Institute of Clinical Sciences / Institutionen för kliniska vetenskaper: Recent submissions
Visas titlar 201-220 av 582
-
Adolescent and young adult cancer survivors - body image and sexual health
(2018-04-25)Background Adolescent and young adult cancer survivors constitute a group in society of which the numbers are increasing. To optimize rehabilitation efforts, we need to understand the possible physical and psychological ... -
On minimally invasive treatment of Dupuytren's contacture
(2018-04-12)Dupuytren’s disease is a common, benign disease in which myofibroblasts in the aponeurosis of the hand start to proliferate, contract and produce pathological collagen. This results in a Dupuytren cord, which eventually ... -
Renal artery stenosis. Aspects of diagnosis and endovascular treatment.
(2018-03-23)Background. Renal artery stenosis (RAS) becomes haemodynamically significant when it reduces the arterial pressure below the threshold for autoregulation of renal perfusion. Physiological responses to reduced renal perfusion ... -
Prognostic impact of coronary microvascular funtion in patients with ischemic heart disease.
(2018-03-09)Background: Ischemic heart disease is the leading cause of death globally. Despite recent advances in interventional and medical therapies, survivors of myocardial infarction are at high risk of recurrent cardiovascular ... -
Mechanisms of intestinal tumor initiation and progression in ApcMin mouse model of colorectal cancer
(2018-03-02)Colorectal cancer (CRC) is a cancer that occurs in the colon or rectum and is one of the most common cancer forms and a leading cause of cancer death in the Western world. The majority of CRCs are caused by inherited or ... -
Epidemiology, diagnostics and treatment of non-melanoma skin cancers
(2018-02-23)Skin cancer, including malignant melanoma and non-melanoma skin cancer (NMSC), is a growing problem due to the increasing incidence in Sweden and in other Caucasian populations. NMSCs are diagnosed as often as all other ... -
Longitudinal outcome following total hip replacement. Time trends, sequence of events and study of factors influencing implant survival and mortality
(2018-02-23)Osteoarthritis of the hip is a common, debilitating and symptomatic joint disease. The disabling symptoms can be successfully treated with a total hip replacement (THR). It is known that the majority of patients do well ... -
Methylome and Transcriptome Profiling of Hepatocytes Derived from Human Pluripotent Stem Cells
(2018-02-22)Six hundred million people suffering from liver diseases worldwide of which the lethality is two million. Freshly isolated hepatocytes from the liver have been used for transplantation purposes and are extensively used to ... -
The percutaneous implant. The effects of design, host site and surgery on the tissue response
(2018-02-14)This research project focuses on the multiple challenges associated with implants that breach the skin. The role of device design, host site, and surgical approach on tissue response and outcome are evaluated, experimentally ... -
Renal denervation in patients with resistant hypertension
(2018-02-05)BACKGROUND Catheter-based renal denervation (RDN) is a potential modality in the treatment of patients with resistant hypertension (RH). The biological effects of RDN are not fully comprehended and studies examining its ... -
Distal radioulnar joint: arthroplasty and strength assessments
(2018-01-30)The growing interest in distal radioulnar (DRUJ) disorders underlines the need for further improved evaluations of treatment outcome. Load-bearing and optimising torque are important features of the DRUJ, but they are ... -
Isocapnic hyperventilation in anaesthesia practice. Clinical and experimental studies
(2018-01-30)Abstract Background: Isocapnic hyperventilation (IHV) has been shown to shorten recovery time after volatile anaesthesia by accelerating elimination of inhalational agents by increasing minute ventilation while maintaining ... -
Wear and migration in total hip arthroplasty measured with Radiostereometric Analysis. Methodological aspects and clinical studies
(2018-01-19)Total hip arthroplasty (THA) aims to relieve pain, increase hip function and improve quality of life for patients with end- stage osteoarthritis of the hip who do not benefit from non-surgical treatment. Despite constant ... -
Paediatric sleep-disordered breathing - diagnostics and treatment
(2018-01-17)Sleep-disordered breathing (SDB) in children causes multiple health problems and diminished quality of life. It is usually caused by tonsil and adenoid hypertrophy and is traditionally treated with adenotonsillar surgery. ... -
Midkine in Advanced Prostate Cancer - Biological Impact and Biomarker Potential
(2017-12-15)Prostate cancer (PC) is generally an androgen-driven disease, why androgen deprivation therapy (ADT) is the cornerstone for treatment of advanced and metastatic hormone-naïve PC (HNPC). ADT generally offers a good initial ... -
Renal perfusion, function and oxygenation after major surgery and in septic shock
(2017-11-24)Acute kidney injury (AKI) is a common and dreaded complication to severe illness and major surgery, with major impact on mor- bidity and mortality. The aim of this doctoral thesis was to increase the knowledge on renal ... -
Achilles tendon rupture: the evaluation and outcome of percutaneous and minimally invasive repair
(2017-11-17)Acute Achilles tendon rupture is common and has increasing incidence. This is thought to be due to increasing activity and sports participation in middle age. Sustaining an Achilles tendon rupture means a long rehabilitation ... -
Acute Achilles tendon rupture - The impact of calf muscle performance on function and recovery
(2017-11-17)There is an ongoing debate about the optimal treatment for patients with an acute Achilles tendon rupture. The overall purpose of this thesis was to acquire a greater knowledge of the way patients recover at different time ... -
Gait and motion analysis of hip arthroplasty. Validity, reliability and longterm results
(2017-11-17)Introduction: Walking is one of the most fundamental activities of daily living in humans, when the hip joints transfer power between the lower extremities and the pelvis. Hip osteoarthritis (OA) will more or less influence ... -
Benefits and risks with digital dermoscopy and teledermoscopy
(2017-11-16)The increasing incidence of malignant melanoma and non-melanoma skin cancer (NMSC) makes it necessary to optimize the management of patients with suspicious skin lesions, from triaging, to establishing a diagnosis and ...