Institute of Clinical Sciences / Institutionen för kliniska vetenskaper: Recent submissions
Now showing items 101-120 of 582
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New perspectives on imaging of urinary tract infections in infants
(2020-10-20)Background: Urinary tract infection (UTI) is a common disease in infants that may lead to renal damage with an increased risk of long term complications. The diagnostic imaging aims to identify risk factors as underlying ... -
The epidemiology of cardiac arrest - In-hospital risk assessment, treatment and outcome
(2020-10-12)AIM: To describe and analyse sudden cardiac arrest, both in hospital and out of hospital, from an epidemiological perspective, by early prediction, by comparing changes over time in relation to aetiology, characteristics, ... -
Dynamic ultrasound investigation of clubfeet, 0 - 4 years of age, with normal controls
(2020-10-07)Clubfoot is one of the most common congenital deformities, 1-6/1,000 births in Europe and up to 5-6/1,000 in Polynesia. The Ponseti method is now widely regarded as the method of choice for treatment. The treatment starts ... -
Neurochemical and cognitive aftermaths of surgery - studies on short- and long-term effects of surgery and anesthesia
(2020-10-01)Background: Each year, around the world, more than 230 million patients have surgery. Improvements in healthcare have resulted in older and sicker patients undergoing surgical interventions. As a result, surgical safety ... -
Diagnosis and management of periprosthetic joint infections
(2020-09-18)Periprosthetic joint infection (PJI) is a severe complication to hip and knee arthroplasty surgery. In the light of its devastating implications for the affected patient, its great economic impact on the health care system ... -
Aspects of teamwork and intraoperative factors in the operating room
(2020-09-07)The work in high-risk environments like an operating room is complex. The operating team consist of many professions with different tasks cooperating towards a common goal, the performance of safe surgery. The operating ... -
Diagnostic aspects of skin cancer and lichen sclerosus studied with laser scanning microscopy
(2020-08-20)Histopathologic examination of tissue biopsies is the current gold standard for the diagnosis of dermatological problems. Similarly, in oncology, sentinel lymph node (SLN) biopsy is the state-of-the-art diagnostic method ... -
Predicting mortality by comorbidity for patients with hip arthroplasty: Prospective observational register studies of a nationwide Swedish cohort
(2020-08-19)INTRODUCTION: Patients with total hip arthroplasty (THA) due to osteoarthritis (OA) are usually healthy, some with a remaining lifetime of several decades after surgery. Patients with hip arthroplasty due to a femoral ... -
Optimizing postoperative radiation therapy in prostate cancer: focus on side-effects, practical implementation and dose distribution
(2020-08-18)Optimizing postoperative radiotherapy in prostate cancer: focus on side effects, practical implementation and dose distribution Karin Braide, MD Department of Urology, Institute of Clincal Sciences Sahlgrenska Academy, ... -
Time-lapse technology in the IVF laboratory. Assessing safety and human embryo development
(2020)Background: Time-lapse monitoring of human embryos is becoming increasingly utilized in clinical IVF laboratories. This technology allows for uninterrupted, continuous observation of embryo development without having to ... -
Aspects on the use of slowly degradable mesh in inguinal hernia surgery
(2020-06-04)Background: Synthetic non-degradable mesh used in inguinal hernia surgery can cause chronic inflammation, which in turn can lead to chronic post-operative pain (CPP). Theoretically, a degradable mesh could reduce the risk ... -
The impact of signaling factors on intervertebral disc degeneration and regeneration - studies on disc and mesenchymal stem cells from chronic low back pain patients
(2020-05-19)INTRODUCTION: Chronic low back pain (LBP) is associated with degeneration of the intervertebral discs (IVDs). Increased expressions of pro-inflammatory cytokines such as interleukin-1β (IL-1β) and matrix metalloproteinases ... -
The effect of intra-abdominal local anaesthetics following major gynaecological surgery. Clinical and experimental studies
(2020-05-18)Background: Local anaesthetics (LA), in addition to inhibition of pain signalling, also have anti-inflammatory properties. In vitro studies have demonstrated anti-proliferative and cytotoxic effect of LAs on cancer cells ... -
Biomarkers in mid-trimester amniotic fluid in relation to gestational duration and spontaneous preterm delivery
(2020-05-15)Background: The biological mechanisms and physiological pathways of pregnancy maintenance and timing of delivery are complex and multifactorial. Pregnancy clocks, partly controlled by timing mechanisms linked to fetal ... -
On tissue engineering of pig, human, and non-human primate tissues
(2020-05-07)Background: Demand for donor organs for transplantation has been increasing every year more than the actual supply of suitable donor organs. One of the major problems associated with allogeneic transplantation includes ... -
Primordial radionuclides in pit lakes in Sweden
(2020-05-07)In Sweden, there are many pit lakes, originating from limestone quarries and metal mines, with unknown status in regard to the activity concentration of radionuclides. Such knowledge is generally available only for pit ... -
Safety and quality aspects of IVF - neonatal and maternal outcomes following advanced techniques
(2020-04-15)Background: Singletons born following assisted reproductive technology (ART) have adverse neonatal outcome compared to singletons born following spontaneous conception (SC). Moreover, the women undergoing ART are at an ... -
Novel biomarkers associated with histotype and clinical outcome in early-stage ovarian carcinoma
(2020-04-15)Ovarian cancer is a collective name for multiple malignancies deriving from or involving the ovary, mainly comprising five histotypes of epithelial origin (clear-cell (CCC), endometrioid (EC), high-grade serous (HGSC), ... -
Fast-track programs in total hip and knee replacement at Swedish hospitals - influences on safety, outcome and patients' experiences
(2020-04-14)ABSTRACT Background Fast-track is a care concept that aims to enhance recovery after surgery, resulting in shortened perioperative hospital stay. By using evidence-based methods in preparation and perioperative care ... -
Hyperbaric oxygen treatment for pelvic radiation-induced injuries. From a multicenter randomized controlled trial to an experimental cell model
(2020-04-03)Introduction Cancer is affecting a growing number of persons. Still, the treatment and survival of cancer is improving. Radiation therapy is used in the treatment of cancer. Late radiation-induced injuries afflict 5–15% ...