Institute of Clinical Sciences / Institutionen för kliniska vetenskaper: Recent submissions
Now showing items 321-340 of 582
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Total hip replacement in immigrants and Swedish patients. Evaluation of preoperative care, socioeconomic background, patient-reported outcomes and risk of reoperation
(2014-11-28)Total Hip Arthroplasty (THA) aims to reduce pain and improve mobility, function and quality of life in patients with osteoarthritis, when non-surgical treatment has failed. Despite good or excellent results in the majority ... -
Voice Rehabilitation and Functional Outcomes Following Radiotherapy for Laryngeal Cancer
(2014-11-12)The overall aim of this thesis was to evaluate the effects of radiotherapy and voice rehabilitation on voice function and Health Related Quality of Life (HRQL) following treatment for laryngeal cancer. Patients treated ... -
Genotypic and phenotypic spectrum of mitochondrial diseases with focus on early onset mitochondrial encephalopathies
(2014-10-07)Early-onset mitochondrial encephalopathies comprise a challenging group of neurodegenerative disorders. This is due to their progressive nature, often leading to major disability and premature death, as well as their ... -
Haemostasis during pregnancy, labour and postpartum haemorrhage
(2014-10-07)Background: Haemostatic disorders are common in obstetric complications and may result in more severe complications if not detected. There is limited knowledge about viscoelastic methods, fibrinogen and Factor XIII and how ... -
Effects of antiresorptive agents on inflammation and bone regeneration in different osseous sites - experimental and clinical studies
(2014-09-29)ABSTRACT The biological mechanisms involved in bone regeneration in osteoporotic bone and the effect of antiresorptive drugs in relation to surgically inserted biomaterials are not fully understood. Improved osseointegration ... -
Non-attendees need attention - Determinants and interventions affecting participation in cervical cancer screening
(2014-09-19)Aim: Non-attendance is the foremost screening-related risk factor for cervical cancer. The overall aim of this thesis is to contribute to preventing cervical cancer by focusing attention on non-attendees, assessing ... -
Experimental and population-based studies on colorectal cancer - Thymidine phosphorylase as a potential biomarker
(2014-09-05)Background: Colorectal cancer (CRC) is one of the most common malignancies, and the only reliable treatment option for cure is surgery. Method: Quantitative real-time polymerase chain reaction was used to analyze the ... -
Neuroinflammation and pain
(2014-09-05)ABSTRACT Background: Persistent pain that remains long after the physiological trigger has been resolved is a disabling condition. A possible mechanism for the transition from acute physiological pain to persistent pain ... -
On the treatment of tibial fractures using the Ilizarov fixator
(2014-08-29)The aim of this thesis was to analyse the results of the Ilizarov method in patients with different types of tibial fracture and compare them with conventional methods, in terms of primary union, complication rates, ... -
Experimental models with specific approaches to augment human fetal liver cell engraftment
(2014-05-27)Experimental models with specific approaches to augment human fetal liver cell engraftment Pradeep Patil Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg Background: ... -
Experiences of IVF - from a patient perspective
(2014-05-23)The overall aim of this thesis was to assess the quality of life and quality of care from a patient perspective, in relation to IVF treatment. This was done by: - assessing infertile couples’ short-term emotional ... -
Testosterone, 17β-estradiol and pubertal growth
(2014-05-20)Background and aims: It is well established that the interaction of sex steroids with the growth hormone (GH)/ insulin-like growth factor 1 (IGF-1) axis is of major importance in children for normal pubertal growth. However, ... -
The osteogenic potential of human mesenchymal stem cells: Novel markers and key factors for differentiation
(2014-05-14)Mesenchymal stem cells are multipotent stem cells with ability to differentiate into cells of the connective tissue lineage, such as adipocytes, osteoblasts and chondrocytes, both in vitro and in vivo. The main objective ... -
Diagnosis and monitoring of sport-related concussion
(2014-05-13)Background: Concussions are one of the most common sport-related injuries and it is known that they cause axonal and glial damage, and that there are risks for long-term effects. The aims of this thesis were to find possible ... -
Two New Non-invasive Treatment Methods for Otitis Media with Effusion in Children and Obstructive Sleep Apnoea in Adults
(2014-05-12)Otitis media with effusion (OME) in children and obstructive sleep apnoea (OSA) in adults are common conditions in medicine. Several surgical and non-surgical methods have been suggested for treatment of these diseases. ... -
Therapy with 177Lu-octreotate - pharmacokinetics, dosimetry and kidney toxicity
(2014-05-12)177Lu-octreotate is used for treatment of patients with somatostatin receptor expressing neuroendocrine tumors in some clinics using a standard schedule. Renal and bone marrow toxicity are the main limiting factors. Results ... -
Characterizing and modulating the effects of ionizing radiation to the juvenile hippocampus
(2014-05-09)Survival rates after childhood cancer treatment have improved, leading to a growing population of survivors. Radiotherapy is an important tool for curing cancer in the brain. Unfortunately, radiotherapy is associated with ... -
Molecular and cellular interactions on noble metal nanopatterned surfaces − applications towards bone, soft tissue and infection control
(2014-05-09)Biomaterial-associated infection is recognised as one of the main risks for failure of medical devices. The presence of a foreign material in tissues has been suggested to compromise the ability of host cells to eradicate ... -
Studies on glycosphingolipids in regenerative medicine
(2014-05-09)Regenerative medicine, including stem cell based therapies and xenotransplantation, is a new and developing field that aims to restore normal function in end stage cell/organ failure. However, in therapeutic settings ... -
Detection of pulmonary nodules in chest tomosynthesis: Comparison with chest radiography, evaluation of learning effects and investigation of radiation dose level dependency
(2014-05-05)Chest tomosynthesis is a relatively recently introduced technique in healthcare, which produces section images of the chest at a lower radiation dose than computed tomography (CT) and with better depth resolution than ...