Doctoral Theses from Sahlgrenska Academy: Recent submissions
Now showing items 241-260 of 2013
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Patient safety during intrahospital transports in intensive care. Hazards, experiences and future measurements
(2020-04-16)Patient safety is an attribute of the healthcare system that minimizes the incidence of adverse events (AEs), and that entails identifying the causes of harm and preventive strategies. Intrahospital transport (IHT) of ... -
Safety and quality aspects of IVF - neonatal and maternal outcomes following advanced techniques
(2020-04-15)Background: Singletons born following assisted reproductive technology (ART) have adverse neonatal outcome compared to singletons born following spontaneous conception (SC). Moreover, the women undergoing ART are at an ... -
Novel biomarkers associated with histotype and clinical outcome in early-stage ovarian carcinoma
(2020-04-15)Ovarian cancer is a collective name for multiple malignancies deriving from or involving the ovary, mainly comprising five histotypes of epithelial origin (clear-cell (CCC), endometrioid (EC), high-grade serous (HGSC), ... -
Aspects of heart failure development and prevention in women
(2020-04-15)Heart failure (HF) is a severe progressive condition. Women more often are older and suffer from heart failure with preserved ejection fraction (HFpEF), contrasting to men who more often are younger and suffer from heart ... -
Physical fitness and exercise in adults with congenital heart disease
(2020-04-14)Background: The population of patients with adult congenital heart disease (ACHD) is growing, and the estimated life expectancy has increased. Therefore, factors related to lifestyle, such as physical activity (PA), exercise, ... -
Fast-track programs in total hip and knee replacement at Swedish hospitals - influences on safety, outcome and patients' experiences
(2020-04-14)ABSTRACT Background Fast-track is a care concept that aims to enhance recovery after surgery, resulting in shortened perioperative hospital stay. By using evidence-based methods in preparation and perioperative care ... -
Hyperbaric oxygen treatment for pelvic radiation-induced injuries. From a multicenter randomized controlled trial to an experimental cell model
(2020-04-03)Introduction Cancer is affecting a growing number of persons. Still, the treatment and survival of cancer is improving. Radiation therapy is used in the treatment of cancer. Late radiation-induced injuries afflict 5–15% ... -
Understanding normal-tissue late effects in the intestines after pelvic radiotherapy
(2020-04-02)Radiotherapy cures patients from deadly cancer, alone or in combination with other treatments. The photons must pass through normal tissue to converge on the tumor, and it is unavoidable that radiotherapy causes acute as ... -
Measurement of outcome in lumbar spine surgery
(2020-04-02)BACKGROUND. The purpose of elective lumbar spine surgery is mainly to reduce pain and to improve physical function and quality of life. The quality and results of the interventions are monitored in the Swedish spine register, ... -
Clinical implementation of novel diagnostic biomarkers for epithelial ovarian cancer - Can we improve diagnosis?
(2020-04-01)Background: Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer. The 5-year survival is about 30%, a consequence of failure to establish early diagnosis due to unspecific symptoms. The biomarker serum ... -
Invasive treatment for intermittent claudication - clinical outcomes and cost-effectiveness
(2020-04-01)Intermittent claudication (IC) is caused by obstructive arterial lesions and is characterized by effort-induced pain in the lower extremity, limiting walking distance, and reduced health-related quality of life (HRQoL). ... -
Femoroacetabular Impingement Syndrome - Outcomes of Arthroscopic Hip Surgery
(2020-03-27)Hip and groin problems are common among young, active individuals. Femoroacetabular impingement (FAI) syndrome is an important cause of hip pain and reduced hip function among these patients. Bony abnormalities at the ... -
Functional studies of purinergic and cholinergic interactions in the rat urinary bladder - Characterization of ATP-evoked urothelial release of acetylcholine
(2020-03-26)Functional interplays between different transmitter systems are known to affect the signalling of the micturition reflex arc. The functional implications of many of these interactions, such as between ATP and acetylcholine, ... -
Immunological, vascular and metabolic actions of androgens
(2020-03-10)Men have higher prevalence of cardiovascular disease (CVD) but lower risk of autoimmune disorders than women. The actions of sex steroids may be involved in the sexual dimorphism of these diseases. Although testosterone, ... -
Dizziness and Benign Paroxysmal Positional Vertigo among older adults - health-related quality of life and associated factors
(2020-03-10)Dizziness is a common complaint reported by more than 30% of persons over 70 years of age and accounts for 2% of all visits in healthcare annually. Benign paroxysmal positional vertigo (BPPV) is a common and treatable cause ... -
Transplantation of normal and decellularized syngeneic, allogeneic and xenogeneic cardiac tissue in mice and non-human primates
(2020-03-05)Introduction Because of the restricted inherent capacity of regeneration and healing, transplantation is the only treatment for end-stage heart failure but it has limitations of donor shortage and graft rejection. Cardiac ... -
On the epidemiology, clinical presentation and transmission of respiratory viral infections
(2020-03-05)Respiratory viral infections encompass a large heterogenous group of pathogens that constitute a major burden of disease globally. The various routes of transmission including airborne spread make them difficult to control. ... -
Outcomes following primary total hip arthroplasty. With focus on the surgeon & surgeons' perceptions about feedback
(2020-03-05)Den övergripande målsättningen med det här avhandlingsarbetet var att utveckla en metodologi som förser ortopedkirurgen med information om sina egna resultat efter primär höftprotesoperation samt att undersöka effekterna ... -
Prevalance and prevention of sexually transmitted viral infections in the Bolivian Amazonas
(2020-03-05)This thesis investigates the prevalence of sexually transmitted viral infections in women living in the Amazonas region of Bolivia and explores whether Bolivian medical plants can affect the immune system and prevent or ... -
Socioeconomic aspects of lifestyle and women's health: a primary care and population perspective
(2020-03-05)Aims: To estimate growth characteristics and socioeconomic factors in relation to over-weight/obesity among 4-year-old children. To explore whether a primary care lifestyle programme reached and engaged socioeconomically ...