Institute of Clinical Sciences / Institutionen för kliniska vetenskaper: Recent submissions
Visas titlar 261-280 av 582
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Using genetics to identify epigenetic and signal transduction targets in cancer
(2016-05-12)Cancer arises mostly due to the stepwise acquisition of untamed growth capabilities by various means, ranging from genetic, epigenetic to environmental factors. With the advancement made in molecular biology and associated ... -
Anterior Cruciate Ligament Reconstruction - Graft failures, surgical techniques and patient-reported outcome measures
(2016-05-06)Injuries to the anterior cruciate ligament (ACL) can result in increased joint laxity, which often ends participation in competitive sports and may, in the medium to long term, lead to degeneration of the knee. The occurrence ... -
Urinary tract infection in small children: aspects of bacteriology, vesicoureteral reflux and renal damage
(2016-05-02)Background: Urinary tract infection (UTI) is a prevalent bacterial infection in children. The diagnosis is based on growth of bacteria in urine specimen and treatment is chosen out of knowledge of the present antimicrobial ... -
Aortic valve imaging - Towards new standards in prosthetic valve endocarditis
(2016-04-28)Background: Aortic prosthetic valve endocarditis (PVE) is a disease with high mortality, and diagnosis is difficult. Transesophageal echocardiography (TEE) has been the mainstay imaging modality in the diagnostic workup, ... -
Anatomic anterior cruciate ligament reconstruction - aspects of surgical technique
(2016-04-19)Anatomic anterior cruciate ligament (ACL) reconstruction is a concept that has gained in interest and it aims to more effectively restore native ACL anatomy and function. Despite extensive research on the topic, the optimal ... -
Clinical and arthroscopic assessment of wrist ligament injuries and instability
(2016-04-11)Wrist ligament injuries are common after trauma, especially when concomitant dislocated radius fractures are present. The diagnostics of scapholunate (SL), lunotriquetral (LT) and triangular fibrocartilage complex ... -
Imaging of hip trauma - occult, suspect and concomitant fractures
(2016-04-05)Background: Between one and nine percent of all hip fractures are occult or suspect and further examinations with computed tomography (CT) and/or magnetic resonance imaging (MRI) are vital for further handling. Statistically ... -
Outcomes of arthroscopic hip surgery in patients with Femoro-acetabular Impingement
(2016-03-29)Hip and groin problems are common, especially among athletes. The treatment of hip and groin problems has undergone rapid change during the latest 15 years, mainly due to our understanding of femoro-acetabular impingement ... -
Targeted radionuclide therapy for patients with neuroendocrine tumours with focus on normal tissue response in 177-Lu-DOTATATE treatment
(2016-03-18)Targeted radionuclide therapy with 177Lu-DOTATATE for patients with neuroendocrine tumours utilises the frequent overexpressing of somatostatin receptors on the tumour cells. This treatment modality has demonstrated valuable ... -
Targeting Myc-driven tumours - BETing on ATR
(2016-03-17)Cancer arises from loss of function of tumour suppressors and/or gain of function mutations in proto-oncogenes that disrupt the delicate balance required for homeostatic cell division, resulting in uncontrolled cell ... -
Early Physiotherapy in the Neurointensive Care Unit - Passive Physiotherapy Interventions
(2016-03-17)Background: In critically ill patients, treated in the neurointensive care unit (NICU) because of severe brain injury or stroke, physical activities have been restricted to a minimum due to the potential risks of complications ... -
Development of targeted alpha therapy with Bi-213 and At-211 for the treatment of disseminated cancer
(2016-03-01)Radioimmunotherapy (RIT) is a type of targeted cancer therapy. The concept behind RIT is to deliver cytotoxic ionizing radiation to tumor cells by attaching radionuclides to tumor-specific antibodies. The radioimmunoconjugates ... -
Breast Hypertrophy and outcome of Breast Reduction Surgery
(2016-02-09)Aim: The overall aim of this thesis was to improve our knowledge of breast hypertrophy in women, its associated problems, and the outcome of breast reduction. Patients and methods: I. Five hundred and twelve woman were ... -
On loading protocols and abutment use in implant dentistry. Clinical studies.
(2016-02-09)ABSTRACT Research questions: The influence of immediate or delayed loading and the use of abutments in implant dentistry with regard to peri-implant tissues and the effect of risk parameters. Methodology: Fifty partially ... -
Antecedents of Cerebral Palsy in children born at term - according to subtype, motor severity and accompanying impairments
(2016-02-05)Aims: To explore antecedents of cerebral palsy (CP) according to subtype, severity of motor impairment and accompanying impairments (epilepsy and/or cognitive impairments) in relation to neuroimaging patterns. Material ... -
Long-term follow-up of adult women with urinary tract infection in childhood
(2016-01-27)Acute pyelonephritis is common in young children and can lead to permanent renal damage. Renal damage increases the risk of complications such as hypertension and decreased renal function later in life. For women with renal ... -
Haemodynamic management in liver surgery
(2016-01-15)Background: Liver resection surgery is a potentially curative treatment for liver tumours. The liver is a highly vascular organ, and substantial intra-operative blood loss is common. Increased blood loss negatively impacts ... -
Sudden infant death syndrome-epidemiology and environmental factors. Prevention is still a challenge
(2016-01-13)Sudden infant death syndrome (SIDS) is still an important cause of death in infancy despite its declining incidence. The overall aim of this thesis was to study environmental factors influencing the risk of SIDS with the ... -
Pulse-Synchronous Intramuscular Pressure Oscillations
(2016-01-12)Background Intramuscular pressure (IMP) is measured in studies of tissue nutrition and in the diagnosis of compartment syndromes. Patients with compartment syndromes have an elevated IMP due to increased volume in a ... -
Central and Peripheral Neuroendocrine Factors in Cancer-Associated Anorexia and Cachexia
(2015-11-26)Cancer anorexia-cachexia syndrome (CACS) develops in response to tumor-host biochemical interactions. A loss of appetite (anorexia) and increased metabolism results in a progressive wasting of adipose and skeletal muscle ...