Institute of Clinical Sciences / Institutionen för kliniska vetenskaper: Recent submissions
Now showing items 301-320 of 582
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Folates in the treatment of colorectal cancer
(2015-05-11)ABSTRACT Folates in the Treatment of Colorectal Cancer Department of Surgery Institute of Clinical Sciences at Sahlgrenska Academy University of Gothenburg Helena Taflin Background: Colorectal cancer is one of the most ... -
Aspects on the management of patients with eosinophilic esophagitis
(2015-05-11)Eosinophilic esophagitis (EoE) is an inflammatory disorder of the esophagus characterized by symptoms of esophageal dysfunction and eosinophilia in the esophageal mucosa. This condition may affect approximately 1% of the ... -
Laparoscopic surgery as treatment for rectal cancer
(2015-05-11)Introduction Colorectal cancer is the third most common cancer worldwide, with nearly 1.4 million new cases annually, of which about one third suffer from rectal cancer. Laparoscopic surgery has in several surgical fields ... -
Who should have total hip replacement? Use of patient-reported outcome measures in identifying the indications for and assessment of total hip replacement
(2015-05-04)Background: Total hip replacement (THR) is a successful treatment for end-stage hip osteoarthritis (OA). Patients commonly seek this treatment to improve physical function, diminish pain, and ultimately to increase ... -
Excess skin after bariatric surgery - patients' perspective and objective measurements
(2015-05-04)Most of the world's population lives in countries where overweight and obesity kills more people than underweight. The only effective treatment is found to be bariatric surgery. Excess skin is an undervalued, negative ... -
Small-Scale Absorbed Dose Modelling in Selective Internal Radiation Therapy
(2015-04-30)Radioembolisation (RE), with yttrium-90 (90Y) labelled microspheres, is an increasingly common treatment method for unresectable liver tumours. The tolerable mean absorbed dose for normal liver (NL) tissue is higher in RE ... -
Methods in Diagnosing Chronic Anterior Compartment Syndrome. A clinical study in patients with exercise induced leg pain
(2015-04-27)Chronic anterior compartment syndrome (CACS) is a painful condition within one or more muscle compartment(s) in the lower leg. It impedes blood flow and muscular function due to elevated intramuscular pressure. The ... -
Prostate Diseases and the Metabolic Syndrome
(2015-04-23)ABSTRACT The overall aim of this thesis was to explore the association between the components of the metabolic syndrome (MetS), including vitamin D, and lower urinary tract symptoms (LUTS). The focus was on the relationship ... -
Predictors of Complications after Anterior Cruciate Ligament Injury
(2015-04-10)BACKGROUND: An anterior cruciate ligament (ACL) tear is a serious knee injury that frequently affects young individuals active in soccer, alpine skiing, handball and basketball. Regardless of treatment, an ACL injury is ... -
Radiobiological effects of the thyroid gland - transcriptomic and proteomic responses to 131l and 211At exposure
(2015-04-08)Radionuclides are widely used in medicine. 131I is one of the most employed radionuclides and is administered to patients either bound to tumor targeting molecules or as halide to target the thyroid or thyroid cancer. 211At ... -
Characteristics of screen-failures in prostate cancer screening
(2015-03-30)ABSTRACT Although prostate-specific antigen (PSA)-based screening has been shown to reduce prostate cancer (PC)-specific mortality with large variations in mortality reduction with different screening algorithms, the ... -
Prediction value of genetic and neuromarkers in blood and liquor in patients with severe traumatic brain injury
(2015-03-30)Background: Severe traumatic brain injury (sTBI) is the most common cause of mortality in young adults. sTBI induces variable brain damage, invisible in Computer Tomographic scans early post-trauma. Further, neurology ... -
Radiotherapy and voice rehabilitation in laryngeal cancer: Effects on quality of life and voice function
(2015-02-27)The overall aim of the thesis was to describe the effects of radiotherapy following laryngeal cancer on health-related quality of life (HRQL) and voice function as well as to assess the efficiency of voice rehabilitation. ... -
The influence of match events on injury incidence during male World Cup football - Epidemiological studies and video analysis of injuries
(2015-01-09)The aim of this thesis was to assess the effect of game-related match events on the variation in injury incidence in top-level male football. Specifically, the primary aims were to investigate: (1) a possible relationship ... -
Treating radiation-induced trismus in head and neck cancer;Exercise intervention and risk structures
(2015-01-07)Abstract The overall aim of this thesis was to investigate the incidence of trismus in head and neck cancer (HNC) and to assess the treatment of radiation-induced trismus with a structured jaw exercise program using jaw ... -
Long-gap esophageal atresia - The development of an experimental model of esophageal regeneration in vivo as an attempt to improve clinical outcome
(2015-01-07)Background: A subset (~8-15%) of the patients born with esophageal atresia (EA) suffer from a lack of esophageal tissue, which makes a primary anastomosis difficult to achieve. This is most common in patients born without ... -
Assessment of excess skin and outcome of body contouring surgery in post bariatric patients
(2014-12-08)Aim: A negative effect of massive weight loss is the development of excess skin. Excess skin causes both physical and psychological problems for those affected and their families. The overall aim of this thesis was to ... -
Prostate Cancer Screening - Aspects of Overdiagnosis
(2014-11-28)The overall aim of this thesis is to explore aspects of overdiagnosis, i.e. the diagnosis of a tumor that in the absence of screening would never have been diagnosed, in prostate cancer (PC) screening. The four papers in ... -
Biomarker discovery and assessment for prediction of kidney response after 177Lu-octreotate therapy
(2014-11-28)Patients suffering from neuroendocrine tumors are oftentimes presented with spread disease at the time of diagnosis. Therapy using somatostatin analogs is today the only potentially curative treatment option for these ...