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Decision Policies for Early Stage Clinical Trials with Multiple Endpoints
(2022-11-11)Before a drug can be prescribed to patients, it must be shown to be safe and effective for a certain indication in a controlled clinical trial (known as Phase III). Such studies are costly to run and expose patients to ... -
Modelling the effect of multimodal pain rehabilitation
(2022-09-21)Chronic pain is a cause of suffering in a large share of the population and a leading public health problem. Multimodal pain rehabilitation (MMR) is a multidisciplinary rehabilitation method commonly used to treat chronic ... -
Investigation of portfolio strategies by means of simulation
(2022-07-01)Portfolio insurance strategies are constructed to limit an investors loss but still reward them when the market goes up. In this thesis we compare two portfolio insurance strategies, Constant proportion portfolio insurance ... -
Cluster KL-UCB: Optimism for the Best, Pessimism for the Rest
(2022-06-28)The project presents an allocation strategy for the stochastic multi armed bandit when considering instances with a clustered structure. Using the architecture of the KL-UCB policy as a source of inspiration, an algorithm ... -
Artificial Intelligence for Option Pricing
(2022-06-19)This thesis addresses the issue of vulnerable underlying assumptions used in option pricing methodology. More precisely; underlying assumptions made on the financial assets and markets make option pricing theory vulnerable ... -
Machine Learning for NCC's Concrete Pile Production
(2021-09-17)In this thesis, the usefulness of machine learning (ML) is evaluated for the processes of NCC's subsidiary company Hercules. It is evaluated with regard to ML's ability to assist reduction of CO2 footprint and costs. The ... -
Knowing a Thousand Formulas Is Not The Same as Knowing Mathematics
(2021-09-07)This research is about how students at different levels of mathematical studies view, understand and study mathematics. The research is based on two theories on mathematical understanding, James Hiebert and Patricia ... -
An argument principle for generalised point residues
(2021-08-24)We define a point residue for any Artinian O-modules via Hermitian free resolutions, generalising the one dimensional residue and the classical multivariate Grothendieck point residue. We consider various definitions of ... -
FEASIBILITY ANALYSIS AND EFFICIENT ROUTING FOR A PARTIALLY AUTOMATED DELIVERY SYSTEM WITHIN CHALMERS CAMPUS
(2021-06-21)Abstract The use of autonomous driving robot transportation technology to solve the last mile delivery problem is a research hot spot in today’s logistics industry. This thesis aims to analyze the feasibility of applying ... -
Numerical Analysis of Yield Curves Implied by Two-Factor Interest Rate Models
(2021-06-15)Abstract We investigate the yield curves implied by coupon bonds in models where the market short rate is given by a two-factor stochastic model. Specifically, we investigate generalisations of the two-factor Vasicek, ... -
RISK ESTIMATION FOR PERCEPTION FAILURES IN AUTOMATED DRIVING
(2021-06-15)The failure of sensors to perceive the environment correctly is one of the primary sources of risk that needs to be quantified in the development of active safety features for autonomous vehicles. By extracting training ... -
Sequential Anomaly Detection for Log Data Using Deep Learning
(2021-06-14)Abstract Software development with continuous integration changes needs frequent testing for assessment. Analyzing the test output manually is time-consuming and automating this process could be beneficial to an ... -
Effective quasiparallelogram laws on elliptic curves over number fields
(2021-05-21)We introduce the classical theory of heights on projective space and prove explicit quasiparallelogram laws for the ordinary height and the naive height on elliptic curves over number fields with shortWeierstrass equations. ... -
Design and analysis of pre-clinical experiments using a method combining multiple comparisons and modeling techniques for dose-response studies
(2021-04-20)Abstract. Identifying and estimating the dose-response relationship between a compound and a pharmacological endpoint of interest is one of the most important and difficult goals in the preclinical stage of pharmaceutical ... -
Group Invariant Convolutional Boltzmann Machines
(2020-12-04)We investigate group invariance in unsupervised learning in the context of certain generative networks based on Boltzmann machines. Specifically, we introduce a generalization of restricted Boltzmann machines which is ... -
Convolutional neural networks for semantic segmentation of FIB-SEM volumetric image data
(2020-11-26)Focused ion beam scanning electron microscopy (FIB-SEM) is a well-established microscopy technique for 3D imaging of porous materials. We investigate three porous samples of ethyl cellulose microporous films made from ... -
Always Look on the Positive-Definite Side of Life
(2020-11-24)This thesis concerns distributions on Rn with the property of being positive-definite relative to a finite subgroup of the orthogonal group O(n). We construct examples of such distributions as the inverse Abel transform ... -
An exploratory machine learning workflow for the analysis of adverse events from clinical trials
(2020-06-26)A new pharmaceutical drug needs to be shown to be safe and effective before it can be used to treat patients. Adverse events (AEs) are potential side-effects that are recorded during clinical trials, in which a new drug ... -
Three Perspectives of Schiemann’s Theorem
(2020-06-23)Interest in the field of spectral geometry, the study of how analytic and geometric properties of manifolds are related, was sparked when Marc Kac in 1966 asked the question “can one hear the shape of a drum?”. One of ...
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