bone and cartilage embryonic development, processes that are recapitulated during regeneration. Imbalance in such well conserved and complex system often contributes to ... -
Microdosimetry of radiohalogens in thyroid models
(2014-02-10)The radiohalogens 123I, 124I, 125I, 131I, and 211At are routinely used or proposed for diagnostic and therapeutic purposes. The different characteristics and application areas of these radioiodine isotopes, together with ... -
Discogenic pain - A diagnostic challenge
(2014-01-31)Low back pain (LBP) is a common health complaint with a lifetime prevalence up to 80%. Patients with discogenic pain constitute a minority of all with LBP but represent an important group with substantial personal consequences ... -
Improving care of children with cancer in Egypt
(2013-12-23)Aims: More than 70 percent of the children diagnosed with cancer in Egypt die every year. In Sweden the corresponding figure is close to 20 percent. The aims of this study was to investigate psycho-oncological predictors ... -
Fetma och övervikt i barndomen - tidig identifiering av riskfaktorer
(2013-12-20)Background: The incidence of childhood obesity is increasing. Many children become obese during preschool years and stay obese, with lifelong health consequences, such as impaired insulin sensitivity. There is growing ... -
High-risk breast cancer: From biology to personalized therapeutic strategies
(2013-12-13)Adjuvant treatment regimens for breast cancer are primarily based on patient- and tumor-related factors, e.g. patient menopausal status, tumor stage and histological grade, and the status of molecular tumor markers (HER2/neu ... -
Transpulmonary pressure during mechanical ventilation
(2013-12-13)Background: Mechanical ventilation can aggravate lung injury by repetitive opening and closing of lung units, overdistention and undue pressure on pulmonary structures. Guidelines exist for lung protective ventilation, but ... -
TRISMUS Incidence, Effects on Health-Related Quality of Life and Development of the Gothenburg Trismus Questionnaire
(2013-11-18)The word trismus is modern latin, derived from the greek word ”trismos” meaning ”grinding” or ”rasping”. Trismus is defined as a limitation in the mouth/jaw-opening ability due to a reduced mandible mobility. A Maximal ... -
Early Diagnosis of Epithelial Ovarian Cancer - Analysis of Novel Biomarkers
(2013-11-04)Early Diagnosis of Epithelial Ovarian Cancer - Analysis of Novel Biomarkers Björg Kristjánsdóttir Department of Obstetrics & Gynecology, Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg, ...