Institute of Clinical Sciences / Institutionen för kliniska vetenskaper: Recent submissions
Visas titlar 421-440 av 582
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Maintaining quality of life after prostate cancer diagnosis
(2011-09-30)Knowledge of real-life factors that are associated with men’s self-assessed quality of life after prostate-cancer diagnosis could improve the support from health-care professionals in maintaining the men’s quality of life. ... -
On the Bone Tissue Response to Surface Chemistry Modifications of Titanium Implants
(2011-09-12)Background: Surface properties of titanium implants play an important role in osseointegration. From 1990, a lot of engineering techniques have been applied to dental implant productions for improving their clinical ... -
Energy-metabolic aspects of ischemia and pre-treatment: studies in porcine myocardium
(2011-08-23)The focus of this thesis is to clarify mechanisms involved in protective pre-treatment of ischemia by carbon monoxide (CO) and ischemic preconditioning (IP), so that new pro-tective therapies can be designed. This is studied ... -
Impact of the upper gut on body fluid regulation and blood pressure in man - potential involvement of a locally expressed renin-angiotensin system
(2011-05-26)This thesis explores the role of the upper gut in the regulation of diuresis and blood pressure control in relation to the novel finding of a mucosa-located renin-angiotensin system (RAS). RAS is a regulatory super-system ... -
Aspects on Long-term Outcome After Restorative Proctoclectomy
(2011-05-26)Aspects on Long-term Outcome After Restorative Proctocolectomy Abstract Background Restorative proctocolectomy is the preferred surgical alternative for reconstruction after proctocolectomy for ulcerative colitis. ... -
Bio-psychosocial analyses of acute and chronic pain, especially in the spine - the effect of distress on pain intensity and disability.
(2011-05-26)The overall purpose was to assess factors that influence the experience of pain and disability due to acute low back pain (LBP) and chronic musculoskeletal pain (CMP). A further purpose was to outline the conceptual framework ... -
Human embryonic stem cells for bone engineering applications
(2011-05-26)The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and ... -
Radiobiological effects of alpha-particles from Astatine-211: From DNA damage to cell death
(2011-05-26)ABSTRACT In recent years, the use of high linear energy transfer (LET) radiation for radiotherapeutic applications has gained increased interest. Astatine-211 (211At) is an -particle emitting radionuclide, promising ... -
Factors influencing women´s choice of contraception
(2011-05-26)Abstract Factors influencing women’s choice of contraception Ingela Lindh, Department of Obstetrics and Gynecology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg Sweden Aims: To describe contraceptive ... -
In vitro wound healing characteristics of amelogenins
(2011-05-09)Wound healing involves the co-ordinated actions of several cell types, soluble cell mediators and extracellular matrix (ECM). This research project intended to investigate the role of certain ECM proteins in different ... -
Perinatal essential fatty acid deficiency in mice: effects on metabolism and behaviour
(2011-05-09)Maternal nutritional status during pregnancy and lactation influences the health of the adult offspring and an adequate supply of essential fatty acids is important for foetal and postnatal growth and development. The ... -
Drug research and development - case scenarios, development process, risks and benefits
(2011-05-09)BACKGROUND AND AIMS. Drug development has been classically associated with large pharmaceutical companies developing ‘blockbuster’ drugs aimed at large patient populations through high market penetration and multiple ... -
Experimental studies on ovarian cryopreservation and transplantation
(2011-05-09)Around 8% of all cancer victims are below 40 years of age and the survival after cancer treatment during childhood and reproductive years has increased considerably to be around 80% today. The clinical field of fertility ... -
On healing after periapical surgery and different retrograde root-filling materials. A clinical and histological study.
(2011-05-09)Aims: The outcome from conventional endodontic therapy does not always result in a healing of the periapical area, thus leaving a remaining lesion with or without symptoms. The primary treatment alternative is a revision ... -
Alpha-radioimmunotherapy with At-211: Evaluations and imaging on normal tissues and tumors
(2011-04-21)Alpha-radioimmunotherapy (alpha-RIT) is an internal conformal radiotherapy at the cellular level using alpha-particle emitting radionuclides. Alpha-particles have a very short range in tissues (<100 micrometer) and high ... -
Incidentally discovered adrenal tumours, adrenal metastases and pheochromocytomas - Clinical and epidemiological aspects.
(2011-04-15)With increasing use of high resolution radiological imaging incidentally discovered adrenal tumours (adrenal incidentalomas, AI) have become a common clinical problem. The aim of work-up and follow-up of patients with AI ... -
Obesity and Common Surgical Disorders, Effects on Incidence and Complications
(2011-04-14)Background: Overweight and obesity are becoming increasingly common, not only in the developed countries but also in developing countries. It is well documented that obesity increases the risk of several medical disorders; ... -
Quality of life and psychological reactions in women on first line chemotherapy for metastatic breast cancer - Correlations to tumour response and predictive factors.
(2011-03-25)Background: Health-related quality of life (HRQoL) is an important endpoint in clinical trials and as an aspect that must be considered in the treatment of patients with metastatic breast cancer. Treatment efficacy and ... -
Sexually transmitted infections: serological, microbiological and microscopical aspects
(2011-03-17)The prevalence of sexually transmitted infections (STI) is high in the adult populations world-wide but varies between populations and time periods. Since a high proportion of infected individuals are asymptomatic, diagnostic ... -
Optimization of paediatric CT examinations - An approach to minimize absorbed dose to patients with regard to image quality and observer variability
(2011-02-25)The absorbed dose to paediatric patients is important bearing in mind the increased risk of radiation-induced cancer due to exposure to X-rays at young ages. Questions have also been raised of whether a CT examination of ...